Keith Davidson

发表

PI3Kβ Plays a Critical Role in Neutrophil Activation by Immune Complexes

K. Okkenhaug, H. Guillou, A. Mócsai, 2011, Science Signaling.

FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments.

P. Lipp, M. Bootman, P. Hawkins, 2001, Journal of cell science.

PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation

P. Hawkins, L. Stephens, K. Anderson, 2006, The EMBO journal.

Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils

Phillip T. Hawkins, Hervé Guillou, Martin Turner, 2006, Nature Cell Biology.

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils.

Hervé Guillou, Martin Turner, H. Guillou, 2006, Nature cell biology.

PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils.

P. Hawkins, L. Stephens, S. Walker, 2010, Blood.

Neutrophils from p40phox−/− mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing

P. Hawkins, L. Stephens, C. Ellson, 2006, The Journal of experimental medicine.

Signalling through Class I PI3Ks in mammalian cells.

P. Hawkins, L. Stephens, K. Anderson, 2006, Biochemical Society transactions.

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.

P. Hawkins, L. Stephens, O. Rausch, 2008, Blood.

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils.

K. Okkenhaug, M. Turner, P. Hawkins, 2005, Blood.

Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.

P. Lipp, P. Hawkins, L. Stephens, 2002, Molecular cell.

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of E.coli or S.aureus is regulated by Class III but not Class I or II PI3Ks

P. Hawkins, L. Stephens, O. Rausch, 2008 .

CD 18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI 3 Ks

P. Hawkins, L. Stephens, O. Rausch, 2008 .

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

Paul Tempst, Matthew A. Cooper, Piers R. J. Gaffney, 2001, Nature Cell Biology.

GPCR activation of Ras and PI3Kγ in neutrophils depends on PLCβ2/β3 and the RasGEF RasGRP4

H. Guillou, P. Hawkins, L. Stephens, 2012, The EMBO journal.

GPCR activation of Ras and PI 3 K c in neutrophils depends on PLC b 2 / b 3 and the RasGEF RasGRP

H. Guillou, P. Hawkins, L. Stephens, 2013 .

p84, a New Gβγ-Activated Regulatory Subunit of the Type IB Phosphoinositide 3-Kinase p110γ

P. Hawkins, L. Stephens, S. Suire, 2005, Current Biology.

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.

P. Hawkins, L. Stephens, S. Suire, 2005, Current biology : CB.

Frontline Science: TNF‐α and GM‐CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K‐γ, and neutrophil proinflammatory responses

P. Hawkins, L. Stephens, E. Santos, 2019, Journal of leukocyte biology.

The role of PI3Ks in the regulation of the neutrophil NADPH oxidase.

P. Hawkins, L. Stephens, Keith Davidson, 2007, Biochemical Society symposium.