Jonathan G. Lees

发表

Gene3D: Extensive prediction of globular domains in proteins

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2017, Nucleic Acids Res..

A reference database for circular dichroism spectroscopy covering fold and secondary structure space

Andrew J. Miles, Jonathan G. Lees, Frank Wien, 2006, Bioinform..

cath-resolve-hits: a new tool that resolves domain matches suspiciously quickly

Ian Sillitoe, Tony E. Lewis, Jonathan G. Lees, 2018, Bioinform..

Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

Christine A. Orengo, Jonathan G. Lees, David T. Jones, 2017, PLoS Comput. Biol..

CATH: expanding the horizons of structure-based functional annotations for genome sequences

Ian Sillitoe, Janet M. Thornton, Christine A. Orengo, 2018, Nucleic Acids Res..

CATH: comprehensive structural and functional annotations for genome sequences

David A. Lee, Ian Sillitoe, Janet M. Thornton, 2014, Nucleic Acids Res..

Finding the “Dark Matter” in Human and Yeast Protein Network Prediction and Modelling

Christine A. Orengo, Jonathan G. Lees, Juan Garcia Ranea, 2010, PLoS Comput. Biol..

CATH FunFHMMer web server: protein functional annotations using functional family assignments

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2015, Nucleic Acids Res..

Functional classification of CATH superfamilies: a domain-based approach for protein function annotation

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2015, Bioinform..

Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data

Andrew J. Miles, Robert W. Janes, Jonathan G. Lees, 2006, BMC Bioinformatics.

The Gene3D Web Services: a platform for identifying, annotating and comparing structural domains in protein sequences

Phil Carter, Ian Sillitoe, Christine A. Orengo, 2011, Nucleic Acids Res..

CATH: an expanded resource to predict protein function through structure and sequence

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2016, Nucleic Acids Res..

Gene3D: comprehensive structural and functional annotation of genomes

Nigel J. Martin, Christine A. Orengo, Jonathan G. Lees, 2007, Nucleic Acids Res..

Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis

Ian Sillitoe, Christine A. Orengo, Jonathan G. Lees, 2011, Nucleic Acids Res..

Protein Structure Classification

Christine A. Orengo, Natalie L. Dawson, Jonathan G. Lees, 2019, Encyclopedia of Bioinformatics and Computational Biology.

Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2013, Nucleic Acids Res..

Functional classification of CATH superfamilies: a domain-based approach for protein function annotation

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2015, Bioinform..

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

David A. Lee, Ian Sillitoe, Janet M. Thornton, 2012, Nucleic Acids Res..

Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary structure determinations

Robert W. Janes, Jonathan G. Lees, 2007, BMC Bioinformatics.

FUN-L: gene prioritization for RNAi screens

Alfonso Valencia, Christine A. Orengo, Jonathan G. Lees, 2015, Bioinform..

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Tapio Salakoski, Feng Zhang, Paolo Fontana, 2019, Genome Biology.

Gene3D: expanding the utility of domain assignments

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2015, Nucleic Acids Res..

Gene3D: merging structure and function for a Thousand genomes

Christine A. Orengo, Jonathan G. Lees, Andrew B. Clegg, 2009, Nucleic Acids Res..

Gene3D: Extensive prediction of globular domains in proteins

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2017, Nucleic Acids Res..

Calibration and standardisation of synchrotron radiation and conventional circular dichroism spectrometers. Part 2: Factors affecting magnitude and wavelength

Andrew J. Miles, Jonathan G. Lees, Frank Wien, 2005 .

Calibration and Standardisation of Synchrotron Radiation Circular Dichroism and Conventional Circular Dichroism Spectrophotometers

Robert W. Janes, Jonathan G. Lees, Frank Wien, 2003 .

Functional classification of CATH superfamilies: a domain-based approach for protein function annotation

David A. Lee, Ian Sillitoe, Christine A. Orengo, 2015, Bioinform..

Identifying and characterising key alternative splicing events in Drosophila development

Christine A. Orengo, Jonathan G. Lees, C. Orengo, 2015, BMC Genomics.

Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery

Jonathan G. Lees, C. Orengo, J. Lees, 2017, Scientific Reports.

CATH: comprehensive structural and functional annotations for genome sequences

David A. Lee, Tony E. Lewis, Jonathan G. Lees, 2014, Nucleic Acids Res..

Functional classification of CATH superfamilies: a domain-based approach for protein function annotation

David A. Lee, Jonathan G. Lees, C. Orengo, 2015, Bioinform..

CDtool-an integrated software package for circular dichroism spectroscopic data processing, analysis, and archiving.

Jonathan G. Lees, Barry R. Smith, J G Lees, 2004, Analytical biochemistry.

CATH: increased structural coverage of functional space

Radka Svobodová Vareková, Su Datt Lam, Jonathan G. Lees, 2020, Nucleic Acids Res..

The evolution of protein functions and networks: a family-centric approach.

Jonathan G. Lees, Benoit H. Dessailly, Alison L. Cuff, 2009, Biochemical Society transactions.

Analyses of circular dichroism spectra of membrane proteins

Jonathan G. Lees, R. W. Janes, J. Lees, 2003, Protein science : a publication of the Protein Society.

Transient protein-protein interactions: structural, functional, and network properties.

Jonathan G. Lees, Benoit H. Dessailly, C. Orengo, 2010, Structure.

Protein Structure Classification

Jonathan G. Lees, C. Orengo, J. Lees, 2015, Encyclopedia of Bioinformatics and Computational Biology.

Tracing Evolution Through Protein Structures: Nature Captured in a Few Thousand Folds

Jonathan G. Lees, C. Orengo, J. Lees, 2021, Frontiers in Molecular Biosciences.

Broad functional profiling of fission yeast proteins using phenomics and machine learning

Jonathan G. Lees, Harry M. Scholes, Shaimaa A. Hassan, 2023, bioRxiv.

Systems biology approaches to finding novel pain mediators

Jonathan G. Lees, C. Orengo, J. Lees, 2013, Wiley interdisciplinary reviews. Systems biology and medicine.

PainNetworks: A web-based resource for the visualisation of pain-related genes in the context of their network associations

Jonathan G. Lees, Ilhem Diboun, Christine Orengo, 2013, PAIN®.

Uncovering the Molecular Machinery of the Human Spindle—An Integration of Wet and Dry Systems Biology

Alfonso Valencia, Søren Brunak, Jonathan G. Lees, 2012, PloS one.

Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury

Jonathan G. Lees, Christine Orengo, Stephen B. McMahon, 2018, Pain.

The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy

Jonathan G. Lees, Andreas C. Themistocleous, C. Orengo, 2016, Pain.

Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila

Jonathan G. Lees, Harry M. Scholes, C. Orengo, 2018, Scientific Reports.

Tracking dynamic changes in Alzheimer’s disease brain proteome reveals ageing-independent damage in Drosophila

Jonathan G. Lees, Harry M. Scholes, C. Orengo, 2018, bioRxiv.

Dynamic changes in the brain protein 1 interaction network correlates with 2 progression of Aβ42 pathology in 3 Drosophila 4

Jonathan G. Lees, Harry M. Scholes, C. Orengo, 2019 .

BIROn - Birkbeck Institutional Research Online

Jonathan G. Lees, F. Minneci, Kate McLoughlin, 2019 .

The Aquila Digital Community The Aquila Digital Community

Silvio C. E. Tosatto, Karin M. Verspoor, David A. Lee, 2022 .

SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals

Su Datt Lam, Jonathan G. Lees, Harry M. Scholes, 2020, Scientific Reports.

BIROn - Birkbeck Institutional Research Online reveal between

Jonathan G. Lees, C. Orengo, J. Lees, 2021 .

Biological impact of mutually exclusive exon switching

Su Datt Lam, Jonathan G. Lees, C. Orengo, 2021, PLoS Comput. Biol..

Systematic computational prediction of protein interaction networks

Jonathan G. Lees, C. Orengo, J. A. Ranea, 2011, Physical biology.

Structural and Functional View of Polypharmacology

John P. Overington, Jonathan G. Lees, Christine Orengo, 2016, bioRxiv.

An expanded evaluation of protein function prediction methods shows an improvement in accuracy

Tapio Salakoski, Paolo Fontana, Silvio C. E. Tosatto, 2016, Genome Biology.

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation

Alfonso Valencia, Jonathan G. Lees, Martin Krallinger, 2014, Molecular biology of the cell.