Tie Ke

发表

Mutation in Nuclear Pore Component NUP155 Leads to Atrial Fibrillation and Early Sudden Cardiac Death

T. Ke, Qiuyun Chen, Xianqin Zhang, 2008, Cell.

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population

Qing Yang, Mugen Liu, Fan Wang, 2011, Nature Genetics.

Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance

Xiang Ren, J. Pu, T. Ke, 2022, Circulation. Genomic and precision medicine.

Novel Roles of GATA1 in Regulation of Angiogenic Factor AGGF1 and Endothelial Cell Function*

D. Driscoll, P. He, T. Ke, 2009, The Journal of Biological Chemistry.

Candidate Pathway-Based Genome-Wide Association Studies Identify Novel Associations of Genomic Variants in the Complement System Associated With Coronary Artery Disease

Tangchun Wu, J. Chen, Y. Liu, 2014, Circulation. Cardiovascular genetics.

Novel CACNA1S mutation causes autosomal dominant hypokalemic periodic paralysis in a South American family

T. Ke, H. Mateus, Q. Wang, 2009, Journal of Human Genetics.

Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation

Xuan Luo, T. Ke, X. Tu, 2018, Human mutation.

Molecular genetics of Brugada syndrome

T. Ke, X. Tu, Q. Wang, 2010, Frontiers in Biology.

Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2.

B. Weigelt, Xiang Ren, B. Rubin, 2020, Cancer letters.

A novel de novo frame-shift mutation of the EDA gene in a Chinese Han family with hypohidrotic ectodermal dysplasia

Qinbo Yang, Changzheng Huang, Mugen Liu, 2006, Journal of Human Genetics.

A novel PAX6 mutation in a large Chinese family with aniridia and congenital cataract

T. Ke, X. Tu, Wen Chen, 2010, Molecular vision.

Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation

R. Elston, Shaoqi Rao, Chunyan Luo, 2015, PLoS genetics.

ADTRP regulates TFPI expression via transcription factor POU1F1 involved in coronary artery disease.

Qing Kenneth Wang, Xiang Ren, Chunyan Luo, 2020, Gene.

Mog1 deficiency promotes cardiac contractile dysfunction and isoproterenol-induced arrhythmias associated with cardiac fibrosis and Cx43 remodeling.

Xia Li, T. Ke, Yimei Du, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Identification of a New Co-factor, MOG1, Required for the Full Function of Cardiac Sodium Channel Nav1.5*

P. Szafranski, C. Obejero-Paz, T. Ke, 2008, Journal of Biological Chemistry.

Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer

Hui Li, T. Ke, N. Wang, 2014, British Journal of Cancer.

Regulation of CARD8 Expression by ANRIL and Association of CARD8 Single Nucleotide Polymorphism rs2043211 (p.C10X) With Ischemic Stroke

Fan Wang, T. Ke, X. Tu, 2014, Stroke.

Meta-analysis identifies robust association between SNP rs17465637 in MIA3 on chromosome 1q41 and coronary artery disease.

Y. Zhang, Fan Wang, X. Tu, 2013, Atherosclerosis.

HSF4 regulates DLAD expression and promotes lens de-nucleation.

Mugen Liu, D. W. Li, T. Ke, 2013, Biochimica et biophysica acta.

A novel de novo frameshift mutation of RPGR ORF15 is associated with X-linked retinitis pigmentosa in a Chinese family.

Mugen Liu, T. Ke, Zhao-hui Tang, 2007, Molecular vision.

BRG1 variant rs1122608 on chromosome 19p13.2 confers protection against stroke and regulates expression of pre-mRNA-splicing factor SFRS3

Y. Zhang, Tangchun Wu, Fan Wang, 2014, Human Genetics.

Significant association of rare variant p.Gly8Ser in cardiac sodium channel β4‐subunit SCN4B with atrial fibrillation

Y. Liu, T. Ke, X. Tu, 2019, Annals of human genetics.

Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation

Y. Liu, Yi Xiao, Mugen Liu, 2018, Scientific Reports.

Identification and functional analysis of two new de novo KCNMA1 variants associated with Liang–Wang syndrome

T. Ke, Chengqi Xu, D. Bartholdi, 2022, Acta physiologica.

Molecular genetic analysis of autosomal dominant late-onset cataract in a Chinese Family

Guohua Yang, T. Ke, B. Peng, 2010, Journal of Huazhong University of Science and Technology. Medical Sciences.

Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family.

Qinbo Yang, Mugen Liu, T. Ke, 2006, Investigative ophthalmology & visual science.

HSF4 is involved in DNA damage repair through regulation of Rad51.

Mugen Liu, D. W. Li, Stephen Archacki, 2012, Biochimica et biophysica acta.

[Two variants in MYOC and CYP1B1 genes in a Chinese family with primary angle-closure glaucoma].

Qing Wang, Mugen Liu, X. Dai, 2008, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

Novel CACNA1S mutation causes autosomal dominant hypokalemic periodic paralysis in a Chinese family

Ping Liu, Mugen Liu, T. Ke, 2005, Journal of Molecular Medicine.

Alpha-actin-2 mutations in Chinese patients with a non-syndromatic thoracic aortic aneurysm

T. Ke, Chengqi Xu, Q. Wang, 2016, BMC Medical Genetics.

Novel HSF4 mutation causes congenital total white cataract in a Chinese family.

Mugen Liu, T. Ke, Xu Wang, 2006, American journal of ophthalmology.

Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5‐cryab‐hspb2 signalling in zebrafish

Xuemei Bai, Fan Wang, T. Ke, 2020, Acta physiologica.

Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells.

Mugen Liu, T. Ke, Chang Li, 2008, Biochimica et biophysica acta.

Cataract mutation P20S of (cid:11) B-crystallin impairs chaperone activity of (cid:11) A-crystallin and induces apoptosis of human lens epithelial cells

Mugen Liu, T. Ke, Chang Li, 2018 .

Mechanistic insights into the interaction of cardiac sodium channel Nav1.5 with MOG1 and a new molecular mechanism for Brugada syndrome.

Xiang Ren, X. Tu, Chengqi Xu, 2021, Heart rhythm.

Molecular genetic analysis of autosomal dominant late-onset cataract in a Chinese Family

Guohua Yang, J. 俊, B. Peng, 2010, Journal of Huazhong University of Science and Technology [Medical Sciences].

Identification and characterization of a special type of subnuclear structure: AGGF1‐coated paraspeckles

T. Ke, Qiuyun Chen, Chengqi Xu, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NINJ2 deficiency inhibits preadipocyte differentiation and promotes insulin resistance through regulating insulin signaling

Mugen Liu, T. Ke, X. Tu, 2022, Obesity.

Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease.

Chunyan Luo, Fan Wang, Bo Tang, 2017, Biochimica et biophysica acta. Molecular basis of disease.