Philippe Nuhant

发表

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.

David C. Wood, K. Fennell, R. Kurumbail, 2018, Journal of medicinal chemistry.

Visible-Light-Driven Photocatalytic Initiation of Radical Thiol-Ene Reactions Using Bismuth Oxide.

Betsy S. Pierce, J. Mousseau, R. Robinson, 2015, Organic letters.

Campaign to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR)

Scott A. Busby, Ruben D. Garcia-Ordonez, P. Griffin, 2011 .

Enantio- and diastereoselective synthesis of (E)-1,5-syn-diols: application to the synthesis of the C(23)-C(40) fragment of tetrafibricin.

W. Roush, R. Lira, P. Nuhant, 2011, Organic letters.

Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ.

P. Griffin, Naresh Kumar, M. Cameron, 2010, ACS chemical biology.

Access to Highly Substituted 7-Azaindoles from 2-Fluoropyridines via 7-Azaindoline Intermediates.

J. Mousseau, Alpay Dermenci, C. Allais, 2015, Organic letters.

Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand

Dušica Vidović, William R. Roush, Philippe Nuhant, 2011, Nature.

Synthesis of ( R )- and ( S )-α-trifluoromethyl propanoic acids via asymmetric hydrogenation followed by salt resolution

N. Sach, O. Fadeyi, R. Unwalla, 2016 .

Modular radical cross-coupling with sulfones enables access to sp3-rich (fluoro)alkylated scaffolds

Lijie Sun, J. Mousseau, P. Baran, 2018, Science.

Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists.

F. Vajdos, M. Schnute, M. Vazquez, 2023, ACS medicinal chemistry letters.

Practical Kilogram Synthesis of (S)-1-Benzyl-4-Bromo-3-Methyl-1,2,3,6-Tetrahydropyridine

N. Sach, Ming Z. Chen, Vince M. Lombardo, 2021, Organic Process Research & Development.

Enhancement of 5-aminopenta-2,4-dienals electrophilicity via activation by O,N-bistrifluoroacetylation. application to an N-acyl Pictet-Spengler reaction.

C. Marazano, P. Nuhant, B. Delpech, 2009, The Journal of organic chemistry.

Further insight from model experiments into a possible scenario concerning the origin of manzamine alkaloids.

T. Nguyen, M. Bénéchie, C. Marazano, 2008, Angewandte Chemie.

Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine.

W. Roush, C. Allais, P. Nuhant, 2013, Angewandte Chemie.

Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.

N. Sach, Y. M. Fobian, Chulho Choi, 2017, Angewandte Chemie.

Electrochemically Enabled Chan-Lam Couplings of Aryl Boronic Acids and Anilines.

Timothy J Senter, P. Nuhant, Zachary J Gale-Day, 2019, Organic letters.

C-H Functionalization of Heteroarenes Using Unactivated Alkyl Halides through Visible-Light Photoredox Catalysis under Basic Conditions.

P. Nuhant, M. Boyd, Noah B Bissonnette, 2018, The Journal of organic chemistry.

Synthesis of Polyprenylated Benzoylphloroglucinols by Regioselective Prenylation of Phloroglucinol in an Aqueous Medium

C. Marazano, P. Nuhant, B. Delpech, 2008 .

Synthetic Studies Towards Bridgehead Diprenyl‐Substituted Bicyclo[3.3.1]nonane‐2,9‐diones as Models for Polyprenylated Acylphloroglucinol Construction

T. Pouplin, C. Marazano, P. Nuhant, 2007 .

Alpha,alpha'-annulation of 2,6-prenyl-substituted cyclohexanone derivatives with malonyl chloride: application to a short synthesis of (+/-)-clusianone. Formation and rearrangement of a biogenetic-like intermediate.

T. Pouplin, C. Marazano, P. Nuhant, 2007, Organic letters.

Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist.

P. Griffin, D. Kojetin, Naresh Kumar, 2011, ACS chemical biology.

Development of a Double Allylboration Reagent Targeting 1,5-syn-(E)-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin.

W. Roush, R. Lira, P. Nuhant, 2011, Tetrahedron.