Florence O. McCarthy

发表

Local bacteria affect the efficacy of chemotherapeutic drugs

G. Reid, W. Byrne, M. Tangney, 2015, Scientific Reports.

Synthetic routes to campesterol and dihydrobrassicasterol: a first reported synthesis of the key phytosterol dihydrobrassicasterol

A. Maguire, N. O'Brien, F. McCarthy, 2012 .

30th Annual GP2A Medicinal Chemistry Conference

M. Meegan, N. O’Boyle, A. Sasse, 2023, Pharmaceuticals.

29th Annual GP2A Medicinal Chemistry Conference

N. O’Boyle, F. Giuntini, S. E. Matthews, 2021, Pharmaceuticals.

Isolation, biological activity and synthesis of the natural product ellipticine and related pyridocarbazoles

Charlotte M. Miller, F. McCarthy, Florence O. McCarthy, 2012 .

Emerging Targets in the Bioactivity of Ellipticines and Derivatives

Charlotte M. Miller, F. McCarthy, Fiona M. Deane, 2013 .

Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics.

Blair F. Johnston, S. Mackay, F. McCarthy, 2007, Bioorganic & medicinal chemistry.

Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family.

J. A. Spicer, P. Ellis, W. Denny, 2016, Journal of medicinal chemistry.

Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products

A. Maguire, N. O'Brien, E. Ryan, 2005, British Journal of Nutrition.

Oxidation of sitosterol and transport of its 7-oxygenated products from different tissues in humans and ApoE knockout mice

Charlotte M. Miller, U. Laufs, D. Lütjohann, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

7β-Hydroxysitosterol crosses the blood–brain barrier more favored than its substrate sitosterol in ApoE−/− mice

Charlotte M. Miller, U. Laufs, D. Lütjohann, 2015, Steroids.

Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice.

Charlotte M. Miller, U. Laufs, M. Böhm, 2015, Atherosclerosis.

Recent advances in Phytosterol Oxidation Products.

N. O'Brien, F. McCarthy, Y. O’Callaghan, 2014, Biochemical and biophysical research communications.

Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line.

A. Maguire, N. O'Brien, D. A. Foley, 2010, Journal of agricultural and food chemistry.

Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives.

J. Kerry, A. Maguire, S. Hogan, 2005, Organic & biomolecular chemistry.

Synthesis, isolation and characterisation of beta-sitosterol and beta-sitosterol oxide derivatives.

J. Kerry, A. Maguire, S. Hogan, 2005, Organic and biomolecular chemistry.

Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells.

A. Maguire, N. O'Brien, F. McCarthy, 2013, Biochimie.

Synthesis of novel 3,4-diaryl-5-aminopyrazoles as potential kinase inhibitors

Michael M. Cahill, F. McCarthy, Larry T. Pierce, 2011 .

Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria.

M. Tangney, F. McCarthy, P. Lehouritis, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Computer simulations reveal a novel nucleotide-type binding orientation for ellipticine-based anticancer c-kit kinase inhibitors.

Charlotte M. Miller, Damien Thompson, F. McCarthy, 2008, Biochemistry.

A mechanistic investigation into the microbial chiral inversion of 2-arylpropionic acids using deuterated derivatives of 2-phenylpropionic acid

A. Lloyd, F. McCarthy, G. Hanlon, 1998 .

The impact of storage conditions upon gentamicin coated antimicrobial implants☆

A. Maguire, S. Lawrence, H. Moynihan, 2016, Journal of pharmaceutical analysis.

Isoquinolinequinone N-oxides as anticancer agents effective against drug resistant cell lines.

J. Glennon, F. McCarthy, S. Lawrence, 2020, Organic & biomolecular chemistry.

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition.

Michael M. Cahill, S. Ruchaud, F. McCarthy, 2018, Bioorganic & medicinal chemistry.

Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

F. Gouilleux, B. Baratte, F. McCarthy, 2021, Molecules.

Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.

A. Maguire, A. McCluskey, F. McCarthy, 2013, Organic & biomolecular chemistry.

Phytosterol Oxidation Products: Their Formation, Occurrence, and Biological Effects

A. Maguire, N. O'Brien, E. Ryan, 2009 .

Oxidized derivatives of dihydrobrassicasterol: cytotoxic and apoptotic potential in U937 and HepG2 cells.

A. Maguire, N. O'Brien, F. McCarthy, 2012, Journal of agricultural and food chemistry.

Synthesis and characterization of stigmasterol oxidation products.

A. Maguire, N. O'Brien, D. A. Foley, 2010, Journal of agricultural and food chemistry.

7-formyl-10-methylisoellipticine, a novel ellipticine derivative, induces mitochondrial reactive oxygen species (ROS) and shows anti-leukaemic activity in mice

T. Cotter, C. O’Driscoll, Jianfeng Guo, 2016, Investigational New Drugs.

Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells

Charlotte M. Miller, T. Cotter, C. Miller, 2014, Investigational New Drugs.

Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products

A. Maguire, N. O'Brien, E. Ryan, 2005, British Journal of Nutrition.