K. Johnson

发表

Classification and nomenclature of phencyclidine and sigma receptor sites

Kenneth M. Johnson, P. Contreras, R. Quirion, 1987, Trends in Neurosciences.

Postnatal Phencyclidine Administration Selectively Reduces Adult Cortical Parvalbumin-Containing Interneurons

Kenneth M. Johnson, Yan Xia, Cheng Z. Wang, 2008, Neuropsychopharmacology.

Linkage between phencyclidine (PCP) and N-methyl-d-aspartate (NMDA) receptors in the cerebellum

Kenneth M. Johnson, S. Yi, L. Snell, 1988, Brain Research.

A Combined Bioinformatics and Chemoinformatics Approach for Developing Asymmetric Bivalent AMPA Receptor Positive Allosteric Modulators as Neuroprotective Agents

Kenneth M. Johnson, B. Copits, Jia Zhou, 2013, ChemMedChem.

Effects of phencyclidine (PCP)-like drugs on turning behavior, 3H-dopamine uptake, and 3H-PCP binding

Kenneth M. Johnson, L. Snell, K. Johnson, 1985, Pharmacology Biochemistry and Behavior.

Phencyclidine: Effects on motor activity and brain biogenic amines in the guinea pig

M. B. Gordon, M. Ziegler, K. Johnson, 1978 .

Activation of dopamine D1 receptors blocks phencyclidine‐induced neurotoxicity by enhancing N‐methyl‐D‐aspartate receptor‐mediated synaptic strength

Kenneth M. Johnson, V. Neugebauer, N. Anastasio, 2009, Journal of neurochemistry.

Neuropsychological, Neurovirological and Neuroimmune Aspects of Abnormal GABAergic Transmission in HIV Infection

V. Neugebauer, B. Gelman, K. Jennings, 2016, Journal of Neuroimmune Pharmacology.

Prefrontal Dopaminergic and Enkephalinergic Synaptic Accommodation in HIV-associated Neurocognitive Disorders and Encephalitis

Kenneth M. Johnson, B. Gelman, K. Jennings, 2012, Journal of Neuroimmune Pharmacology.

The role of inflammation in brain cancer.

Kenneth M. Johnson, C. Conrad, James L. Sowers, 2014, Advances in experimental medicine and biology.

Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.

C. George, J. Flippen-Anderson, A. Kozikowski, 1998, Journal of medicinal chemistry.

Glycine potentiates N-methyl-d-aspartate-induced [3H]TCP binding to rat cortical membranes

Kenneth M. Johnson, L. Snell, R. S. Morter, 1987, Neuroscience Letters.

Atypical anti-schizophrenic drugs prevent changes in cortical N-methyl-d-aspartate receptors and behavior following sub-chronic phencyclidine administration in developing rat pups

Kenneth M. Johnson, N. Anastasio, K. Johnson, 2008, Pharmacology Biochemistry and Behavior.

The Role of Akt-GSK-3β Signaling and Synaptic Strength in Phencyclidine-Induced Neurodegeneration

Kenneth M. Johnson, Yan Xia, Gang Lei, 2008, Neuropsychopharmacology.

The Role of Caspase-3 Activation in Phencyclidine-Induced Neuronal Death in Postnatal Rats

Kenneth M. Johnson, Cheng Z. Wang, K. Johnson, 2007, Neuropsychopharmacology.

Structure-Directing Role of Organoamine Ligands in the Self-Assembly of Novel Bimetallic Oxides†

Christopher J. Warren, Kenneth M. Johnson, R. Haushalter, 1998 .

Regulation of NMDA-stimulated [ 14 C ]GABA and [ 3 H ]acetylcholine release by striatal glutamate and dopamine receptors

Kenneth M. Johnson, T. Hanania, K. Johnson, 1999, Brain Research.

A Two-Dimensional Network Constructed via Hydrogen-Bonded Cross-Linkages of Molybdenum Oxide Chains

Kenneth M. Johnson, J. Zubieta, R. Laduca, 1998 .

Regulation of nitric oxide synthase activity in cortical slices by excitatory amino acids and calcium

G. Lonart, S. Alagarsamy, K. Johnson, 1994, Journal of neuroscience research.

Blockade of Phencyclidine-Induced Cortical Apoptosis and Deficits in Prepulse Inhibition by M40403, a Superoxide Dismutase Mimetic

Kenneth M. Johnson, Jie Bao, J. West, 2003, Journal of Pharmacology and Experimental Therapeutics.

Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia

P. Shinnick‐Gallagher, J. Wiley, K. Johnson, 2001, Neuroscience.

The role of NMDA receptor upregulation in phencyclidine-induced cortical apoptosis in organotypic culture.

Kenneth M. Johnson, Cheng Z. Wang, Jared Fridley, 2005, Biochemical pharmacology.

Differential regulation of the NMDA receptor by acute and sub‐chronic phencyclidine administration in the developing rat

Kenneth M. Johnson, N. Anastasio, K. Johnson, 2008, Journal of neurochemistry.

DIFFERENTIAL ROLE OF NR2A AND NR2B NMDA RECEPTORS IN MEDIATING PHENCYCLIDINE-INDUCED PERINATAL NEURONAL APOPTOSIS AND BEHAVIORAL DEFICITS

Kenneth M. Johnson, N. Anastasio, Yan Xia, 2009 .

Differential effects of acute and subchronic administration on phencyclidine‐induced neurodegeneration in the perinatal rat

Kenneth M. Johnson, Cheng Z. Wang, K. Johnson, 2005, Journal of neuroscience research.

A pharmacological analysis of the effects of (+)-AJ 76 and (+)-UH 232 at release regulating pre- and postsynaptic receptors

A. Gifford, K. Johnson, 1993 .

Chronic cocaine treatment impairs the regulation of synaptosomal 3H-DA release by D2 autoreceptors

Kenneth M. Johnson, S. Yi, K. Johnson, 1990, Pharmacology Biochemistry and Behavior.

α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazoleproprionic acid receptor activation protects against phencyclidine‐induced caspase‐3 activity by activating voltage‐gated calcium channels

Kenneth M. Johnson, J. Timpe, Cheng Z. Wang, 2014, Journal of neuroscience research.

Brain-derived neurotrophic factor prevents phencyclidine-induced apoptosis in developing brain by parallel activation of both the ERK and PI-3K/Akt pathways

Kenneth M. Johnson, Yan Xia, N. Anastasio, 2010, Neuropharmacology.

Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit

Kenneth M. Johnson, G. Hillman, T. Hanania, 1999, Synapse.

Traumatic brain injury reduces hippocampal high-affinity [3H]choline uptake but not extracellular choline levels in rats

C. Dixon, J. S. Bergmann, J. Bao, 1994, Neuroscience Letters.

Mixed Cocaine Agonist/Antagonist Properties of (+)-Methyl 4β-(4-Chlorophenyl)-1-methylpiperidine-3α-carboxylate, a Piperidine-Based Analog of Cocaine

Kenneth M. Johnson, A. Kozikowski, O. Deschaux, 2003, Journal of Pharmacology and Experimental Therapeutics.

Cocaine and dopamine differentially protect [3H]mazindol binding sites from alkylation by N-ethylmaleimide.

A. Kozikowski, J. S. Bergmann, K. Johnson, 1992, European journal of pharmacology.

Lithium Protection of Phencyclidine-Induced Neurotoxicity in Developing Brain: The Role of Phosphatidylinositol-3 Kinase/Akt and Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways

Kenneth M. Johnson, Yan Xia, N. Anastasio, 2008, Journal of Pharmacology and Experimental Therapeutics.

Pharmacological challenge reveals long-term effects of perinatal phencyclidine on delayed spatial alternation in rats

Kenneth M. Johnson, J. Wiley, K. L. Lavecchia, 2003, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Lithium Protection of Phencyclidine-induced Neurotoxicity in Developing Brain : the Role of PI-3 K / Akt and MEK / ERK Signaling Pathways

Kenneth M. Johnson, Yan Xia, N. Anastasio, 2008 .

An endogenous ligand of the brain σ/PCP receptor antagonizes NMDA-induced neurotransmitter release

Kenneth M. Johnson, L. Snell, R. Zukin, 1987, Brain Research.

Neurotoxic effects of MDMA (“ecstasy”) administration to neonatal rats

Kenneth M. Johnson, Syed F. Ali, J. Meyer, 2004, International Journal of Developmental Neuroscience.

Atypical anti-schizophrenic drugs prevent changes in cortical N-methyl-d-aspartate receptors and behavior following sub-chronic phencyclidine administration in developing rat pups

N. Anastasio, K. Johnson, 2008, Pharmacology Biochemistry and Behavior.

(R,S)‐α‐Amino‐3‐Hydroxy‐5‐Methylisoxazole‐4‐Propionic Acid (AMPA) Receptors Mediate a Calcium‐Dependent Inhibition of the Metabotropic Glutamate Receptor‐Stimulated Formation of Inositol 1,4,5‐Trisphosphate

Kenneth M. Johnson, G. Lonart, S. Alagarsamy, 1993 .

Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors.

Kenneth M. Johnson, A. Kozikowski, Jia Zhou, 2003, Bioorganic & medicinal chemistry letters.

Effects of amygdaloid kindling on NMDA receptor function and regulation

Kenneth M. Johnson, Susan M. Jones, K. Johnson, 1989, Experimental Neurology.

Comparisons between phencyclidine, its monohydroxylated metabolites, and the stereoisomers of N‐allyl‐N‐normetazocine (SKF 10047) as inhibitors of the muscarinic receptor and acetylcholinesterase

Kenneth M. Johnson, G. Hillman, K. Johnson, 1982, The Journal of pharmacy and pharmacology.

Mechanism of Action of rab3A in Mossy Fiber LTP

Kenneth M. Johnson, T. Südhof, R. Janz, 1998, Neuron.

Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.

Kenneth M. Johnson, A. Kozikowski, Kelly M. Giberson, 2005, Journal of medicinal chemistry.

Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants.

Kenneth M. Johnson, A. Kozikowski, Jia Zhou, 2005, Bioorganic & medicinal chemistry letters.

Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.

Kenneth M. Johnson, A. Kozikowski, Jia Zhou, 2004, Journal of medicinal chemistry.

Synthesis and Pharmacological Evaluation of (Z)‐9‐(Heteroarylmethylene)‐7‐azatricyclo[4.3.1.03,7]decanes: Thiophene Analogues as Potent Norepinephrine Transporter Inhibitors.

A. Kozikowski, Jia Zhou, Ao Zhang, 2004 .

Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.

Kenneth M. Johnson, A. Kozikowski, Jia Zhou, 2003, Journal of medicinal chemistry.

Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.

A. Kozikowski, A. Hoepping, Ao Zhang, 2002, Journal of medicinal chemistry.

Thiophene derivatives: a new series of potent norepinephrine and serotonin reuptake inhibitors.

Kenneth M. Johnson, S. Rong, A. Kozikowski, 2002, Bioorganic & medicinal chemistry letters.

TUNING THE SELECTIVITY OF MONOAMINE TRANSPORTER INHIBITORS BY THE STEREOCHEMISTRY OF THE NITROGEN LONE PAIR

Kenneth M. Johnson, J. Flippen-Anderson, A. Kozikowski, 1998 .

Erratum: Dopaminergic agents for the treatment of cocaine abuse (Drug Discovery Today (1999) issue 7, (322-332))

Kenneth M. Johnson, A. Kozikowski, A. Hoepping, 1999 .

Novel monoamine transporter ligands reduce cocaine-induced enhancement of brain stimulation reward

Kenneth M. Johnson, J. Stellar, S. Choi, 2001, Pharmacology Biochemistry and Behavior.

An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-(p-fluorophenyl)-2-propyltropanes.

A. Kozikowski, K. Johnson, K. Prakash, 2000, Bioorganic & medicinal chemistry letters.

Inhibition of N-methyl-d-aspartate-induced hippocampal [3H]norepinephrine release by phencyclidine is dependent on potassium concentration

L. Snell, Susan M. Jones, K. Johnson, 1987, Neuroscience Letters.

2,3-disubstituted 6-azabicyclo[3.2.1]octanes as novel dopamine transporter inhibitors.

Kenneth M. Johnson, A. Kozikowski, J. Bonjoch, 2004, Bioorganic & medicinal chemistry.