Ivan Peng

发表

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

N. van Bruggen, M. Hedehus, J. DeVoss, 2016, Cell Death and Differentiation.

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

J. DeVoss, R. Graham, L. Diehl, 2014, Nature.

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling

M. van Lookeren Campagne, J. Hackney, E. Verschueren, 2018, Nature Immunology.

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response

J. DeVoss, A. Zarrin, Lawren C. Wu, 2015, Science Signaling.

IL-17RC Is Required for IL-17A– and IL-17F–Dependent Signaling and the Pathogenesis of Experimental Autoimmune Encephalomyelitis

D. Danilenko, W. Ouyang, P. Caplazi, 2010, The Journal of Immunology.

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

S. Rutz, P. Valdez, Z. Modrušan, 2014, Nature.

Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma

Adam R. Johnson, N. C. Ray, G. Cain, 2018, Science Translational Medicine.

Actin-Bundling Protein L-Plastin Regulates T Cell Activation

D. Danilenko, J. DeVoss, P. Allen, 2010, The Journal of Immunology.

CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis

M. Yaylaoglu, H. Collard, J. Egen, 2017, Thorax.

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

S. Gygi, J. Paulo, Z. Modrušan, 2017, eLife.

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

M. Balázs, L. Diehl, E. Chiang, 2009, Nature Medicine.

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation

Z. Modrušan, J. DeVoss, A. Zarrin, 2017, Science Signaling.

Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury

K. Stark, J. Webster, E. Verschueren, 2021, Cell Death and Disease.

Critical role of activation induced cytidine deaminase in Experimental Autoimmune Encephalomyelitis

J. DeVoss, A. Zarrin, S. Warming, 2012, Autoimmunity.

Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells

I. Mellman, Lawren C. Wu, L. Delamarre, 2015, Proceedings of the National Academy of Sciences.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes

Thijs J. Hagenbeek, Steve Lianoglou, S. Rutz, 2018, Science Immunology.

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

J. DeVoss, S. Warming, Tianbo Li, 2017, Nature Communications.

Inflammatory Arthritis Negatively Regulates Mouse a PILR

S. Kummerfeld, W. Ouyang, J. DeVoss, 2022 .

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.

Adam R. Johnson, Jun Liang, J. DeVoss, 2013, Journal of medicinal chemistry.

An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.

J. DeVoss, T. Pham, Cécile Chalouni, 2015, Molecular pharmaceutics.

Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells

I. Mellman, L. Delamarre, A. Katakam, 2015, Proceedings of the National Academy of Sciences.

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling

M. van Lookeren Campagne, J. Hackney, E. Verschueren, 2018, Nature Immunology.