Vandna Munshi

发表

Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses.

G. McGaughey, Youwei Yan, M. Lai, 2008, Journal of medicinal chemistry.

Purification of untagged HIV-1 reverse transcriptase by affinity chromatography.

D. Hazuda, M. Lai, Y. Mei, 2010, Protein expression and purification.

Design and synthesis of pyridone inhibitors of non-nucleoside reverse transcriptase.

G. McGaughey, Youwei Yan, M. Lai, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.

G. McGaughey, Youwei Yan, M. Lai, 2011, Journal of medicinal chemistry.

Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs).

G. McGaughey, Youwei Yan, L. Gabryelski, 2008, Bioorganic & medicinal chemistry letters.

Inhibition of HIV-1 Ribonuclease H by a Novel Diketo Acid, 4-[5-(Benzoylamino)thien-2-yl]-2,4-dioxobutanoic Acid*

D. Hazuda, Michael D. Miller, J. Cole, 2003, The Journal of Biological Chemistry.

Mechanistic Study of Common Non-Nucleoside Reverse Transcriptase Inhibitor-Resistant Mutations with K103N and Y181C Substitutions

D. Hazuda, M. Lai, V. Munshi, 2016, Viruses.

Monitoring the development of non-nucleoside reverse transcriptase inhibitor-associated resistant HIV-1 using an electrochemiluminescence-based reverse transcriptase polymerase assay.

D. Hazuda, M. Lai, Michael D Miller, 2008, Analytical biochemistry.

Antiviral Activity of MK-4965, a Novel Nonnucleoside Reverse Transcriptase Inhibitor

D. Hazuda, Michael D. Miller, M. Lai, 2009, Antimicrobial Agents and Chemotherapy.

Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif.

Kenneth D Anderson, M. Lai, J. Vacca, 2010, Bioorganic & medicinal chemistry letters.

Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.

K. K. Nanda, D. Henze, M. Rudd, 2014, Journal of medicinal chemistry.

An in vitro Flaviviridae replicase system capable of authentic RNA replication.

J. Tomassini, L. Gan, R. Lafemina, 2003, Virology.

Design, synthesis, and X-ray crystallographic analysis of a novel class of HIV-1 protease inhibitors.

P. Orth, A. McPhail, Yong Zhang, 2011, Journal of medicinal chemistry.

Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.

M. Rowley, V. Summa, R. Laufer, 2006, Bioorganic & medicinal chemistry letters.