H. Claesson

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Leukotrienes A4 and B4 stimulate the formation of cyclic amp in human leukocytes

H. Claésson, Hans-Erik Claesson, H. Claesson, 1982, FEBS letters.

Serum-coated zymosan stimulates the synthesis of leukotriene B4 in human polymorphonuclear leukocytes. Inhibition by cyclic AMP.

C. Malmsten, H. Claésson, U. Lundberg, 1981, Biochemical and biophysical research communications.

Early growth response gene (EGR)-1 regulates leukotriene D4-induced cytokine transcription in Hodgkin lymphoma cells.

M. Björkholm, Dawei Xu, H. Claésson, 2015, Prostaglandins & other lipid mediators.

STUDIES ON THE REGULATION AND FUNCTION OF LIPOXYGENASES IN HODGKIN LYMPHOMA

T. Ekström, M. Björkholm, H. Claésson, 2014 .

Leukotriene B4 enhances activation, proliferation, and differentiation of human B lymphocytes.

H. Claésson, A. Rosén, K. Yamaoka, 1989, Journal of immunology.

Effects of leukotrienes on phenotypic properties and growth of arterial smooth muscle cells in primary culture.

J. Thyberg, L. Palmberg, H. Claésson, 1989, Journal of cell science.

Intracellular mechanisms involved in leukotriene C4-stimulated adhesion of U-937 cells.

H. Claésson, G. Skoglund, H. Claesson, 1991, Cellular signalling.

Simultaneous detection of the two main proliferation driving EBV encoded proteins, EBNA-2 and LMP-1 in single B cells.

G. Klein, N. Nagy, E. Klein, 2012, Journal of immunological methods.

Diverse expression of cytosolic phospholipase A2, 5‐lipoxygenase and prostaglandin H synthase 2 in acute pre‐B‐lymphocytic leukaemia cells

P. Jakobsson, S. Feltenmark, H. Claésson, 1995, British journal of haematology.

Effects of adenosine 3′:5′‐monophosphate and platelet aggregation on thromboxane biosynthesis in human platelets

S. Hammarström, J. Lindgren, H. Claésson, 1979, FEBS letters.

On the expression and regulation of 5-lipoxygenase in human lymphocytes.

D. Steinhilber, B. Samuelsson, O. Rådmark, 1992, Proceedings of the National Academy of Sciences of the United States of America.

On the biosynthesis of 15-HETE and eoxin C4 by human airway epithelial cells.

B. Mannervik, B. Dahlén, A. James, 2015, Prostaglandins & other lipid mediators.

Metabolism of Anandamide into Eoxamides by 15-Lipoxygenase-1 and Glutathione Transferases

H. Claésson, M. Johannesson, P. Forsell, 2012, Lipids.

Leukotriene B4 activates T cells that inhibit B-cell proliferation in EBV-infected cord blood-derived mononuclear cell cultures.

G. Klein, E. Klein, H. Claésson, 2008, Blood.

derived mononuclear cell cultures - EBV-infected cord blood Leukotriene B4 activates T cells that inhibit B-cell proliferation in

G. Klein, E. Klein, H. Claésson, 2013 .

Inhibition of platelet aggregation and elevation of cyclic-AMP levels in platelets by 13,14-dehydro PGI2 methyl ester.

C. Malmsten, H. Claésson, J. Fried, 1980, Prostaglandins and medicine.

Endogenous synthesis of prostaglandins E2 and I2 in 3T3 fibroblasts transformed by polyoma virus

J. Lindgren, H. Claésson, M. Goldyne, 1980 .

Endogenous synthesis of prostaglandins E1 and I2 in 3T3 fibroblasts transformed by polyoma virus. Effects on adenosine 3':5'-monophosphate production.

J. Lindgren, H. Claésson, M. Goldyne, 1980, Prostaglandins.

Transcriptional regulation of 15-lipoxygenase expression by promoter methylation.

C. Liu, M. Björkholm, Dawei Xu, 2004, Experimental cell research.

Biosynthesis of eoxin C4 by porcine leukocytes.

L. Backman, H. Claésson, Y. Tryselius, 2012, Prostaglandins, leukotrienes, and essential fatty acids.

On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma.

H. Claésson, H. Claesson, 2009, Prostaglandins & other lipid mediators.

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

O. Rådmark, P. Jakobsson, L. Backman, 2009, Arthritis research & therapy.

Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling.

H. Claésson, J. Erjefält, C. Andersson, 2008, American journal of respiratory cell and molecular biology.

Effects of monocyte-lymphocyte interaction on the synthesis of leukotriene B4.

P. Jakobsson, H. Claésson, B. Odlander, 1991, European journal of biochemistry.

Leukotrienes and related eicosanoids are produced by frog leukocytes.

M. Hamberg, H. Claésson, F. A. Green, 1987, Biochemical and biophysical research communications.

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase.

A. Hallberg, H. Claésson, C. Krog-Jensen, 2015, Bioorganic & medicinal chemistry letters.

The Influence of Aspirin on Release of Eoxin C4, Leukotriene C4 and 15-HETE, in Eosinophilic Granulocytes Isolated from Patients with Asthma

S. Dahlén, B. Dahlén, K. Daham, 2013, International Archives of Allergy and Immunology.

Transcriptional Regulation of 15-Lipoxygenase Expression by Histone H3 Lysine 4 Methylation/Demethylation

C. Liu, M. Björkholm, Dawei Xu, 2012, PloS one.

Epigenetic and transcriptional control of the 15-lipoxygenase-1 gene in a Hodgkin lymphoma cell line.

C. Liu, M. Björkholm, Dawei Xu, 2012, Experimental cell research.

The expression of cytosolic phospholipase A2 and biosynthesis of leukotriene B4 in acute myeloid leukemia cells

M. Björkholm, S. Feltenmark, H. Claésson, 2007, European journal of haematology.

Multiple Splice Variants of the Human Calcium-independent Phospholipase A2 and Their Effect on Enzyme Activity*

B. Kennedy, H. Claésson, P. Larsson, 1998, The Journal of Biological Chemistry.

Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet‐activating factor (PAF) receptor‐dependent mechanism

J. Frostegård, Wu, Huang, 1999, Clinical and experimental immunology.

15-Lipoxygenase-1 induces expression and release of chemokines in cultured human lung epithelial cells.

C. Liu, M. Björkholm, Dawei Xu, 2009, American journal of physiology. Lung cellular and molecular physiology.

Studies on the regulation and localization of 5-lipoxygenase in human B-lymphocytes.

P. Biberfeld, P. Jakobsson, S. Feltenmark, 1995, European journal of biochemistry.

Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells

M. Björkholm, S. Feltenmark, N. Gautam, 2008, Proceedings of the National Academy of Sciences.

Expression of 15-lipoxygenase type-1 in human mast cells.

G. Nilsson, B. Dahlén, M. Kumlin, 2007, Biochimica et biophysica acta.

Intrinsic 5-lipoxygenase activity regulates migration and adherence of mantle cell lymphoma cells.

B. Sander, M. Björkholm, Dawei Xu, 2021, Prostaglandins & other lipid mediators.

Leukotrienes stimulate initiation of DNA synthesis in cultured arterial smooth muscle cells.

J. Thyberg, L. Palmberg, H. Claésson, 1987, Journal of cell science.

Selenite incubated with NADPH and mammalian thioredoxin reductase yields selenide, which inhibits lipoxygenase and changes the electron spin resonance spectrum of the active site iron.

A. Holmgren, H. Claésson, S. Kuprin, 1996, Biochemistry.

Expression of cyclo-oxygenase-2 in human atherosclerotic carotid arteries.

H. Claésson, G. Hansson, J. Swedenborg, 2000, European Journal of Vascular and Endovascular Surgery.

On the expression of cytosolic calcium‐independent phospholipase A2 (88 kDa) in immature and mature myeloid cells and its role in leukotriene synthesis in human granulocytes

M. Björkholm, H. Claésson, P. Larsson Forsell, 1998, FEBS letters.

Expression of phospholipase A2 isoforms in human normal and atherosclerotic arterial wall.

U. Hedin, H. Claésson, L. Elinder, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Leukotriene B4 plays a pivotal role in CD40-dependent activation of chronic B lymphocytic leukemia cells.

E. Klein, M. Björkholm, S. Feltenmark, 2004, Blood.

Leukotriene B 4 plays a pivotal role in CD40-dependent activation of chronic B lymphocytic leukemia cells

E. Klein, M. Björkholm, S. Feltenmark, 2004 .

Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome

O. Werz, Markus Werner, A. Koeberle, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets.

J. Lindgren, H. Kindahl, S. Hammarström, 1980, Advances in prostaglandin and thromboxane research.

Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes.

B. Sander, M. Björkholm, O. Rådmark, 2015, Prostaglandins, leukotrienes, and essential fatty acids.

High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes

Birgitta Sander, B. Sander, J. Flygare, 2009, BMC Immunology.

The Influence of Aspirin on Release of Eoxin C4, Leukotriene C4 and 15-HETE, in Eosinophilic Granulocytes Isolated from Patients with Asthma

S. Dahlén, B. Dahlén, K. Daham, 2013, International Archives of Allergy and Immunology.

Preferential Generation of 15‐HETE‐PE Induced by IL‐13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells

S. Wenzel, H. Claésson, V. O’Donnell, 2017, American journal of respiratory cell and molecular biology.

Endogenous prostaglandin E2 production inhibits proliferation of polyoma virus-transformed 3T3 cells: correlation with cellular levels of cyclic AMP.

J. Lindgren, H. Claésson, S. Hammarström, 1980, Advances in prostaglandin and thromboxane research.

Inhibition of prostaglandin synthesis in mouse 3T3 fibroblasts and human platelets by substituted phenols.

J. Lindgren, H. Claésson, S. Hammarström, 1977, Prostaglandins.

Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma

A. Porwit, P. Murray, M. Björkholm, 2008, International journal of cancer.

Inhibitors of arachidonic acid metabolism reduce DNA and nuclear fragmentation induced by TNF plus cycloheximide in U937 cells

S. Orrenius, P. Jakobsson, S. Feltenmark, 1997, Cell Death and Differentiation.

Human 15‐lipoxygenase‐1 is a regulator of dendriticcell spreading and podosome formation

M. Ekberg, M. Björkholm, Dawei Xu, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation.

M. Ekberg, M. Björkholm, Dawei Xu, 2016 .

Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling.

J. Erjefält, C. Andersson, A. Hällgren, 2008, American journal of respiratory cell and molecular biology.

Cloning, purification and characterization of non-human primate 12/15-lipoxygenases.

L. Backman, H. Claésson, M. Johannesson, 2010, Prostaglandins, leukotrienes, and essential fatty acids.

Endogenous prostaglandin E2 synthesis inhibits growth of polyoma virus-transformed 3T3 fibroblasts.

J. Lindgren, H. Claésson, S. Hammarström, 1979, Experimental cell research.

Prostaglandin E2 production in 3T3 cells transformed by polyoma virus raises the intracellular adenosine 3':5'-monophosphate levels.

S. Hammarström, J. Lindgren, H. Claésson, 1977, European journal of biochemistry.

Expression of Mast Cell Tryptases in Hodgkin and Reed‐Sternberg (HRS) Cells

G. Nilsson, H. Claésson, I. Glimelius, 2007, Scandinavian journal of immunology.

Expression of 5-lipoxygenase and biosynthesis of leukotriene B4 in human monomorphonuclear leukocytes.

D. Steinhilber, B. Samuelsson, P. Jakobsson, 1993, Journal of lipid mediators.

On the interrelationship of prostaglandin endoperoxide G2 and cyclic nucleotides in platelet function.

C. Malmsten, H. Claésson, H. Claesson, 1977, European journal of biochemistry.

Stimulation of human leukocyte degranulation by leukotriene B4 and its ω‐oxidized metabolites

B. Samuelsson, J. Lindgren, C. Malmsten, 1981 .

Stimulation of human leukocyte degranulation by leukotriene B4 and its omega-oxidized metabolites.

B. Samuelsson, J. Lindgren, C. Malmsten, 1981, FEBS letters.

Activation of innate immunity by the leukotriene B 4 inhibits EBV induced B-cell transformation in cord-blood derived mononuclear cultures.

E. Klein, H. Claésson, Anquan Liu, 2008, Immunology letters.

Suppression of leukotriene synthesis in human leukocytes by a urea extract of Bordetella pertussis: evidence for mediation by adenylate cyclase toxin.

B. Gustafsson, F. Green, H. Claesson, 1988, Toxicon : official journal of the International Society on Toxinology.

Ethanol-enhanced transmembrane penetration of arachidonic acid and activation of the 5-lipoxygenase pathway in human leukocytes.

H. Claésson, F. A. Green, F. Green, 1986, Biochemical and biophysical research communications.

COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells.

G. Nilsson, M. Hamberg, S. Dahlén, 2021, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Interleukin-13 stimulation of the mediastinal B-cell lymphoma cell line Karpas-1106P induces a phenotype resembling the Hodgkin lymphoma cell line L1236.

M. Björkholm, H. Claésson, F. Schain, 2010, Experimental hematology.

Hodgkin Reed–Sternberg cells express 15‐lipoxygenase‐1 and are putative producers of eoxins in vivo

A. Porwit, M. Björkholm, S. Feltenmark, 2008, The FEBS journal.

Cysteinyl leukotrienes enhance growth of human airway epithelial cells.

R. Grafström, H. Claésson, G. Leikauf, 1990, The American journal of physiology.

Relationship of cyclic-AMP levels in leukotriene B4-stimulated leukocytes to lysosomal enzyme release and the generation of superoxide anions.

H. Claésson, S. Feinmark, H. Claesson, 1984, Biochimica et biophysica acta.

Interleukin-4-Mediated 15-Lipoxygenase-1 Trans-Activation Requires UTX Recruitment and H3K27me3 Demethylation at the Promoter in A549 Cells

C. Liu, M. Björkholm, Dawei Xu, 2014, PloS one.

Opsonized bacteria stimulate leukotriene synthesis in human leukocytes.

J. Lindgren, H. Claésson, B. Gustafsson, 1985, Biochimica et biophysica acta.

Stimulation of human myelopoiesis by leukotriene B4.

G. Gahrton, H. Claésson, N. Dahlberg, 1985, Biochemical and biophysical research communications.

Inhibition of intradental nerve excitability by leukotriene B4 and C4.

H. Claésson, B. Gazelius, B. Odlander, 1984, Acta physiologica Scandinavica.

Mitogenic Effects of Eicosanoids in Human Airway Epithelial Cells

H. Claésson, G. Leikauf, C. A. Doupnik, 1991 .

Studies on Expression and Regulation of 5-Lipoxygenase in Human B Lymphocytes

D. Steinhilber, B. Samuelsson, P. Jakobsson, 1993 .

Effects of 1-chloro-2,4,6-trinitrobenzene on 5-lipoxygenase activity and cellular leukotriene synthesis.

O. Rådmark, J. Lindgren, T. Hammarberg, 1998, Biochemical pharmacology.

On the mechanism of induction of DNA synthesis in cultured arterial smooth muscle cells by leukotrienes. Possible role of prostaglandin endoperoxide synthase products and platelet-derived growth factor.

J. Thyberg, L. Palmberg, J. Lindgren, 1991, Journal of cell science.