Dennis Farrelly

Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice.

R. Gregg, W. Fenderson, Wen-pin Yang, 2006, Diabetes.

Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Michael Cap, R. Gregg, W. Fenderson, 2006 .

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

Richard D. Gregg, R. Gregg, S. Lira, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A rapid, homogeneous, fluorescence polarization binding assay for peroxisome proliferator-activated receptors alpha and gamma using a fluorescein-tagged dual PPARα/γ activator

R. Seethala, Rajasree Golla, Zhengping Ma, 2007 .

Expression of Human Hepatic Glucokinase in Transgenic Mice Liver Results in Decreased Glucose Levels and Reduced Body Weight

A. Treloar, C. Arbeeny, K. Mookhtiar, 1997, Diabetes.

Oligomerization States and Associations of Light-Harvesting Pigment-Protein Complexes of Rhodobacter sphaeroides As Analyzed by Lithium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

J. Sturgis, C. Hunter, R. Niederman, 1988 .

Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious glucose and lipid-lowering activities.

Weiqi Wang, A. Doweyko, W. Humphreys, 2005, Journal of medicinal chemistry.

Design, synthesis, and structure-activity relationships of piperidine and dehydropiperidine carboxylic acids as novel, potent dual PPARalpha/gamma agonists.

Litao Zhang, K. O'Malley, P. Cheng, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.

Wei Wang, Jonathan Lippy, Arthur M Doweyko, 2009, Bioorganic & medicinal chemistry letters.