Lora C. Bailey-Downs

发表

Aging exacerbates obesity‐induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation

D. Sosnowska, Z. Ungvari, A. Csiszar, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents.

M. Ihnat, J. Thorpe, E. Hamel, 2014, Bioorganic & medicinal chemistry.

Adaptive induction of NF‐E2–Related Factor‐2‐driven antioxidant genes in endothelial cells in response to hyperglycemia

Kevin Pearson, R. de Cabo, F. Recchia, 2011, American journal of physiology. Heart and circulatory physiology.

Growth hormone and IGF‐1 deficiency exacerbate high fat diet‐induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging

D. Sosnowska, Z. Ungvari, A. Csiszar, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Age‐associated vascular oxidative stress, Nrf2 dysfunction and NF‐κB activation in the non‐human primate Macaca mulatta

E. Lakatta, D. Sosnowska, Mingyi Wang, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression

C. Bass, Z. Ungvari, A. Csiszar, 2011, Neuroscience.

Liver‐specific knockdown of IGF‐1 decreases vascular oxidative stress resistance by impairing the Nrf2‐dependent antioxidant response

D. Sosnowska, Z. Ungvari, A. Csiszar, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of Nrf2‐mediated antioxidant response

R. de Cabo, D. Sosnowska, Z. Ungvari, 2011, American journal of physiology. Heart and circulatory physiology.

Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging

D. Sosnowska, R. Cabo, Z. Ungvari, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Impairing the Nrf2-Dependent Antioxidant Response: A Novel Model of Vascular Aging Liver-Specific Knockdown of IGF-1 Decreases Vascular Oxidative Stress Resistance by

D. Sosnowska, F. Recchia, K. Pearson, 2011 .

17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior

M. Low, S. Brimijoin, M. Rubinstein, 2017, Aging cell.

Development and Characterization of a Preclinical Model of Breast Cancer Lung Micrometastatic to Macrometastatic Progression

P. Hauser, M. Ihnat, R. Hurst, 2014, PloS one.

Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents.

M. Ihnat, J. Thorpe, A. Gangjee, 2012, Bioorganic & medicinal chemistry.

Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression

C. Bass, Z. Ungvari, A. Csiszar, 2011, Neuroscience.

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.

R. de Cabo, D. Sosnowska, Z. Ungvari, 2011, American journal of physiology. Heart and circulatory physiology.

Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of Nrf2‐mediated antioxidant response

Z. Ungvari, A. Csiszar, Lora C. Bailey-Downs, 2011 .

Targeting dormant micrometastases: rationale, evidence to date and clinical implications

M. Ihnat, R. Hurst, L. Bailey-Downs, 2016, Therapeutic advances in medical oncology.

Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential.

M. Ihnat, J. Thorpe, E. Hamel, 2014, ACS medicinal chemistry letters.

N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastatic and antitumor agents.

M. Ihnat, J. Thorpe, A. Gangjee, 2013, Bioorganic & medicinal chemistry.

A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer

M. Ihnat, J. Thorpe, A. Gangjee, 2015, The Journal of Pharmacology and Experimental Therapeutics.

A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer

M. Ihnat, J. Thorpe, A. Gangjee, 2015 .