Aya Tanatani

发表

Foldamers as dynamic receptors: probing the mechanism of molecular association between helical oligomers and rodlike ligands.

T. S. Hughes, Jeffrey S. Moore, A. Tanatani, 2002, Angewandte Chemie.

Accessing Improbable Foldamer Shapes with Strained Macrocycles

I. Huc, Y. Ferrand, M. Kawahata, 2021, Chemistry.

Aromatic β-sheet foldamers based on tertiary squaramides.

P. Mayer, I. Huc, Joan Atcher, 2019, Chemical communications.

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence.

H. Kagechika, T. Hirano, H. Masuno, 2011, Journal of medicinal chemistry.

Folding of a linear array of α-amino acids within a helical aromatic oligoamide frame.

I. Huc, B. Kauffmann, V. Maurizot, 2013, Journal of the American Chemical Society.

Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide.

Y. Hashimoto, H. Miyachi, H. Sano, 2005, Bioorganic & medicinal chemistry.

Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore

H. Kagechika, Mari Ishigami‐Yuasa, S. Fujii, 2020, International journal of molecular sciences.

Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents.

H. Kagechika, Ayumi Yamada, Mari Ishigami‐Yuasa, 2018, Bioorganic & medicinal chemistry.

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

K. Yura, Y. Hashimoto, H. Kagechika, 2015, European journal of medicinal chemistry.

Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands.

M. Makishima, Y. Hashimoto, K. Wakabayashi, 2006, Bioorganic & medicinal chemistry letters.

Absolute helical arrangement of stacked benzene rings: heterogeneous double-helical interaction comprising a hydrogen-bonding belt and an offset parallel aromatic-aromatic-interaction array.

Tsutomu Yokozawa, T. Yokozawa, I. Azumaya, 2004, Angewandte Chemie.

4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor.

Y. Hashimoto, K. Wakabayashi, H. Miyachi, 2008, Bioorganic & medicinal chemistry.

Aromatic layered guanidines bind sequence-specifically to DNA minor groove with precise fit

N. Tomioka, A. Itai, Y. Hashimoto, 1998 .

Crystal Engineering of N,N′-Diphenylurea Compounds Featuring Phenyl–Perfluorophenyl Interaction

H. Kagechika, H. Masu, Ai Ito, 2017 .

Conformational properties of aromatic multi-layered and helical oligoureas and oligoguanidines

A. Tanatani, Mayumi Kudo, Aya Tanatani, 2015 .

Structures of N , N ′-bis(1,2-dicarba- closo -dodecaboran-1-yl)phenylureas: building blocks for carborane-containing macromolecules

H. Kagechika, Y. Endo, K. Yamaguchi, 2000 .

A CHIRAL N-METHYLBENZAMIDE : SPONTANEOUS GENERATION OF OPTICAL ACTIVITY

Shingo Nakayama, Kentaro Yamaguchi, Koichi Shudo, 1999 .

Helical aromatic urea and guanidine

H. Kagechika, K. Shudo, I. Azumaya, 1997 .

(Cis)-PREFERENCE OF N, N'-DIMETHYL-N, N'-DIPHENYLGUANIDINE AND THE GUANIDINIUM SALT. CONSTRUCTION OF WATER-SOLUBLE AROMATIC LAYERED STRUCTURE

H. Kagechika, K. Shudo, I. Azumaya, 1996 .

Spontaneous resolution of aromatic sulfonamides: effective screening method and discrimination of absolute structure.

H. Kagechika, I. Azumaya, M. Uchiyama, 2006, Organic letters.

Solvent-dependent conformational and fluorescence change of an N-phenylbenzohydroxamic acid derivative bearing two pyrene moieties

H. Kagechika, T. Hirano, I. Azumaya, 2012 .

Solvent-Dependent Conformational Switching of N-Phenylhydroxamic Acid and Its Application in Crystal Engineering

H. Kagechika, I. Azumaya, H. Masu, 2006 .

Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists

N. Ito, T. Ikura, H. Kagechika, 2019 .

Molecular construction based on icosahedral carboranes and aromatic N,N′-dimethylurea groups. Aromatic layered molecules and a transition metal complex

H. Kagechika, Y. Endo, K. Yamaguchi, 2002 .

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane.

N. Ito, H. Kagechika, M. Shimizu, 2011, Journal of the American Chemical Society.

Specific nonpeptide inhibitors of puromycin-sensitive aminopeptidase with a 2,4(1H,3H)-quinazolinedione skeleton.

Y. Hashimoto, K. Nagasawa, H. Kakuta, 2003, Chemical & pharmaceutical bulletin.

An N-Cyanoamide Derivative of Lithocholic Acid Co-Operates with Lysophosphatidic Acid to Promote Human Osteoblast (MG63) Differentiation

H. Kagechika, J. Mansell, J. P. Mansell, 2023, Biomolecules.

Development of novel lithocholic acid derivatives as vitamin D receptor agonists.

N. Ito, T. Ikura, H. Kagechika, 2019, Bioorganic & medicinal chemistry.

Nuclear Receptor Drug Discovery

H. Kagechika, A. Tanatani, Aya Tanatani, 2008 .

Practical synthesis and evaluation of the biological activities of 1alpha,25-dihydroxyvitamin D3 antagonists, 1alpha,25-dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis.

Y. Hashimoto, K. Nagasawa, Y. Kato, 2006, Journal of medicinal chemistry.

N-phenylphthalimide-type cyclooxygenase (COX) inhibitors derived from thalidomide: substituent effects on subtype selectivity.

Y. Hashimoto, H. Miyachi, H. Sano, 2004, Chemical & pharmaceutical bulletin.

Cyclooxygenase inhibitors derived from thalidomide.

Y. Hashimoto, H. Kagechika, K. Nagasawa, 2003, Chemical & pharmaceutical bulletin.

Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl-shaped conformation in the crystal and solution states

H. Kagechika, I. Azumaya, H. Masu, 2010 .

Artificial water channels for desalination based on oligourea foldamer self-assembly

Aya Tanatani, Fumi Takeda, 2023, Chem.

Development of Retinoic Acid Receptor Antagonists Bearing Trans-Sf4-Alkynyl Structure as a Linear Linker

H. Kagechika, Shuichi Mori, A. Tanatani, 2022, SSRN Electronic Journal.

Solid-Phase Synthesis of Water-Soluble Helically Folded Hybrid α-Amino Acid/Quinoline Oligoamides.

Xiaobo Hu, I. Huc, A. Tanatani, 2016, The Journal of organic chemistry.

Unusual conformational preference of an aromatic secondary urea: solvent-dependent open-closed conformational switching of N,N'-bis(porphyrinyl)urea.

H. Kagechika, D. Hashizume, I. Azumaya, 2013, Chemical Communications.

The size-selective synthesis of folded oligomers by dynamic templation.

Jeffrey S. Moore, T. Nishinaga, A. Tanatani, 2002, Journal of the American Chemical Society.

Chain length-dependent affinity of helical foldamers for a rodlike guest.

Matthew J. Mio, J S Moore, Jeffrey S. Moore, 2001, Journal of the American Chemical Society.

Synthesis of porphyrinylamide and observation of N-methylation-induced trans–cis amide conformational alteration

H. Kagechika, D. Hashizume, I. Azumaya, 2013 .

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution.

H. Kagechika, T. Hirano, I. Azumaya, 2009, The Journal of organic chemistry.

Development of 1,3-diphenyladamantane derivatives as nonsteroidal progesterone receptor antagonists.

H. Kagechika, S. Fujii, Shuichi Mori, 2015, Bioorganic & medicinal chemistry.

Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein.

Y. Hashimoto, H. Koshino, T. Nakata, 2005, Chemistry.

Enantioselective total synthesis of batzelladine A.

Y. Hashimoto, K. Nagasawa, A. Tanatani, 2004, Angewandte Chemie.

Structural elucidation of foldamers with no long range conformational order.

I. Huc, H. Masu, V. Maurizot, 2014, Chemical communications.

Calix[3]amide-based anion receptors: high affinity for fluoride ions and a twisted binding model

H. Kagechika, I. Azumaya, M. Uchiyama, 2011 .

Synthesis of 1α,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1α,25-dihydroxyvitamin D3 antagonist

Y. Hashimoto, H. Koshino, Hisayoshi Kobayashi, 2004 .

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

Minoru Yoshida, H. Kagechika, A. Ito, 2016, Bioorganic & medicinal chemistry.

Phenylhomophthalimide-type NOS inhibitors derived from thalidomide.

Y. Hashimoto, H. Miyachi, H. Sano, 2004, Bioorganic & medicinal chemistry letters.

Redox-responsive conformational alteration of aromatic amides bearing N-quinonyl system

H. Kagechika, I. Azumaya, H. Masu, 2012 .

[Development of novel nuclear receptor ligands based on receptor-folding inhibition hypothesis].

A. Tanatani, Aya Tanatani, 2007, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor.

Y. Hashimoto, K. Nagasawa, T. Ishioka, 2003, Bioorganic & medicinal chemistry letters.

Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists

M. Makishima, N. Ito, H. Kagechika, 2022, Biomolecules.

Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.

N. Ito, H. Kagechika, Keiko Yamamoto, 2020, Journal of medicinal chemistry.

Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs.

H. Kagechika, T. Hirano, H. Masuno, 2014, Bioorganic & medicinal chemistry.

Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction

Y. Hashimoto, K. Nagasawa, A. Tanatani, 2004 .