Ugo Pradère

发表

Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells

Jonathan Hall, H. Towbin, Martina Roos, 2014, Nucleic acids research.

A Small-Molecule Inhibitor of Lin28.

A. Caflisch, Jonathan Hall, H. Towbin, 2016, ACS chemical biology.

Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs

R. Schinazi, F. Amblard, S. Coats, 2014, Chemical reviews.

The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA regulation

Jonathan Hall, C. Ciaudo, F. Allain, 2019, bioRxiv.

Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC.

Jonathan Hall, J. Hall, J. Hunziker, 2016, Chemical communications.

The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation

Jonathan Hall, C. Ciaudo, F. Allain, 2022, Nature Communications.

Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition.

R. Schinazi, Vincent Roy, L. Agrofoglio, 2008, Tetrahedron.

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3′-azido-2′,3′-dideoxyguanosine-5′-triphosphates as adenosine analogs

Richard A. Stanton, J. Nettles, J. Mellors, 2011, Nucleic acids research.

A small-molecule inhibitor of Lin 28

A. Caflisch, H. Towbin, Martina Roos, 2016 .

Balancing Antiviral Potency and Host Toxicity: Identifying a Nucleotide Inhibitor with an Optimal Kinetic Phenotype for HIV-1 Reverse Transcriptase

K. Anderson, R. Schinazi, H. Mitsuya, 2012, Molecular Pharmacology.

Expeditious convergent procedure for the preparation of bis(POC) prodrugs of new (E)-4-phosphono-but-2-en-1-yl nucleosides

S. Nolan, Vincent Roy, L. Agrofoglio, 2011 .

Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain

Jonathan Hall, N. Polacek, M. Koch, 2017, Nucleic acids research.

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms.

R. Schinazi, Sijia Tao, M. Ehteshami, 2015, Journal of medicinal chemistry.

One- and Two-Dimensional High-Resolution NMR from Flat Surfaces

C. Copéret, A. Lesage, Aaron J. Rossini, 2019, ACS central science.

Site‐Specific Labeling of MicroRNA Precursors: A Structure–Activity Relationship Study

Jonathan Hall, M. Menzi, Martina Bigatti, 2016, Chembiochem : a European journal of chemical biology.

Site-Specific Difunctionalization of Structured RNAs Yields Probes for microRNA Maturation.

Jonathan Hall, U. Pradère, Ugo Pradère, 2016, Bioconjugate chemistry.

Chemical synthesis of mono- and bis-labeled pre-microRNAs.

Jonathan Hall, Martina Roos, A. Brunschweiger, 2013, Angewandte Chemie.

Towards Improved Oligonucleotide Therapeutics Through Faster Target Binding Kinetics.

Jonathan Hall, M. Menzi, H. Lightfoot, 2017, Chemistry.

Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis

S. Nolan, G. Andrei, R. Snoeck, 2008 .

Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC.

Jonathan Hall, A. Brunschweiger, M. Lucic, 2016, Chemical communications.