Hiroshi Takano

DNA topoisomerase-targeting antitumor agents and drug resistance.

H. Takano, K. Kohno, M. Kuwano, 1992, Anti-cancer drugs.

Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells.

H. Takano, K. Kohno, M. Kuwano, 1991, Cancer research.

Reduction of drug accumulation and DNA topoisomerase II activity in acquired teniposide-resistant human cancer KB cell lines.

H. Takano, K. Kohno, M. Kuwano, 1990, Cancer research.

The direct activation of human multidrug resistance gene (MDR1) by anticancer agents.

H. Takano, K. Kohno, M. Kuwano, 1989, Biochemical and biophysical research communications.

Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression

H. Takano, H. Izumi, K. Kohno, 2000, Oncogene.

Cellular adaptation to drug exposure: evolution of the drug-resistant phenotype.

T. Fojo, H. Takano, Y. Matsumoto, 1997, Cancer research.