Bimal N. Desai

发表

Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.

Michael R. Elliott, D. Bayliss, K. Tung, 2021, Immunity.

Editorial: TRP Channels in Inflammation and Immunity

A. Schwab, S. Zierler, B. Desai, 2021, Frontiers in Immunology.

Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.

D. Clapham, G. Krapivinsky, L. Krapivinsky, 2012, Developmental cell.

Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

B. Kundu, R. Polanowska-Grabowska, N. Leitinger, 2020, Molecular metabolism.

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging

Sarah E. Ewald, Pankaj Kumar, Philip V Seegren, 2023, Nature Aging.

Revisiting multimodal activation and channel properties of Pannexin 1

D. Bayliss, Y. Chiu, Bayliss, 2018, The Journal of general physiology.

ATR Is Not Required for p53 Activation but Synergizes with p53 in the Replication Checkpoint*

S. Schreiber, P. Nghiem, P. K. Park, 2002, The Journal of Biological Chemistry.

Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

D. Clapham, M. Lipinski, Junying Yuan, 2014, Cell reports.

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

N. Leitinger, B. Desai, Vlad Serbulea, 2018, Proceedings of the National Academy of Sciences.

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein.

S. Schreiber, J. Hardwick, R. Peterson, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone

D. Bayliss, K. Ravichandran, N. Leitinger, 2017, Circulation research.

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

K. Hoehn, N. Leitinger, T. Harris, 2022, Science advances.

Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide‐Induced Toll‐Like Receptor 4 Endocytosis and Macrophage Activation

N. Leitinger, B. Desai, Samantha E. Adamson, 2018, Immunity.

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

Benjamin R. Myers, S. Schreiber, B. Desai, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg2+ Homeostasis

A. Donovan, D. Clapham, N. Andrews, 2008, Science.

Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity

B. Desai, Suresh K. Mendu, Michael S. Schappe, 2022, Nature Communications.

Deacetylation as a receptor-regulated direct activation switch for pannexin channels

D. Bayliss, T. Conrads, Hongyang Gao, 2021, Nature Communications.

Hematopoietic pannexin 1 function is critical for neuropathic pain

D. Bayliss, K. Ravichandran, S. Arandjelovic, 2017, Scientific Reports.

A high-conductance chemo-optogenetic system based on the vertebrate channel Trpa1b

Robert W. Mills, R. Peterson, D. Milan, 2017, Scientific Reports.

PANNEXIN 1 CHANNELS IN RENIN-EXPRESSING CELLS INFLUENCE RENIN SECRETION AND BLOOD PRESSURE HOMEOSTASIS.

D. Bayliss, P. Barrett, K. Ravichandran, 2020, Kidney international.

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

C. Boutell, Jon B. Suzich, Parijat Kundu, 2020, eLife.

Neuronal hyperexcitability is a DLK-dependent trigger of HSV-1 reactivation that can be induced by IL-1

C. Boutell, Jon B. Suzich, Parijat Kundu, 2020, bioRxiv.

TRP channels and mice deficient in TRP channels

D. Clapham, B. Desai, Bimal N. Desai, 2005, Pflügers Archiv.

Purinergic and Calcium Signaling in Macrophage Function and Plasticity

N. Leitinger, B. Desai, Bimal N. Desai, 2014, Front. Immunol..

Targeting ion channel TRPM7 promotes thymic development of Regulatory T cells by increasing IL-2-dependent STAT5 activation

E. Moser, T. Braciale, B. Desai, 2018, bioRxiv.

Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo

K. Lynch, Tao Huang, C. Doyle, 2023, bioRxiv.

TRPM7 regulates phagocytosis and clearance of Candida albicans

Eric J. Stipes, Philip V Seegren, M. Stremska, 2023, bioRxiv.

Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling

E. Moser, T. Braciale, Justin S. A. Perry, 2020, Science Signaling.

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

A. Kenworthy, N. Leitinger, L. Tamm, 2020, eLife.

Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

A. Periasamy, N. Leitinger, B. Desai, 2020, Cell reports.