Chih-Rong Shyr

Chang-Yi Hsieh, Hsuan-Ying Huang, Chawnshang Chang, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Tumor-associated Macrophages Facilitate Bladder Cancer Progression by Increasing Cell Growth, Migration, Invasion and Cytokine Expression

C. Shyr, Chi-Ping Huang, Lianrui Liu, 2020, AntiCancer Research.

Differential Regulation of Direct Repeat 3 Vitamin D3and Direct Repeat 4 Thyroid Hormone Signaling Pathways by the Human TR4 Orphan Receptor*

Chawnshang Chang, Wen-Jye Lin, Yi-Fen Lee, 1999, The Journal of Biological Chemistry.

Combination of novel intravesical xenogeneic urothelial cell immunotherapy and chemotherapy enhances anti-tumor efficacy in preclinical murine bladder tumor models

C. Shyr, Chi-Ping Huang, Chun-Chie Wu, 2020, Cancer Immunology, Immunotherapy.

The anti-tumor effect of intravesical administration of normal urothelial cells on bladder cancer.

C. Shyr, Chi-Cheng Chen, Chi-Ping Huang, 2017, Cytotherapy.

Antiandrogen Therapy with Hydroxyflutamide or Androgen Receptor Degradation Enhancer ASC-J9 Enhances BCG Efficacy to Better Suppress Bladder Cancer Progression

E. Messing, S. Yeh, Chawnshang Chang, 2015, Molecular Cancer Therapeutics.

Increased Acetylation in the DNA-binding Domain of TR4 Nuclear Receptor by the Coregulator ARA55 Leads to Suppression of TR4 Transactivation*

J. Ni, Chawnshang Chang, Shaozhen Xie, 2011, The Journal of Biological Chemistry.

Androgen receptor expands the population of cancer stem cells in upper urinary tract urothelial cell carcinoma cells.

C. Shyr, Wen-Lin Chang, Chi-Cheng Chen, 2015, American journal of cancer research.

Intratumoral xenogeneic tissue-specific cell immunotherapy inhibits tumor growth by increasing antitumor immunity in murine triple negative breast and pancreatic tumor models.

C. Shyr, Chi-Ping Huang, Chun-Chie Wu, 2021, Cancer letters.

Anabolic androgens affect the competitive interactions in cell migration and adhesion between normal mouse urothelial cells and urothelial carcinoma cells.

Chawnshang Chang, C. Shyr, Chi-Cheng Chen, 2014, Biochemical and biophysical research communications.

Androgen receptor promotes the migration and invasion of upper urinary tract urothelial carcinoma cells through the upregulation of MMP-9 and COX-2.

Chawnshang Chang, Wen-Lung Ma, Caixia Zhang, 2013, Oncology reports.

Utilizing Xenogeneic Cells As a Therapeutic Agent for Treating Diseases

C. Shyr, Chi-Yu Yang, Chi-Ping Huang, 2021, Cell transplantation.

Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.

Xue-Ru Wu, Chawnshang Chang, H. Miyamoto, 2013, American Journal of Pathology.

Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts

Hong-Chiang Chang, S. Yeh, H. Moses, 2012, The Prostate.

Intravesical Administration of Xenogeneic Porcine Urothelial Cells Attenuates Cyclophosphamide-Induced Cystitis in Mice

C. Shyr, Chi-Cheng Chen, Chi-Ping Huang, 2019, Cell transplantation.

Xenogeneic cell therapy provides a novel potential therapeutic option for cancers by restoring tissue function, repairing cancer wound and reviving anti-tumor immune responses

C. Shyr, Chi-Cheng Chen, Chi-Ping Huang, 2018, Cancer Cell International.

Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.

Chawnshang Chang, Wei-Min Chuang, Wen-Lung Ma, 2013, Oncology reports.

Androgen Receptor Increases CD133 Expression and Progenitor-Like Population That Associate With Cisplatin Resistance in Endometrial Cancer Cell Line

Wei-Chun Chang, Y. Hung, Wen-Lung Ma, 2014, Reproductive Sciences.

Reduced osteoblast activity in the mice lacking TR4 nuclear receptor leads to osteoporosis

Chawnshang Chang, Gonghui Li, Yi-Fen Lee, 2012, Reproductive Biology and Endocrinology.

Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4.

H. Uno, C. Heinlein, Chawnshang Chang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Immunotherapeutic Agents for Intratumoral Immunotherapy

Chih-Rong Shyr, Lang-Chi Liu, Hui-Shan Chien, 2023, Vaccines.

Expression of androgen receptor co-regulators in the testes of men with azoospermia.

Yen-Ta Chen, C. Shyr, Ko-en Huang, 2008, Fertility and sterility.

Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling

E. Messing, S. Yeh, Chawnshang Chang, 2019, Oncogene.

Altered TNSALP Expression and Phosphate Regulation Contribute to Reduced Mineralization in Mice Lacking Androgen Receptor

Chawnshang Chang, Chiung-Kuei Huang, C. Shyr, 2008, Molecular and Cellular Biology.

Suppression of Estrogen Receptor-mediated Transcription and Cell Growth by Interaction with TR2 Orphan Receptor*

Chawnshang Chang, W. Che, Yueh-Chiang Hu, 2002, The Journal of Biological Chemistry.

Disruption of TR4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E/C-I/C-II Gene Cluster*

Chawnshang Chang, Shaozhen Xie, S. Yeh, 2003, Journal of Biological Chemistry.

Reduced prostate branching morphogenesis in stromal fibroblast, but not in epithelial, estrogen receptor α knockout mice.

Ming Chen, S. Yeh, Chiuan-Ren Yeh, 2012, Asian journal of andrology.

Targeting thymic epithelia AR enhances T-cell reconstitution and bone marrow transplant grafting efficacy.

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2013, Molecular endocrinology.

Tumor suppressor PAX6 functions as androgen receptor Co‐repressor to inhibit prostate cancer growth

S. Yeh, Chawnshang Chang, Chao-Cheng Huang, 2010, The Prostate.

Androgenic and antiandrogenic effects and expression of androgen receptor in mouse embryonic stem cells.

Chiung-Kuei Huang, C. Shyr, Ko-en Huang, 2006, Fertility and sterility.

Androgen receptor facilitates the recruitment of macrophages in tumor microenvironment to promote upper urinary tract urothelial cell carcinoma progression.

C. Shyr, Chi-Cheng Chen, Teng-Fu Hsieh, 2016, American journal of cancer research.

Targeted Inactivation of Testicular Nuclear Orphan Receptor 4 Delays and Disrupts Late Meiotic Prophase and Subsequent Meiotic Divisions of Spermatogenesis

Chawnshang Chang, Yi-Fen Lee, C. Shyr, 2004, Molecular and Cellular Biology.

Spermatogenesis and Testis Development Are Normal in Mice Lacking Testicular Orphan Nuclear Receptor 2

Chawnshang Chang, C. Shyr, K. Platt, 2002, Molecular and Cellular Biology.