A. C. Pippione

发表

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK.

M. Kubbutat, J. Contreras, S. Al-Karadaghi, 2018, MedChemComm.

A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats

J. Kaplanski, C. Cifani, D. Boschi, 2021, Brain sciences.

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety

P. Circosta, B. Rolando, S. Al-Karadaghi, 2021, Journal of medicinal chemistry.

Dihydroorotate dehydrogenase inhibitors in anti-infective drug research.

D. Boschi, M. Lolli, A. Pippione, 2019, European journal of medicinal chemistry.

Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.

C. Andrade, B. Rolando, S. Al-Karadaghi, 2019, European journal of medicinal chemistry.

Hydroxyazoles as acid isosteres and their drug design applications—Part 1: Monocyclic systems

D. Boschi, M. Lolli, A. Pippione, 2021, Advances in Heterocyclic Chemistry.

Hydroxyazoles as acid isosteres and their drug design applications—Part 2: Bicyclic systems

D. Boschi, M. Lolli, A. Pippione, 2021, Advances in Heterocyclic Chemistry.

4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade.

M. Kubbutat, J. Contreras, S. Al-Karadaghi, 2017, MedChemComm.

Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.

C. Andrade, M. Piccinini, R. Friemann, 2017, European journal of medicinal chemistry.

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety

P. Circosta, B. Rolando, S. Al-Karadaghi, 2022, Journal of medicinal chemistry.

Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid.

W. Y. Wahlgren, Elisabetta Marini, S. Oliaro-Bosso, 2018, European journal of medicinal chemistry.

Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention

S. Oliaro-Bosso, D. Boschi, M. Lolli, 2017 .

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action

A. Rosato, P. Carloni, E. Baloglu, 2017, Nature Communications.

New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold.

F. Spyrakis, B. Rolando, D. Boschi, 2022, European journal of medicinal chemistry.

Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis

D. Boschi, M. Lolli, Tomasz M. Wróbel, 2023, Biomolecules.

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3.

W. Y. Wahlgren, Elisabetta Marini, B. Rolando, 2019, ACS medicinal chemistry letters.

Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach.

Elisabetta Marini, C. Cena, D. Boschi, 2017, European journal of medicinal chemistry.

The University of Bradford Institutional Repository

C. Cena, D. Boschi, Annalisa Costale, 2022 .

Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.

P. Circosta, B. Rolando, S. Al-Karadaghi, 2018, Journal of medicinal chemistry.

Dopaminergic therapies modulate the T‐CELL proteome of patients with Parkinson's disease

L. Lopiano, D. Cecconi, M. Zibetti, 2012, IUBMB life.

Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy.

F. Dosio, D. Boschi, M. Giorgis, 2018, Recent patents on anti-cancer drug discovery.

Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches

K. Janda, K. Martina, F. Dosio, 2015 .

Heterocyclic ring cleavage upon collision-induced dissociation of deprotonated 3-hydroxy-1,2,5-oxadiazoles (3-hydroxyfurazans).

Robert L. White, D. Boschi, M. Lolli, 2015, Journal of mass spectrometry : JMS.

The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia

P. Circosta, D. Cilloni, G. Saglio, 2020, bioRxiv.

Discovery and verification of panels of T-lymphocyte proteins as biomarkers of Parkinson's disease

Mauro Fasano, Tiziana Alberio, Leonardo Lopiano, 2012, Scientific Reports.

Parkinson's disease biomarkers in peripheral blood T lymphocytes: identification through a proteomic approach

A. Pippione, A. C. Pippione, 2013 .