J. Luft

发表

The effect of particle design on cellular internalization pathways

Stephanie E. A. Gratton, J. DeSimone, M. Napier, 2008, Proceedings of the National Academy of Sciences.

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

Joseph M. DeSimone, Timothy J. Merkel, Andrew Z. Wang, 2011, Proceedings of the National Academy of Sciences.

Synthesis and Characterization of Cetuximab-Docetaxel and Panitumumab-Docetaxel Antibody-Drug Conjugates for EGFR-Overexpressing Cancer Therapy.

Dylan M Glatt, Shamit S. Prabhu, R. Mumper, 2018, Molecular pharmaceutics.

Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells

J. DeSimone, J. C. Luft, Paul M. Airs, 2015, PLoS neglected tropical diseases.

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation.

Joseph M DeSimone, Jillian L Perry, J. C. Luft, 2015, Nano letters.

Nanoparticulate immunotherapy for cancer.

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Role of Linker Length and Antigen Density in Nanoparticle Peptide Vaccine

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2019, ACS omega.

Synthesis and characterization of monodisperse uniformly shaped respirable aerosols

J. DeSimone, J. C. Luft, B. Maynor, 2013 .

The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.

Dylan M Glatt, R. Mumper, J. C. Luft, 2016, Molecular pharmaceutics.

Pulmonary Delivery of Nanoparticle-Bound Toll-Like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.

J. Ting, B. Gorentla, J. DeSimone, 2020, ACS nano.

RNA replicon delivery via lipid-complexed PRINT protein particles.

G. Owens, Jing Xu, J. DeSimone, 2013, Molecular pharmaceutics.

Metronomic Docetaxel in PRINT Nanoparticles and EZH2 Silencing Have Synergistic Antitumor Effect in Ovarian Cancer

A. Sood, G. Lopez-Berestein, S. Wu, 2014, Molecular Cancer Therapeutics.

Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance.

J. Ting, J. DeSimone, J. Bear, 2016, ACS nano.

Biodistribution and Trafficking of Hydrogel Nanoparticles in Adult Mosquitoes

I. Sánchez-Vargas, J. DeSimone, J. C. Luft, 2015, PLoS neglected tropical diseases.

Silylated precision particles for controlled release of proteins.

Ashish A. Pandya, Saad A. Khan, J. C. Luft, 2015, ACS applied materials & interfaces.

Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung.

J. DeSimone, J. C. Luft, C. Fromen, 2016, Molecular pharmaceutics.

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft.

M. Walsh, J. DeSimone, M. Napier, 2013, Nanomedicine : nanotechnology, biology, and medicine.

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases.

C. Anders, A. Deal, J. DeSimone, 2016, Nanomedicine.

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location.

J. DeSimone, C. Pecot, J. C. Luft, 2017, Nano letters.

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

C. Perou, David B. Darr, N. Sharpless, 2017, Nano letters.

Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung.

C. Fromen, Marc P. Kai, Tojan B Rahhal, 2016, Molecular pharmaceutics.

Zapped assembly of polymeric (ZAP) nanoparticles for anti-cancer drug delivery.

J. C. Luft, Stuart S. Dunn, M. Parrott, 2019, Nanoscale.

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs.

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2016, Molecular pharmaceutics.

Potent engineered PLGA nanoparticles by virtue of exceptionally high chemotherapeutic loadings.

J. DeSimone, M. Napier, J. C. Luft, 2011, Nano letters.

Nanoparticulate immunotherapy for cancer.

Chintan H. Kapadia, Shaomin Tian, Jillian L. Perry, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

J. DeSimone, J. C. Luft, Charles J. Bowerman, 2015, Bioorganic & medicinal chemistry.

Small Molecule Therapeutics Metronomic Docetaxel in PRINT Nanoparticles and EZH 2 Silencing Have Synergistic Antitumor Effect in Ovarian Cancer

A. Sood, G. Lopez-Berestein, S. Wu, 2014 .

Delivery of multiple siRNAs using lipid-coated PLGA nanoparticles for treatment of prostate cancer.

J. Rolland, M. Napier, P. Pohlhaus, 2012, Nano letters.

Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo.

J. DeSimone, J. C. Luft, J. Baryza, 2015, Molecular pharmaceutics.

Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle.

W. Zamboni, Amanda W. Keeler, Jillian L. Perry, 2015, Journal of controlled release : official journal of the Controlled Release Society.

New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis.

N. Maeda, J. DeSimone, J. C. Luft, 2020, Vascular pharmacology.

Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer

J. Yeh, J. DeSimone, J. C. Luft, 2018, Cancer Chemotherapy and Pharmacology.

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

C. Perou, David B. Darr, N. Sharpless, 2017, Nano letters.

Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma

J. Yeh, J. DeSimone, J. C. Luft, 2016, Proceedings of the National Academy of Sciences.

Design of Asymmetric Particles Containing a Charged Interior and a Neutral Surface Charge: Comparative Study on in Vivo Circulation of Polyelectrolyte Microgels

Jing Xu, Joseph M. DeSimone, Kai Chen, 2014, Journal of the American Chemical Society.

One-Step Syntheses of Photocurable Polyesters Based on a Renewable Resource

Devin G. Barrett, T. Merkel, M. Yousaf, 2010 .

Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production

Joseph M. DeSimone, David Shirvanyants, Sue J. Mecham, 2016, PloS one.

Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells.

J. DeSimone, J. C. Luft, C. Fromen, 2016, Nanomedicine : nanotechnology, biology, and medicine.

Formulation of High-Performance Dry Powder Aerosols for Pulmonary Protein Delivery

J. Luft, Erin M. Wilson, J. DeSimone, 2018, Pharmaceutical Research.

Rendering protein-based particles transiently insoluble for therapeutic applications.

Ashish A. Pandya, G. Owens, J. DeSimone, 2012, Journal of the American Chemical Society.

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses.

M. Miley, J. DeSimone, A. D. de Silva, 2018, Bioconjugate chemistry.

Towards programming immune tolerance through geometric manipulation of phosphatidylserine.

Patrick J. Short, J. Ting, J. DeSimone, 2015, Biomaterials.

A versatile acid-labile linker for antibody–drug conjugates

J. DeSimone, J. C. Luft, Z. Haroon, 2014 .

Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted Delivery

J. DeSimone, J. C. Luft, C. Fromen, 2015, Pharmaceutical Research.