Kieran Wynne

The Extracellular Matrix Environment of Clear Cell Renal Cell Carcinoma Determines Cancer Associated Fibroblast Growth

Leif Oxburgh, S. Sims-Lucas, J. Coburn, 2021, Cancers.

Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib

W. Kolch, D. Matallanas, A. Kriegsheim, 2023, Cancers.

Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis

C. Behl, S. Keely, K. Wynne, 2017, Scientific Reports.

Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes

Z. Giricz, P. Ferdinandy, D. Matallanas, 2023, Open research Europe.

Investigating serum extracellular vesicles in Cystic Fibrosis.

S. Carter, E. Dillon, J. Coppinger, 2023, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells

C. Kiel, S. Catozzi, K. Wynne, 2022, bioRxiv.

Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells.

Oleksii S. Rukhlenko, Nora Rauch, T. Sevrin, 2024, Cell reports.

Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles

Z. Giricz, D. Matallanas, E. Buzás, 2024, Scientific reports.