T. Konopka

发表

Genome-wide genetic screening with chemically-mutagenized haploid embryonic stem cells

Thomas M. Keane, D. Adams, T. Keane, 2016, Nature chemical biology.

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Jacob C. Ulirsch, J. Danesh, P. Deloukas, 2021, Nature Genetics.

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development

Jacqueline K. White, Denise G. Lanza, Jason D. Heaney, 2023, BMC Biology.

A pan-cancer landscape of somatic mutations in non-unique regions of the human genome

P. Van Loo, A. Flanagan, A. Verfaillie, 2021, Nature Biotechnology.

A pan-cancer landscape of somatic substitutions in non-unique regions of the human genome

P. Loo, A. Flanagan, A. Verfaillie, 2020, bioRxiv.

A pan-cancer landscape of somatic substitution mutations in non-unique regions of the human genome

P. Loo, A. Flanagan, A. Verfaillie, 2022 .

Gene expression model (in)validation by Fourier analysis

Marianne Rooman, Tomasz Konopka, M. Rooman, 2010, BMC Systems Biology.

Intratumor heterogeneity and clonal evolution in an aggressive papillary thyroid cancer and matched metastases.

D. Larsimont, V. Detours, D. Gacquer, 2015, Endocrine-related cancer.

Incremental data integration for tracking genotype-disease associations

Damian Smedley, Tomasz Konopka, D. Smedley, 2020, PLoS Comput. Biol..

Human and mouse essentiality screens as a resource for disease gene discovery

Steve D. M. Brown, Jacqueline K. White, Ghina Bou About, 2020, Nature Communications.

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line

Doris Chen, Tomasz Konopka, Tilmann Bürckstümmer, 2014, Genome research.

Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity

Markus K. Muellner, V. Theodorou, Barbara Mair, 2016, PLoS genetics.

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

David Gacquer, Peter J. Campbell, Christine Desmedt, 2015, bioRxiv.

A reversible gene trap collection empowers haploid genetics in human cells

G. Casari, G. Superti-Furga, K. Bennett, 2013, Nature Methods.

Correcting machine learning models using calibrated ensembles with ‘mlensemble’

Tomasz Konopka, T. Konopka, 2021, bioRxiv.

TriageTools: tools for partitioning and prioritizing analysis of high-throughput sequencing data

Vincent Detours, Tomasz Konopka, V. Detours, 2013, Nucleic acids research.

Parallel reverse genetic screening in mutant human cells using transcriptomics

T. Bürckstümmer, C. Bock, S. Nijman, 2016, Molecular systems biology.

Human and mouse essentiality screens as a resource for disease gene discovery

Steve D. M. Brown, Jacqueline K. White, Denise G. Lanza, 2019, bioRxiv.

Piecewise Polynomial Representations of Genomic Tracks

V. Detours, Tomasz Konopka, M. Tarabichi, 2012, PloS one.

MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated

Markus K. Muellner, Iris Z. Uras, Z. Bago-Horvath, 2016, Nature Communications.

Parallel reverse genetic screening in mutant human cells using transcriptomics

T. Bürckstümmer, C. Bock, Tomasz Konopka, 2016, Molecular systems biology.

Dimensional reduction of phenotypes from 53,000 mouse models reveals a diverse landscape of gene function

D. Smedley, Tomasz Konopka, Letizia Vestito, 2021, bioRxiv.

Proteoglycan characterization in COG 7-deficient cells

Tomasz Konopka, T. Konopka, 2014 .

New 5-Aryl-1H-imidazoles display in vitro antitumor activity against apoptosis-resistant cancer models, including melanomas, through mitochondrial targeting.

C. Pirker, W. Berger, R. Kiss, 2013, Journal of medicinal chemistry.