Wim G. J. Hol

发表

Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes.

W G Hol, W. Hol, M. Allen, 1999, Proceedings of the National Academy of Sciences of the United States of America.

of three protozoan proteins from the isochorismatase superfamily Crystal structures and proposed structural / functional classification

K. Hodgson, P. Myler, E. Boni, 2005 .

Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum.

W G Hol, W. Hol, U. Certa, 1998, Biochemistry.

Structure-based drug design: progress, results and challenges.

C L Verlinde, W G Hol, C. Verlinde, 1994, Structure.

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex.

W. Hol, K. H. Kalk, G. Obmolova, 1993, Science.

Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site.

C L Verlinde, W G Hol, C. Verlinde, 1995, Biochemistry.

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

M. Gelb, F. Buckner, W. V. Voorhis, 2000, Journal of medicinal chemistry.

Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.

M. Gelb, C. Verlinde, W. Hol, 2001, Journal of molecular biology.

Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design.

C. Verlinde, Wim G. J. Hol, Michael H. Gelb, 1998, Journal of Medicinal Chemistry.

Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness

F. Buckner, C. Verlinde, W. Hol, 2014, PLoS neglected tropical diseases.

Selective Tight Binding Inhibitors of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase via Structure-Based Drug Design.

C. Verlinde, Wim G. J. Hol, Michael H. Gelb, 1999 .

Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.

F. Opperdoes, C. Verlinde, P. Herdewijn, 1994, Journal of medicinal chemistry.

A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.

Wim G J Hol, F. Buckner, C. Verlinde, 2015, Acta crystallographica. Section D, Biological crystallography.

Structure determination of the glycosomal triosephosphate isomerase from Trypanosoma brucei brucei at 2.4 A resolution.

K. H. Kalk, R. Wierenga, W. Hol, 1987, Journal of molecular biology.