B. L. Mylari

发表

Aldose reductase inhibitors: therapeutic implications for diabetic complications.

P. Oates, Oates, Mylari, 1999, Expert opinion on investigational drugs.

Design and synthesis of a novel family of triazine-based inhibitors of sorbitol dehydrogenase with oral activity: 1-[4-[3R,5S-dimethyl-4-(4-methyl-[1,3,5]triazin-2-yl)-piperazin-1-yl]-[1,3,5]triazin-2-yl]-(R) ethanol.

P. Oates, J. Coutcher, D. Beebe, 2003, Bioorganic & Medicinal Chemistry.

A sorbitol dehydrogenase inhibitor of exceptional in vivo potency with a long duration of action: 1-(R)-[4-[4-(4,6-dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl]ethanol.

P. Oates, J. Coutcher, M. O’Gorman, 2002, Journal of medicinal chemistry.

Orally-effective, long-acting sorbitol dehydrogenase inhibitors: synthesis, structure-activity relationships, and in vivo evaluations of novel heterocycle-substituted piperazino-pyrimidines.

M. Chu-Moyer, R. Berger, P. Oates, 2002, Journal of medicinal chemistry.

Sorbitol dehydrogenase inhibitors (SDIs): a new potent, enantiomeric SDI, 4-[2-1R-hydroxy-ethyl)-pyrimidin-4-yl]piperazine-1-sulfonic acid dimethylamide.

P. Oates, J. Coutcher, D. Beebe, 2001, Journal of medicinal chemistry.

Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners.

B. Mylari, E. R. Larson, T. A. Beyer, 1991, Journal of medicinal chemistry.

A novel series of non-carboxylic acid, non-hydantoin inhibitors of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and congeners.

P. Oates, J. Coutcher, M. O’Gorman, 2005, Journal of Medicinal Chemistry.

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

Paul D Adams, Ajith Kamath, V. L. Rath, 2003, Structure.

Anticoccidial derivatives of 6-azauracil. 2. High potency and long plasma life of N1-phenyl structures.

R. C. Koch, M. Miller, B. Mylari, 1979, Journal of medicinal chemistry.

Anticoccidial derivatives of 6-azauracil. 1. Enhancement of activity by benzylation of nitrogen-1. Observations on the design of nucleotide analogues in chemotherapy.

R. C. Koch, M. Miller, B. Mylari, 1977, Journal of medicinal chemistry.

Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation.

J. Nyengaard, C. Kilo, J. Williamson, 2010, Antioxidants & redox signaling.

Cyclopentanone synthesis by intramolecular carbon-hydrogen insertion of diazo ketones. A diterpene-to-steroid skeleton conversion

M. Curini, R. Pellicciari, B. Mylari, 1982 .

Lipophilic 1,3-xylyl-21-crown-6 macrocyclic polyether 2-carboxylic acids as biological mimics of the ionophore antibiotics.

A. Girard, F. J. Urban, L. Chappel, 1990, Journal of medicinal chemistry.

Pyridine-induced solvent shifts in the nuclear magnetic resonance spectra of hydroxylic compounds

D. Doddrell, B. Mylari, E. Wenkert, 1968 .

A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners.

B. Mylari, T. A. Beyer, T. W. Siegel, 1991, Journal of medicinal chemistry.