A. Chen

发表

Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress.

C. Yu, L. Liu, Y. Mao, 1999, Genes & development.

Mechanisms of resistance to topoisomerase inhibitors.

L. Liu, A. Y. Chen, A. Chen, 1994, Cancer treatment and research.

DNA topoisomerases: essential enzymes and lethal targets.

L. Liu, A. Y. Chen, A. Chen, 1994, Annual review of pharmacology and toxicology.

Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin.

S. Meegalla, C. Yu, L. Liu, 1994, Journal of medicinal chemistry.

Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.

T. Chou, C. Yu, L. Liu, 1993, Journal of medicinal chemistry.

DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.

B. Gatto, C. Yu, L. Liu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

A new mammalian DNA topoisomerase I poison Hoechst 33342: cytotoxicity and drug resistance in human cell cultures.

A. Bodley, C. Yu, L. Liu, 1993, Cancer research.

Studies of topoisomerase-specific antitumor drugs in human lymphocytes using rabbit antisera against recombinant human topoisomerase II polypeptide.

J. Hwang, J. Whang-peng, A. Y. Chen, 1989, Cancer research.

Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells.

C. Yu, L. Liu, M. Wani, 1991, Cancer research.

p53 selective and nonselective replication of an E1B-deleted adenovirus in hepatocellular carcinoma.

A. Ribas, L. Butterfield, W. McBride, 1999, Cancer research.

Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip

Daniel J. Barker, D. J. Barker, L. Rachdi, 2012, Diabetologia.

Human immunodeficiency virus type 1 (HIV-1) inhibition, DNA-binding, RNA-binding, and ribosome inactivation activities in the N-terminal segments of the plant anti-HIV protein GAP31.

S. Lee-Huang, H. Kung, J. Brown, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Generation of T-cell immunity to a murine melanoma using MART-1-engineered dendritic cells.

A. Ribas, L. Butterfield, W. McBride, 2000, Journal of immunotherapy.

Design of topoisomerase inhibitors to overcome MDR1-mediated drug resistance.

L. Liu, A. Y. Chen, A. Chen, 1994, Advances in pharmacology.

Sequential addition of temperature-sensitive missense mutations into the PB2 gene of influenza A transfectant viruses can effect an increase in temperature sensitivity and attenuation and permits the rational design of a genetically engineered live influenza A virus vaccine

B. Murphy, E. K. Subbarao, C. Lawson, 1995, Journal of virology.

DNA topoisomerase I-targeting drugs as radiation sensitizers.

H. Choy, M. Rothenberg, A. Y. Chen, 1999, Oncology.

Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1.

K. J. Yost, M. Kirby, N. Grazier, 2001, Journal of medicinal chemistry.

Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation.

L. Liu, E. LaVoie, N. Zhou, 2001, Biochemistry.