P. Faulder

Coumarin-based inhibitors of human NAD(P)H:quinone oxidoreductase-1. Identification, structure-activity, off-target effects and in vitro human pancreatic cancer toxicity.

D. Timson, I. Stratford, D. Ross, 2007, Journal of medicinal chemistry.

Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation.

Malcolm Anderson, Jason G Kettle, Alexander L Breeze, 2015, Journal of medicinal chemistry.

Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures.

O. Plotnikova, Zhulun Wang, Jinsong Liu, 2013, Bioorganic & medicinal chemistry letters.

Direct dynamics calculations of reaction rate and kinetic isotope effects in enzyme catalysed reactions.

G. Tresadern, N. Burton, I. H. Hillier, 2003, Faraday discussions.

From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome.

B. Bax, Joelle Le, Yoshiaki Washio, 2017, ACS medicinal chemistry letters.

Extreme tunnelling in methylamine dehydrogenase revealed by hybrid QM/MM calculations: potential energy surface profile for methylamine and ethanolamine substrates and kinetic isotope effect values

Gary Tresadern, Neil A. Burton, G. Tresadern, 2003 .

4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacy.

P. Bamborough, W. Rumsey, C. Chung, 2012, Bioorganic & medicinal chemistry letters.

QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase.

Kamaldeep K. Chohan, Nigel S. Scrutton, Gary Tresadern, 2001, Journal of the American Chemical Society.

Identification and optimization of a novel series of selective PIP5K inhibitors.

D. M. Andrews, N. Divecha, R. Rowlinson, 2021, Bioorganic & medicinal chemistry.