Phillip W. Hargrove

发表

The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number.

A. Nienhuis, D. Persons, E. Allay, 2003, Blood.

Gene transfer into hematopoietic cells

A. Nienhuis, E. Vanin, J. Bertran, 1997, Stem cells.

Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin.

J. Gray, D. Persons, T. Pestina, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.

S. Orkin, A. Nienhuis, N. Anagnou, 2011, Blood.

A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.

C. Barbas, U. Tschulena, A. Nienhuis, 2010, Blood.

Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells.

J. Gray, Cheng Cheng, G. Neale, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia

D. Srivastava, A. Nienhuis, D. Persons, 2004 .

Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells.

A. Nienhuis, T. Brent, B. Sorrentino, 2003, Blood.

High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.

T. Wolfsberg, A. Nguyen, J. Tisdale, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

primary human adult erythroblasts -globin gene promoters enhances fetal hemoglobin production in γ A zinc-finger transcriptional activator designed to interact with the

U. Tschulena, A. Nienhuis, D. Persons, 2011 .

Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood.

Jody A. Vandergriff, A. Nienhuis, D. Persons, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells.

J. Allay, D. Persons, E. Horwitz, 1999, Human gene therapy.

Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells

M. Weiss, D. Persons, A. Wilber, 2015, Molecular therapy. Methods & clinical development.

Potentially therapeutic levels of anti-sickling globin gene expression following lentivirus-mediated gene transfer in sickle cell disease bone marrow CD34+ cells.

Michael L Kaufman, D. Kohn, D. Persons, 2015, Experimental hematology.

Globin Lentiviral Vector Insertions Can Perturb the Expression of Endogenous Genes in β-thalassemic Hematopoietic Cells.

J. Gray, Cheng Cheng, G. Neale, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

High-level globin gene expression mediated by a recombinant adeno-associated virus genome that contains the 3' gamma globin gene regulatory element and integrates as tandem copies in erythroid cells.

A. Nienhuis, G. Kurtzman, E. Vanin, 1997, Blood.

In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma.

A. Davidoff, M. B. McCarville, Blair Hamner, 2007, Journal of pediatric surgery.

Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.

Perdeep K. Mehta, D. Persons, M. Nasimuzzaman, 2009, Blood.

Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins.

A. Nienhuis, J. Gray, D. Persons, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Behavioral and molecular effects of Ubtf knockout and knockdown in mice

Roderick T. Hori, M. LeDoux, T. Moss, 2022, Brain Research.