Joan P. Graves

发表

Cloning of CYP2J2 gene and identification of functional polymorphisms.

H. Mohrenweiser, J. Liao, D. Zeldin, 2002, Molecular pharmacology.

Highly selective isolation of human DNAs from rodent-human hybrid cells as circular yeast artificial chromosomes by transformation-associated recombination cloning.

V. Larionov, M. Resnick, N. Kouprina, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

Samantha L. Hoopes, D. Zeldin, M. Edin, 2018, The Journal of Biological Chemistry.

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia‐reperfusion injury in isolated mouse heart

K. Tomer, O. Rønnekleiv, J. Foley, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension‐induced renal injury in mice

K. Tomer, O. Rønnekleiv, J. Foley, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop

S. Safe, Q. Zhong, Woosuk Kim, 2021, Nutrients.

sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae.

M. Fessler, Samantha L. Hoopes, D. Zeldin, 2021, The Journal of clinical investigation.

Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination.

X. Chen, J. Korenberg, V. Larionov, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms

T. Lu, Hon-chi Lee, D. Zeldin, 2006, The Journal of physiology.

Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2

D. Mansuy, D. Zeldin, P. Lafite, 2018, International journal of molecular sciences.

Enhancement of Cardiac L-Type Ca2+ Currents in Transgenic Mice with Cardiac-Specific Overexpression of CYP2J2

J. Falck, D. Zeldin, Yong-Fu Xiao, 2004, Molecular Pharmacology.

Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway

J. Foley, H. Rockman, L. Mao, 2004, Circulation research.

Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence.

J. Barrett, N. Kouprina, V. Larionov, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4

I. Cobos, J. Rubenstein, D. Stumpo, 2003, Development.

Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development

D. Stumpo, P. Blackshear, J. Collins, 2006, Journal of neurochemistry.

Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.

Wen‐Hui Wang, D. Lin, D. Zeldin, 2014, American journal of physiology. Renal physiology.

Electrophysiological Properties of Cardiomyocytes Isolated from CYP2J2 Transgenic Mice

D. Zeldin, Yong-Fu Xiao, J. A. Bradbury, 2007, Molecular Pharmacology.

Role of Soluble Epoxide Hydrolase in Postischemic Recovery of Heart Contractile Function

J. Falck, H. Rockman, D. Zeldin, 2006, Circulation research.

20-HETE Signals Through G-Protein–Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension

J. Falck, D. Zeldin, A. Gruzdev, 2017, Circulation research.

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2

K. Tomer, J. Falck, Samantha L. Hoopes, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities.

J. Goldstein, J. Foley, D. Zeldin, 2004, Molecular pharmacology.

Pharmacologic Inhibition of COX-1 and COX-2 in Influenza A Viral Infection in Mice

D. Zeldin, J. A. Bradbury, M. Carey, 2010, PloS one.

Regulation of T helper cell subsets by cyclooxygenases and their metabolites.

D. Zeldin, M. Edin, A. Gruzdev, 2013, Prostaglandins & other lipid mediators.

CYP eicosanoid pathway mediates colon cancer‐promoting effects of dietary linoleic acid

D. Zeldin, M. Edin, Jun Yang, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of B-type natriuretic peptide in epoxyeicosatrienoic acid-mediated improved post-ischaemic recovery of heart contractile function.

J. Falck, D. Zeldin, J. Seubert, 2009, Cardiovascular research.

Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids.

J. Falck, D. Zeldin, B. Hammock, 2012, Advances in bioscience and biotechnology.

Cyclooxygenase-2 inhibits T helper cell type 9 differentiation during allergic lung inflammation via down-regulation of IL-17RB.

C. Bortner, D. Zeldin, M. Edin, 2013, American journal of respiratory and critical care medicine.

Spontaneous Airway Hyperresponsiveness in Estrogen Receptor-α–deficient Mice

K. Korach, E. Gelfand, E. Jacobs, 2007 .

Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.

K. Korach, E. Gelfand, E. Jacobs, 2007, American journal of respiratory and critical care medicine.

Cyclooxygenase-1 Overexpression Decreases Basal Airway Responsiveness but Not Allergic Inflammation1

D. Morgan, J. Foley, D. Zeldin, 2006, The Journal of Immunology.

Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity.

J. Foley, D. Zeldin, J. A. Bradbury, 2009, American journal of physiology. Heart and circulatory physiology.

Overexpression of CYP 2 J 2 provides protection against doxorubicin-induced cardiotoxicity

J. Foley, D. Zeldin, J. A. Bradbury, 2009 .

Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts

D. Zeldin, I. Fleming, M. Edin, 2023, The Journal of biological chemistry.

Integrative Physiology 20-HETE Signals Through G-Protein–Coupled Receptor GPR75 (G q ) to Affect Vascular Function and Trigger Hypertension

D. Zeldin, A. Gruzdev, J. Falck, 2017 .

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

K. Tomer, J. Foley, J. Falck, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation.

K. Tomer, C. Bortner, D. Zeldin, 2011, American journal of respiratory and critical care medicine.

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation

Samantha L. Hoopes, D. Zeldin, M. Edin, 2015, Drug Metabolism and Disposition.

Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS‐induced inflammation and resolution in mice

D. Zeldin, M. Edin, F. Lih, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characterization of Four New Mouse Cytochrome P450 Enzymes of the CYP2J Subfamily

K. Tomer, D. Zeldin, M. Edin, 2013, Drug Metabolism and Disposition.

Regulation of mouse renal CYP2J5 expression by sex hormones.

K. Korach, D. Zeldin, J. A. Bradbury, 2004, Molecular pharmacology.

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function

D. Zeldin, M. Edin, F. Lih, 2020, The Journal of biological chemistry.

EPHX 1 Regulates EET Hydrolysis and Postischemic Recovery 1 Epoxide hydrolase 1 ( EPHX 1 ) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

Samantha L. Hoopes, D. Zeldin, M. Edin, 2018 .

Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis

D. Zeldin, M. Edin, A. Gruzdev, 2017, Drug Metabolism and Disposition.

Overexpression of soluble epoxide hydrolase reduces post-ischemic recovery of cardiac contractile function.

D. Zeldin, M. Edin, F. Lih, 2024, Biochemical pharmacology.

Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS‐CoV‐2‐infected mice

D. Zeldin, M. Edin, F. Lih, 2024, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased blood pressure in mice lacking cytochrome P450 2J5

K. Korach, D. Zeldin, J. F. Couse, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

Samantha L. Hoopes, D. Zeldin, M. Edin, 2017, PloS one.