Vignir Ísberg

发表

Generic GPCR residue numbers - aligning topology maps while minding the gaps.

Chris de Graaf, Stefan Mordalski, Vignir Isberg, 2015, Trends in pharmacological sciences.

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

David E. Gloriam, Hans Bräuner-Osborne, Kasper Harpsøe, 2015, Scientific Reports.

Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

A. Hauser, D. Gloriam, P. Wellendorph, 2017, Scientific Reports.

GPCRdb: an information system for G protein-coupled receptors

David E. Gloriam, A Bairoch, F Campagne, 2015, Nucleic Acids Res..

GPCRDB: an information system for G protein-coupled receptors

David E. Gloriam, G. Vriend, D. Gloriam, 2013, Nucleic Acids Res..

The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site

David E. Gloriam, Kirsten B. Andersen, J. Åqvist, 2017, Scientific Reports.

The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW

David E. Gloriam, Kirsten B. Andersen, A. Hauser, 2017, Neurochemistry International.

Integrating structural and mutagenesis data to elucidate GPCR ligand binding.

David E. Gloriam, Kasper Harpsøe, Vignir Isberg, 2016, Current opinion in pharmacology.

GPCRdb: the G protein‐coupled receptor database – an introduction

P Kolb, G Vriend, G. Vriend, 2016, British journal of pharmacology.

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

Neil D. Rawlings, Robert D. Finn, Alex Bateman, 2015, Database J. Biol. Databases Curation.

Creating a specialist protein resource network

Neil D. Rawlings, Alex Bateman, Bernard Henrissat, 2015 .

An online resource for GPCR structure determination and analysis

Tilman Flock, Vignir Isberg, Christian Munk, 2019, Nature Methods.

Identification of the first surrogate agonists for the G protein-coupled receptor GPR132

A. Bender, D. Gloriam, H. Bräuner‐Osborne, 2015 .

Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.

D. Gloriam, P. Krogsgaard‐Larsen, A. A. Jensen, 2013, Journal of medicinal chemistry.

G Protein- and Agonist-Bound Serotonin 5-HT2A Receptor Model Activated by Steered Molecular Dynamics Simulations

David E. Gloriam, Vignir Ísberg, Flemming Steen Jørgensen, 2011, J. Chem. Inf. Model..

Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.

David E. Gloriam, D. Gloriam, P. Krogsgaard‐Larsen, 2013, Journal of medicinal chemistry.

Generic GPCR residue numbers - aligning topology maps while minding the gaps.

David E. Gloriam, G. Vriend, R. Stevens, 2015, Trends in pharmacological sciences.

A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors.

David E. Gloriam, Stefan Mordalski, Vignir Isberg, 2015, Methods.

An online resource for GPCR structure determination and analysis

David E. Gloriam, R. Stevens, M. Hanson, 2019, Nature Methods.

Computer-Aided Discovery of Aromatic l-α-Amino Acids as Agonists of the Orphan G Protein-Coupled Receptor GPR139

David E. Gloriam, Vignir Ísberg, Kirsten B. Andersen, 2014, J. Chem. Inf. Model..

Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139

David E. Gloriam, Kirsten B. Andersen, D. Gloriam, 2016, Scientific Reports.