Ruth J. Lyons

发表

Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF‐7 human breast cancer cells

E. Musgrove, R. Daly, A. Swarbrick, 2005, Journal of cellular physiology.

The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis

N. Corcoran, C. Hovens, E. Chan, 2020, Cancers.

A Cortactin-CD2-associated Protein (CD2AP) Complex Provides a Novel Link between Epidermal Growth Factor Receptor Endocytosis and the Actin Cytoskeleton*

G. Corthals, W. E. Hughes, R. Daly, 2003, Journal of Biological Chemistry.

African-specific molecular taxonomy of prostate cancer

J. Kench, D. Wedge, E. Chan, 2022, Nature.

PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation*

H. Yagi, J. Gutkind, S. Fukuhara, 2013, The Journal of Biological Chemistry.

Diagnosis of fusion genes using targeted RNA sequencing

David M. Thomas, Ira W. Deveson, S. O'toole, 2019, Nature Communications.

Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone

Linden J. Gearing, J. Mariadason, N. Corcoran, 2020, EMBO reports.

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

J. Kench, E. Chan, D. Petersen, 2016, Aging.

Human origins in a southern African palaeo-wetland and first migrations

A. Timmermann, E. Chan, D. Petersen, 2019, Nature.

Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways

Naveid A Ali, S. Clark, Jianmin Wu, 2014, Breast Cancer Research.

Mice with a Disruption of the Imprinted Grb10 Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life

Florentia M. Smith, A. Garfield, G. Cooney, 2007, Molecular and Cellular Biology.

Regulation of the Transcriptional Activity of c-Fos by ERK

J. Gutkind, M. Castellone, J. Hernández-Losa, 2005, Journal of Biological Chemistry.

African-specific prostate cancer molecular taxonomy

J. Kench, D. Wedge, E. Chan, 2021 .

Phosphorylation‐dependent binding of 14‐3‐3 terminates signalling by the Gab2 docking protein

Christoph H. Emmerich, D. James, P. Timpson, 2008, The EMBO journal.

Improved glucose homeostasis and enhanced insulin signalling in Grb14‐deficient mice

David E James, Roger J Daly, Christopher J Ormandy, 2004, The EMBO journal.

Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

A. Biankin, M. Pajic, S. Grimmond, 2021, Science advances.

TMPRSS2‐ERG fusions linked to prostate cancer racial health disparities: A focus on Africa

V. Hayes, T. Mercer, J. Blackburn, 2019, The Prostate.

Human origins in a southern African palaeo-wetland and first migrations

A. Timmermann, E. Chan, D. Petersen, 2019, Nature.

Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C

Richard J. Edwards, Erez Lieberman Aiden, Timothy P. L. Smith, 2020, GigaScience.

Identification of a Novel Human Tankyrase through Its Interaction with the Adaptor Protein Grb14*

G. Sutherland, R. Daly, R. Lyons, 2001, The Journal of Biological Chemistry.

Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers

E. Chan, V. Hayes, P. Stricker, 2022, Genome medicine.

African KhoeSan ancestry linked to high-risk prostate cancer

E. Chan, D. Petersen, P. Venter, 2019, BMC Medical Genomics.

The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer

B. Neel, R. Sutherland, S. Henshall, 2002, Oncogene.

Metagenomic analysis reveals a rich bacterial content in high‐risk prostate tumors from African men

C. Collins, V. Hayes, P. Stricker, 2019, The Prostate.

Functional characterization of cancer-associated Gab1 mutations

David R. Croucher, D. Croucher, R. Daly, 2013, Oncogene.

Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men

E. Chan, D. Petersen, V. Hayes, 2015, The Prostate.

Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer

J. Kench, E. Chan, D. Petersen, 2018, The Prostate.

Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer

David M. Thomas, Daniel L. Cameron, E. Chan, 2018, Genome research.

Whole genome optical mapping reveals multiple fusion events chained by large novel sequences in cancer

David M. Thomas, E. Chan, D. Petersen, 2017, bioRxiv.

Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.

G. Cooney, R. Daly, L. J. Holt, 2009, Molecular endocrinology.

PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation*

H. Yagi, J. Gutkind, S. Fukuhara, 2013, The Journal of Biological Chemistry.

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway.

Naveid A Ali, David R. Croucher, D. Croucher, 2013, Cancer research.

Involvement of Lyn and the Atypical Kinase in a Basal Breast Cancer Signaling Pathway

Naveid A Ali, David R. Croucher, D. Croucher, 2017 .

Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis

G. Cooney, R. Daly, L. J. Holt, 2009 .

Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response

Ira W. Deveson, David R. Croucher, P. Timpson, 2024, Science advances.