Nichole E Lapointe

发表

A Novel MAPT Mutation, G55R, in a Frontotemporal Dementia Patient Leads to Altered Tau Function

M. Barcikowska, A. Barczak, S. Feinstein, 2013, PloS one.

Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure.

S. Feinstein, M. Bowers, Thanh D. Do, 2016, Analytical chemistry.

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.

S. Feinstein, N. Lapointe, S. Brady, 2013, Neurotoxicology.

Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease

R. Berry, V. Cryns, S. Lagalwar, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy

M. Mesulam, D. Dickson, E. Bigio, 2003, Acta Neuropathologica.

Tau Aggregation Propensity Engrained in Its Solution State

J. Shea, S. Feinstein, M. Bowers, 2015, The journal of physical chemistry. B.

The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity

A. Kozikowski, N. Lapointe, G. Pigino, 2009, Journal of neuroscience research.

Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly

S. Feinstein, N. Lapointe, L. Wilson, 2019, The Journal of Biological Chemistry.

Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy.

S. Feinstein, N. Lapointe, M. Jordan, 2021, Toxicology and applied pharmacology.

The neuroprotective peptide NAP does not directly affect polymerization or dynamics of reconstituted neural microtubules.

S. Feinstein, N. Lapointe, M. Jordan, 2010, Journal of Alzheimer's disease : JAD.

Axonal Transport Defects in Neurodegenerative Diseases

Yuyu Song, Scott T. Brady, Klaus-Armin Nave, 2009, The Journal of Neuroscience.

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

A. Andreadis, N. Lapointe, G. Pigino, 2012, Neurobiology of Aging.

βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel

N. Lapointe, M. Jordan, L. Wilson, 2017, Cancer Chemotherapy and Pharmacology.

Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.

J. Shea, S. Feinstein, M. Bowers, 2015, The journal of physical chemistry. B.

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

A. Andreadis, N. Lapointe, G. Pigino, 2011, The Journal of Neuroscience.

Tau isoform‐specific modulation of kinesin‐driven microtubule gliding rates and trajectories as determined with tau‐stabilized microtubules

B. S. Manjunath, Austin J. Peck, K. Rose, 2010, Cytoskeleton.

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.

R. Berry, V. Cryns, S. Lagalwar, 2003, Biochemistry.

Cinnamon extract inhibits tau aggregation associated with Alzheimer's disease in vitro.

D. Graves, N. Lapointe, J. Lew, 2009, Journal of Alzheimer's disease : JAD.

Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro.

A. Andreadis, N. Lapointe, P. Horowitz, 2009, Biochemistry.

Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action

R. Lal, S. Feinstein, M. Bowers, 2016, Journal of neurochemistry.

1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose Binds to the N-terminal Metal Binding Region to Inhibit Amyloid β-protein Oligomer and Fibril Formation.

J. Shea, S. Feinstein, M. Bowers, 2017, International journal of mass spectrometry.

Regulation and aggregation of intrinsically disordered peptides

J. Shea, S. Feinstein, N. Lapointe, 2015, Proceedings of the National Academy of Sciences.

Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose on Amyloid β25-35 Assembly.

J. Shea, S. Feinstein, M. Bowers, 2016, ACS chemical neuroscience.

Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels.

D. Eisenberg, R. Nelson, D. Teplow, 2016, Journal of the American Chemical Society.

Effects of pH and charge state on peptide assembly: the YVIFL model system.

J. Shea, S. Feinstein, M. Bowers, 2013, The journal of physical chemistry. B.

Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study.

J. Shea, S. Feinstein, M. Bowers, 2013, Physical chemistry chemical physics : PCCP.

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport Through a Tau-Dependent Mechanism Involving Activation of Axonal

A. Andreadis, N. Lapointe, G. Pigino, 2012 .

N-terminal fragments of tau inhibit full-length tau polymerization in vitro.

R. Berry, N. Lapointe, P. Horowitz, 2006, Biochemistry.

Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.

J. Shea, S. Feinstein, M. Bowers, 2015, The journal of physical chemistry. B.

Factors that drive peptide assembly and fibril formation: experimental and theoretical analysis of Sup35 NNQQNY mutants.

D. Teplow, S. Feinstein, M. Bowers, 2013, The journal of physical chemistry. B.

Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants

D. Eisenberg, M. Sawaya, D. Teplow, 2014, The journal of physical chemistry. B.

Digital quantification of neurite outgrowth and retraction by phase-contrast microscopy: A tau perspective.

S. Feinstein, L. Wilson, D. Proctor, 2017, Methods in cell biology.

Tau proteins harboring neurodegeneration-linked mutations impair kinesin translocation in vitro.

S. Feinstein, N. Lapointe, Elmer Guzman, 2014, Journal of Alzheimer's disease : JAD.