Jachelle M. Ofrecio

发表

Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity

Jong Bae Seo, A. Birmingham, J. Olefsky, 2017, Cell.

Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling

J. Olefsky, J. Ofrecio, D. Oh, 2017, The Journal of clinical investigation.

Adipose tissue B 2 cells promote insulin resistance through leukotriene LTB 4 / LTB 4 R 1 signaling

J. Olefsky, J. Ofrecio, D. Oh, 2018 .

Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity

Dorothy D. Sears, J. Auwerx, M. Scadeng, 2011, Cell.

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization

Dorothy D. Sears, S. Subramaniam, D. Sears, 2009, Proceedings of the National Academy of Sciences.

MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice.

J. Olefsky, J. Ofrecio, G. Bandyopadhyay, 2021, Cell metabolism.

Adipocytes control food intake and weight regain via Vacuolar-type H+ ATPase

T. Ciaraldi, R. Sásik, J. Ofrecio, 2022, Nature Communications.

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

J. Olefsky, J. Ofrecio, M. Maris, 2015, Nature Medicine.

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

D. Accili, J. Olefsky, L. Qiang, 2015, Molecular metabolism.

Neutrophils mediate insulin resistance in high fat diet fed mice via secreted elastase

J. Olefsky, Dongmei Li, J. Ofrecio, 2012, Nature Medicine.

Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice

Dorothy D. Sears, D. Sears, J. Ofrecio, 2010, PloS one.

Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle.

J. Ofrecio, J. Olefsky, Joseph G. Yu, 2005, Diabetes.

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice

Dorothy D. Sears, D. Sears, J. Ofrecio, 2009, PloS one.

LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity

J. Olefsky, J. Ofrecio, M. Maris, 2015, Nature medicine.

Increased Malonyl-CoA Levels in Muscle From Obese and Type 2 Diabetic Subjects Lead to Decreased Fatty Acid Oxidation and Increased Lipogenesis; Thiazolidinedione Treatment Reverses These Defects

J. Olefsky, J. Ofrecio, Joseph G. Yu, 2006, Diabetes.

Decreased susceptibility to fatty acid-induced peripheral tissue insulin resistance in women.

J. Olefsky, Y. Kruszynska, J. Ofrecio, 2001, Diabetes.

Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.

D. S. Worrall, J. Olefsky, Y. Kruszynska, 2002, The Journal of clinical endocrinology and metabolism.

Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

Dorothy D. Sears, J. Olefsky, D. Sears, 2007, Biochemical and biophysical research communications.

Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.

Dorothy D. Sears, S. Subramaniam, D. Sears, 2011, American journal of physiology. Endocrinology and metabolism.

Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance

Mohit M. Jain, J. Olefsky, Yong-Jiang Xu, 2019, Diabetes.

G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.

Miriam Scadeng, Da Young Oh, T. Bártfai, 2012, The Journal of clinical investigation.

Adipocyte PU.1 knockout promotes insulin sensitivity in HFD-fed obese mice

J. Ofrecio, D. Oh, Y. S. Lee, 2019, Scientific Reports.

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O. Osborn, Dalila El Ouarrat, D. Lackey, 2019 .

Increased p 85 / 55 / 50 Expression and Decreased Phosphotidylinositol 3-Kinase Activity in Insulin-Resistant Human Skeletal Muscle

J. Ofrecio, J. Olefsky, Joseph G. Yu, 2005 .

LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity

J. Olefsky, M. Maris, D. Oh, 2015, Nature Medicine.