Huijing Xia

发表

Neuronal over-expression of ACE2 protects brain from ischemia-induced damage

Shuzhen Chen, Jinju Wang, Xiaotang Ma, 2014, Neuropharmacology.

Angiotensin‐converting enzyme 2 in the brain: properties and future directions

E. Lazartigues, H. Xia, Huijing Xia, 2008, Journal of neurochemistry.

Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE−/− Mice: Effects on eNOS and Oxidative Stress

A. Boulares, A. Kaye, M. Bonini, 2009, PloS one.

Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension

Kavaljit H. Chhabra, S. Sriramula, E. Lazartigues, 2013, Circulation research.

α-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17.

E. Lazartigues, H. Xia, T. M. de Queiroz, 2015, American journal of physiology. Heart and circulatory physiology.

Clinical Relevance and Role of Neuronal AT1 Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension

S. Sriramula, L. Moreno-Walton, Jiaxi Xu, 2017, Circulation research.

Angiotensin-Converting Enzyme 2 Overexpression in the Subfornical Organ Prevents the Angiotensin II–Mediated Pressor and Drinking Responses and Is Associated With Angiotensin II Type 1 Receptor Downregulation

Eric Lazartigues, Guangyu Wu, E. Lazartigues, 2008, Circulation research.

Angiotensin II Type 1 Receptor–Mediated Reduction of Angiotensin-Converting Enzyme 2 Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice

E. Lazartigues, H. Xia, Yumei Feng, 2009, Hypertension.

Pituitary adenylate cyclase-activating polypeptide (PACAP) protects against mitoxantrone-induced cardiac injury in mice

D. Coy, K. Varner, H. Xia, 2017, Peptides.

Angiotensin‐converting enzyme 2: a new target for neurogenic hypertension

R. Santos, E. Lazartigues, H. Xia, 2010, Experimental physiology.

Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension

R. Santos, C. Sigmund, C. Halabi, 2010, Circulation research.

The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs.

Kavaljit H. Chhabra, E. Lazartigues, H. Xia, 2013, Biochimica et biophysica acta.

ACE2-Mediated Reduction of Oxidative Stress in the Central Nervous System Is Associated with Improvement of Autonomic Function

L. Navar, E. Lazartigues, H. Xia, 2011, PloS one.

Angiotensin Converting Enzyme 2/Ang‐(1–7)/Mas Axis Protects Brain from Ischemic Injury with a Tendency of Age‐dependence

Shuzhen Chen, E. Lazartigues, H. Xia, 2014, CNS neuroscience & therapeutics.

Brain ACE2 overexpression reduces DOCA‐salt hypertension independently of endoplasmic reticulum stress (875.3)

I. Mungrue, S. Sriramula, E. Lazartigues, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Brain ACE 2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress

I. Mungrue, S. Sriramula, E. Lazartigues, 2015 .

Brain-Targeted Angiotensin-Converting Enzyme 2 Overexpression Attenuates Neurogenic Hypertension by Inhibiting Cyclooxygenase-Mediated Inflammation

S. Sriramula, E. Lazartigues, H. Xia, 2015, Hypertension.

brain of rabbits with pacing-induced heart failure Exercise training normalizes ACE and ACE2 in the

H. Middlekauff, Matthew R. Deshotels, C. Negrão, 2015 .

High-fat diet-induced glucose dysregulation is independent of changes in islet ACE2 in mice.

Kavaljit H. Chhabra, E. Lazartigues, H. Xia, 2016, American journal of physiology. Regulatory, integrative and comparative physiology.

Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent Mechanism

Matthew R. Deshotels, S. Sriramula, E. Lazartigues, 2014, Hypertension.

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

J. Pfeilschifter, D. Lefer, H. Xia, 2020, Journal of the American Heart Association.

Environmentally Persistent Free Radicals Cause Apoptosis in HL-1 Cardiomyocytes

K. Varner, H. Xia, G. Chuang, 2016, Cardiovascular Toxicology.

Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model.

Ravi B. Patel, D. Lefer, H. Xia, 2023, Journal of the American Heart Association.

Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney.

D. Lefer, K. Varner, H. Xia, 2017, Journal of the American College of Cardiology.

Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice Angiotensin II Type 1 Receptor-Mediated Reduction of Angiotensin-Converting Enzyme 2

C. Gharib, E. Lazartigues, H. Xia, 2009 .

Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction

J. Zheng, J. Olson, Shuzhen Chen, 2014, Neuroscience.

Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice.

Kavaljit H. Chhabra, E. Lazartigues, H. Xia, 2013, American journal of physiology. Endocrinology and metabolism.

Angiotensin Converting Enzyme 2/Ang‐(1–7)/Mas Axis Protects Brain from Ischemic Injury with a Tendency of Age‐dependence

Shuzhen Chen, E. Lazartigues, Jin-ju Wang, 2014, CNS neuroscience & therapeutics.

Angiotensin I–Converting Enzyme Type 2 (ACE2) Gene Therapy Improves Glycemic Control in Diabetic Mice

A. Boulares, E. Lazartigues, H. Xia, 2010, Diabetes.

Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.

T. Goodchild, Kyle B. LaPenna, Timothy D Allerton, 2024, British journal of pharmacology.

Hydrogen Sulfide Modulates Endothelial–Mesenchymal Transition in Heart Failure

J. Pfeilschifter, A. Papapetropoulos, D. Lefer, 2022, Circulation research.

Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure

N. Nagahara, J. Calvert, D. Lefer, 2022, Circulation research.