Sandy Desrat

发表

Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A.

Loëtitia Favre, E. Jacquet, J. Bignon, 2018, European journal of medicinal chemistry.

Development of an efficient route toward meiogynin A-inspired dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins.

F. Roussi, S. Desrat, C. Remeur, 2015, Organic & biomolecular chemistry.

Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.

Loëtitia Favre, M. Raphaël, F. Roussi, 2014, Bioorganic & medicinal chemistry letters.

From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins.

F. Roussi, B. Iorga, V. Dumontet, 2014, Chemical communications.

NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.

S. Corvaisier, Loëtitia Favre, F. Roussi, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Synthesis and Anti-Leishmanial Properties of Quinolones Derived from Zanthosimuline

F. Roussi, M. Litaudon, F. Olivon, 2022, Molecules.

Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2.

J. Bignon, F. Roussi, M. Litaudon, 2020, Bioorganic & medicinal chemistry letters.

Searching for original natural products by molecular networking: detection, isolation and total synthesis of chloroaustralasines

Jean-Luc Wolfender, Marc Litaudon, David Touboul, 2018 .

Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL‐1

J. Bignon, E. Lescop, V. Guérineau, 2021, ChemMedChem.

Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.

B. Antonny, J. Bignon, J. Polidori, 2023, Journal of medicinal chemistry.

Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor

R. Gautier, B. Antonny, J. Bignon, 2020, The Journal of Biological Chemistry.

Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor

R. Gautier, B. Antonny, J. Bignon, 2019, bioRxiv.

Isolation of Picrotoxanes from Austrobuxus carunculatus Using Taxonomy-Based Molecular Networking.

P. Retailleau, F. Roussi, D. Touboul, 2020, Journal of natural products.

Characterization, Diversity, and Structure-Activity Relationship Study of Lipoamino Acids from Pantoea sp. and Synthetic Analogues

J. Wolfender, P. Allard, I. Dusfour, 2019, International journal of molecular sciences.

Ring-rearrangement metathesis of substituted dihydropyrans and dihydrofurans

S. Desrat, D. L. Nouen, T. Tschamber, 2011 .

Selectivity in the Intermolecular Diels-Alder Reaction of Conjugated Trienes: Experimental and Theoretical Approaches

F. Roussi, V. Gandon, S. Desrat, 2018, European Journal of Organic Chemistry.