Isao Kashima

发表

Dom34:hbs1 plays a general role in quality-control systems by dissociation of a stalled ribosome at the 3' end of aberrant mRNA.

T. Inada, I. Kashima, Kazuhei Kudo, 2012, Molecular cell.

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.

H. Hirano, T. Ohnishi, A. Yamashita, 2009, Genes & development.

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan.

E. Izaurralde, E. Huntzinger, I. Kashima, 2008, RNA.

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

G. Dreyfuss, S. Hoshino, N. Kataoka, 2006, Genes & development.

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

Y. Taya, T. Ohnishi, A. Yamashita, 2001, Genes & development.

The role of SMG-1 in nonsense-mediated mRNA decay.

A. Yamashita, I. Kashima, S. Ohno, 2005, Biochimica et biophysica acta.

SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.

A. Lupas, E. Conti, E. Izaurralde, 2010, Genes & development.

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

K. Anders, M. Hentze, T. Ohnishi, 2003, Molecular cell.

mRNA quality control: An ancient machinery recognizes and degrades mRNAs with nonsense codons

J. Rehwinkel, E. Izaurralde, I. Behm-Ansmant, 2007, FEBS letters.

Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich disease fibroblasts.

A. Yamashita, I. Kashima, S. Ohno, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Distant N- and C-terminal Domains Are Required for Intrinsic Kinase Activity of SMG-1, a Critical Component of Nonsense-mediated mRNA Decay*

K. Ogata, A. Yamashita, S. Ishiura, 2007, Journal of Biological Chemistry.

SMG 6 interacts with the exon junction complex via two conserved EJC-binding motifs ( EBMs ) required for nonsense-mediated mRNA decay

A. Lupas, E. Conti, E. Izaurralde, 2010 .

A functional involvement of ABCE1, eukaryotic ribosome recycling factor, in nonstop mRNA decay in Drosophila melanogaster cells.

Yoshikazu Nakamura, E. Sakota, I. Kashima, 2014, Biochimie.