Christopher W. J. Smith

发表

Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers

C. Gooding, M. Llorian, S. Sinha, 2019, eLife.

The RNA binding protein PTBP1 is necessary for B cell selection in germinal centers

Manuel D. Díaz-Muñoz, R. Coulson, C. Smith, 2018, Nature Immunology.

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

Schraga Schwartz, Tyson A. Clark, Gil Ast, 2010, Nature Structural &Molecular Biology.

The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators

J. Ule, M. Kayikci, E. Eyras, 2016, Nucleic acids research.

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3

C. Gooding, C. Smith, C. Kaminski, 2013, Nucleic acids research.

Regulated Tissue-specific Alternative Splicing of Enhanced Green Fluorescent Protein Transgenes Conferred by α-Tropomyosin Regulatory Elements in Transgenic Mice*

C. Smith, P. Kemp, P. D. Ellis, 2004, Journal of Biological Chemistry.

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing

J. Ule, N. Luscombe, C. Gooding, 2018, Cell.

Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1

C. Smith, M. Llorian, Miriam Llorian, 2007, Molecular cell.

Specific cleavage of hyper‐edited dsRNAs

C. Smith, A D Scadden, C W Smith, 2001, The EMBO journal.

Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers

C. Gooding, C. Smith, M. Llorian, 2019, bioRxiv.

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

M. Cazzola, P. Vyas, C. Smith, 2017, The Journal of clinical investigation.

Amendment history : Corrigendum ( September 2017 ) The U 2 AF 1 S 34 F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

M. Cazzola, P. Vyas, C. Smith, 2018 .

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.

A. Gavin, M. Cazzola, P. Vyas, 2018, Blood.

Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation

M. Wollerton, C. Smith, A. Furger, 2004, Molecular and Cellular Biology.

Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice

C. Smith, Elisa Monzón-Casanova, M. Turner, 2021, European journal of immunology.

Diversity of Vertebrate Splicing Factor U2AF35

V. Beneš, J. Valcárcel, W. Ansorge, 2004, Journal of Biological Chemistry.

Intron retention as a component of regulated gene expression programs

C. Smith, Aishwarya G. Jacob, Christopher W. J. Smith, 2017, Human Genetics.

Mechanism of an alternative splicing switch mediated by cell-specific and general splicing regulators

C. Gooding, C. Smith, M. Peacey, 2023, bioRxiv.

A ribonuclease specific for inosine‐containing RNA: a potential role in antiviral defence?

C. Smith, C. W. Smith, A D Scadden, 1997, The EMBO journal.

RBPMS promotes contractile smooth muscle splicing and alters phenotypic behaviour of human embryonic stem cell derived vascular smooth muscle cells

C. Smith, S. Sinha, I. Mohorianu, 2022, bioRxiv.

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation

Manuel D. Díaz-Muñoz, C. Smith, M. Llorian, 2015, Nucleic acids research.

Polypyrimidine tract-binding proteins are essential for B cell development

Louise S. Matheson, Kathi Zarnack, M. Turner, 2019, bioRxiv.

Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes

C. Smith, M. Llorian, J. Mata, 2017, Cell reports.

Dissecting domains necessary for activation and repression of splicing by muscleblind-like protein 1

C. Gooding, Christopher Edge, Christopher W. J. Smith, 2013, BMC Molecular Biology.

MBNL 1 and PTB cooperate to repress splicing of Tpm 1 exon 3

C. Gooding, C. Smith, C. Kaminski, 2013 .

A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones

C. Gooding, F. Clark, M. Wollerton, 2006, Genome Biology.

Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay

Mihaela Zavolan, Kathryn S Lilley, Nicholas J. McGlincy, 2010, BMC Genomics.

Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells

Louise S. Matheson, C. Gooding, C. Smith, 2022, bioRxiv.

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.

A. Gavin, M. Cazzola, P. Vyas, 2018, Blood.

The organization of RNA contacts by PTB for regulation of FAS splicing

C. Smith, M. Llorian, S. Curry, 2014, Nucleic acids research.

Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.

Douglas E. V. Pires, C. Gooding, C. Smith, 2016, Biochemical Society transactions.

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

J. Ule, M. Kayikci, E. Eyras, 2015, The EMBO journal.

A systems view of spliceosomal assembly and branchpoints with iCLIP

Christopher R. Sibley, J. Ule, N. Luscombe, 2018, bioRxiv.

Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

P. Simpson, S. Matthews, C. Smith, 2011, Structure.