Antony D. Adamson

发表

Quantitative measurement of single cell dynamics.

David G Spiller, D. Spiller, M. White, 2012, Current opinion in biotechnology.

A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology

N. Hanley, A. Adamson, V. Mikol, 2019, Stem cell reports.

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression

D. Spiller, P. Paszek, D. Jackson, 2023, bioRxiv.

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System

D. Hume, Werner Müller, Kathleen Grabert, 2020, The Journal of Immunology.

Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment

G. Yeo, A. Coll, A. Adamson, 2019, Molecular metabolism.

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

A. Loudon, K. Strimmer, M. Hastings, 2022, eLife.

Adipocyte NR1D1 dictates adipose tissue expansion during obesity

Nicholas J. Barron, D. Bechtold, A. Loudon, 2021, eLife.

Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism

Nicholas J. Barron, D. Bechtold, A. Loudon, 2020, Proceedings of the National Academy of Sciences.

Adipocyte REVERBα dictates adipose tissue expansion during obesity

Nicholas J. Barron, D. Bechtold, A. Loudon, 2020 .

LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

D. Brough, N. Humphreys, R. Bryce, 2020, eLife.

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

M. Rattray, A. Morris, S. Eyre, 2019, Nature Communications.

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling

D. Hume, B. McColl, I. Vetter, 2022, Development.

CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

M. Guilliams, J. Grainger, J. Konkel, 2023, bioRxiv.

CRISPR-mediated knock-in in the mouse embryo using long single stranded DNA donors synthesised by biotinylated PCR.

Hayley Bennett, Elisa Aguilar-Martinez, A. Adamson, 2020, Methods.

ADAMTS10-mediated tissue disruption in Weill–Marchesani syndrome

R. Boot-Handford, C. Baldock, A. Godwin, 2018, Human molecular genetics.

A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations

D. Smedley, D. Sherwood, Eric Hastie, 2021, bioRxiv.

Multi-omics analysis in primary T cells elucidates mechanisms behind disease associated genetic loci

Carlo, M. Rattray, A. Barton, 2023, medRxiv.

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

Vasanthi Priyadarshini Gaddi, A. Morris, P. Gaffney, 2020, BMC Biology.

Simultaneous analysis of open chromatin, promoter interactions and gene expression in stimulated T cells implicates causal genes for rheumatoid arthritis

M. Rattray, A. Morris, S. Eyre, 2019, bioRxiv.

Chromatin-based techniques map DNA interaction landscapes in psoriasis susceptibility loci and highlight KLF4 as a target gene in 9q31

Vasanthi Priyadarshini Gaddi, A. Morris, P. Gaffney, 2019, bioRxiv.

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

Aidan R. O’Brien, W. R. Thompson, Kathryn E. Hentges, 2019, Genome Biology.

Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology

W. R. Thompson, Kathryn E. Hentges, A. Loudon, 2018, bioRxiv.

On demand expression control of endogenous genes with DExCon, DExogron and LUXon reveals differential dynamics of Rab11 family members

P. Caswell, A. Adamson, Jakub Gemperle, 2022, eLife.

LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation

D. Brough, N. Humphreys, R. Bryce, 2020, bioRxiv.

Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9

D. Hume, Kathleen Grabert, N. Humphreys, 2019, bioRxiv.

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

Claire V. Harper, Pawel Paszek, William Rowe, 2016, Nature Communications.

Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing

Anne V. McNamara, Julian R. E. Davis, D. Spiller, 2015, Molecular endocrinology.

Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling.

Claire V. Harper, S. Semprini, S. Friedrichsen, 2008, Endocrinology.

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

D. Spiller, M. White, R. Brignall, 2018, Science Signaling.

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

Claire V. Harper, Pawel Paszek, Lloyd Bridge, 2016, eLife.

Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling.

Julian R. E. Davis, Claire V. Harper, G. Nelson, 2006, Endocrinology.

BCL-3 Attenuation of TNFA Expression Involves an Incoherent Feed-Forward Loop Regulated by Chromatin Structure

D. Jackson, A. Adamson, T. Walker, 2013, PloS one.

Loss of PKCα increases arterial medial calcification in a uremic mouse model of chronic kidney disease

P. Withers, N. Humphreys, S. Francis, 2020, bioRxiv.

Extending the allelic spectrum at noncoding risk loci of orofacial clefting

A. Hoischen, J. Bowes, A. Buness, 2021, Human mutation.

Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice

A. Coll, N. Humphreys, A. Adamson, 2019, Endocrinology.