Ramakrishna Edupuganti

发表

Synthesis and structural analyses of phenylethynyl-substituted tris(2-pyridylmethyl)amines and their copper(ii) complexes.

A. Ellington, V. Lynch, E. Anslyn, 2016, Dalton transactions.

Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitors.

Pengyu Y. Ren, K. Dalby, E. Anslyn, 2014, Bioorganic & medicinal chemistry.

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

Y. Qi, N. Gray, Tinghu Zhang, 2017, Oncogene.

A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib

T. Kaoud, K. Dalby, N. Ebelt, 2017, Oncotarget.

Using docking and alchemical free energy approach to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis

Pengyu Y. Ren, K. Dalby, Qiantaoa Wang, 2015, Front. Mol. Biosci..

Reversible Covalent Inhibition of eEF‐2K by Carbonitriles

Pengyu Y. Ren, T. Kaoud, Chunli Yan, 2014, Chembiochem : a European journal of chemical biology.

High-Throughput Screens for eEF-2 Kinase

K. Dalby, B. Ozpolat, W. Johnson, 2014, Journal of biomolecular screening.

Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

Pengyu Y. Ren, K. Tsai, Matthew Harger, 2019, Nature Communications.

Conformational preferences of substrates for human prolyl 4-hydroxylase.

R. Raines, R. Edupuganti, Kelly L. Gorres, 2008, Biochemistry.

Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine.

Pengyu Y. Ren, K. Tsai, T. Kaoud, 2015, ACS medicinal chemistry letters.

Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine.

Pengyu Y. Ren, K. Tsai, Chunli Yan, 2015, ACS medicinal chemistry letters.

Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.

R. Krug, E. Anslyn, J. Robertus, 2014, European journal of medicinal chemistry.

Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer

Diane D. Liu, G. Hortobagyi, Jian Wang, 2023, Cancer research communications.

Mechanistic studies on covalent assemblies of metal-mediated hemi-aminal ethers

K. Dalby, H. Jo, E. Anslyn, 2014, Chemical science.

Computational insights into the binding of IN17 inhibitors to MELK

Brandon D. Walker, Pengyu Y. Ren, Matthew Harger, 2019, Journal of Molecular Modeling.

Computational and Experimental Studies of Inhibitor Design for Aldolase A.

Pengyu Ren, Zhifeng Jing, Kevin N Dalby, 2019, The journal of physical chemistry. B.

Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.

Pengyu Y. Ren, K. Dalby, C. Bartholomeusz, 2017, Bioorganic & medicinal chemistry.

Asymmetric total synthesis of (S)-(+)-cocaine and the first synthesis of cocaine C-1 analogs from N-sulfinyl β-amino ester ketals.

F. A. Davis, R. Edupuganti, Naresh Theddu, 2010, Organic letters.

Asymmetric synthesis of substituted homotropinones from N-sulfinyl beta-amino ketone ketals. (-)-Euphococcinine and (-)-adaline.

F. A. Davis, Ramakrishna Edupuganti, 2010, Organic letters.

Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics.

R. Raines, M. Shoulders, P. Carroll, 2012, The Journal of organic chemistry.

Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines.

Michael J. Zdilla, R. Raines, M. Shoulders, 2011, The Journal of organic chemistry.

Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.

R. Liddington, G. Powis, K. Dalby, 2016, Cancer research.