Muhammet Tanc

发表

Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones

C. Supuran, H. Sakagami, H. Gul, 2016, Journal of enzyme inhibition and medicinal chemistry.

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

C. Supuran, C. Yamali, H. Sakagami, 2016, Journal of enzyme inhibition and medicinal chemistry.

The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes

C. Supuran, C. Yamali, H. Gul, 2016, Journal of enzyme inhibition and medicinal chemistry.

Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II

C. Supuran, H. Gul, M. Tanc, 2016, Journal of enzyme inhibition and medicinal chemistry.

3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII.

C. Supuran, C. Ghelardini, A. Angeli, 2017, Journal of medicinal chemistry.

α-Carbonic Anhydrases Possess Thioesterase Activity.

C. Supuran, A. Scozzafava, F. Carta, 2015, ACS medicinal chemistry letters.

Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2016, Bioorganic & medicinal chemistry.

Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII.

C. Supuran, M. Tanc, M. Kaya, 2018, Bioorganic chemistry.

Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers.

G. D. De Meyer, W. Martinet, A. Kurdi, 2019, Bioorganic chemistry.

5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.

C. Supuran, K. Tārs, M. Tanc, 2013, Bioorganic & medicinal chemistry.

Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.

C. Supuran, F. Carta, A. Nocentini, 2018, Chemistry.

6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.

C. Supuran, C. Ghelardini, L. di Cesare Mannelli, 2015, Journal of medicinal chemistry.

Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.

C. Supuran, M. Tanc, A. Grandane, 2015, Bioorganic & medicinal chemistry.

6‐Triazolyl‐Substituted Sulfocoumarins Are Potent, Selective Inhibitors of the Tumor‐Associated Carbonic Anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014 .

6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.

C. Supuran, M. Tanc, A. Grandane, 2014, Bioorganic & medicinal chemistry.

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2013, Bioorganic & medicinal chemistry.

Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases

C. Supuran, M. Tanc, S. Kalinin, 2016, Journal of enzyme inhibition and medicinal chemistry.

5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII.

C. Supuran, I. Juranić, B. Drakulić, 2015, Bioorganic & medicinal chemistry.

ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma

G. D. De Meyer, W. Martinet, S. Stroobants, 2021, Frontiers in Oncology.

Dominant behaviours in the expression of human carbonic anhydrase hCA I activity.

C. Supuran, J. Winum, M. Barboiu, 2014, Chemical communications.

A class of carbonic anhydrase I – selective activators

C. Supuran, I. Kocsis, M. Barboiu, 2016, Journal of enzyme inhibition and medicinal chemistry.

In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes

O. De Wever, A. Lambeir, I. De Meester, 2021, Frontiers in Chemistry.

Mechanisms of action of carbonic anhydrase inhibitors

A. Angeli, M. Tanc, M. Bozdağ, 2019, Carbonic Anhydrases.

Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors

C. Supuran, M. Tanc, S. Thibaudeau, 2015, Journal of enzyme inhibition and medicinal chemistry.

Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.

C. Supuran, H. Abdel‐Aziz, S. M. Abou-Seri, 2015, European journal of medicinal chemistry.

Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties.

C. Supuran, I. Gülçin, M. Topal, 2015, Journal of medicinal chemistry.

CO2-capture by engineered mammalian carbonic anhydrases

A. Nocentini, M. Tanc, Muhammet Tanc, 2019, Carbonic Anhydrases.

Effective Access to Multivalent Inhibitors of Carbonic Anhydrases Promoted by Peptide Bioconjugation.

C. Supuran, J. Winum, S. Ulrich, 2017, Chemistry.

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

C. Supuran, D. Vullo, I. Gülçin, 2013, Bioorganic & medicinal chemistry.

Synthesis and carbonic anhydrase inhibitory properties of amino acid – coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties

C. Supuran, M. Tanc, F. Küçükbay, 2016, Journal of enzyme inhibition and medicinal chemistry.

9,10‐Dibromo‐N‐aryl‐9,10‐dihydro‐9,10‐[3,4]epipyrroloanthracene‐12,14‐diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII

C. Supuran, H. Göksu, I. Gülçin, 2016, Archiv der Pharmazie.

Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates

C. Supuran, M. Tanc, F. Küçükbay, 2016, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.

C. Supuran, M. Tanc, M. Kaya, 2015, Bioorganic & medicinal chemistry.

Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.

C. Supuran, M. Kaya, Burak Aday, 2016, Bioorganic & medicinal chemistry.

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

C. Supuran, C. Yamali, H. Sakagami, 2016, Journal of enzyme inhibition and medicinal chemistry.

Multimeric xanthates as carbonic anhydrase inhibitors

C. Supuran, M. Tanc, S. Vincent, 2016, Journal of enzyme inhibition and medicinal chemistry.

Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties.

C. Supuran, F. Carta, M. Tanc, 2014, Bioorganic & medicinal chemistry.

Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.

C. Supuran, M. Tanc, S. Vincent, 2015, Organic & biomolecular chemistry.