Be’eri Niego

发表

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

David K. Wright, R. Medcalf, K. Wilson, 2019, Journal of thrombosis and haemostasis : JTH.

Molecular Imaging of Atrial Myopathy: Towards Early AF detection and Non-invasive Disease Management.

C. Hagemeyer, S. Lal, B. Niego, 2020, Trends in cardiovascular medicine.

Applications of Nanotechnology in the Diagnosis and Therapy of Stroke

D. Howells, C. Hagemeyer, B. Sutherland, 2019, Seminars in Thrombosis and Hemostasis.

Plasmin-Dependent Modulation of the Blood–Brain Barrier: A Major Consideration during tPA-Induced Thrombolysis?

R. Medcalf, B. Niego, Be’eri Niego, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Studies into the interaction between the plasminogen activating system and the blood-brain barrier

B. Niego, Be’eri Niego, 2013 .

Valproic acid selectively increases vascular endothelial tissue‐type plasminogen activator production and reduces thrombus formation in the mouse

R. Medcalf, S. Jern, S. Jackson, 2016, Journal of thrombosis and haemostasis : JTH.

Improved method for the preparation of a human cell-based, contact model of the blood-brain barrier.

Be'eri Niego, Robert L Medcalf, R. Medcalf, 2013, Journal of visualized experiments : JoVE.

Tissue‐type plasminogen activator requires a co‐receptor to enhance NMDA receptor function

David R. Croucher, D. Croucher, D. Lawrence, 2008, Journal of neurochemistry.

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

R. Medcalf, N. Lee, B. Niego, 2017, PloS one.

t-PA Suppresses the Immune Response and Aggravates Neurological Deficit in a Murine Model of Ischemic Stroke

R. Medcalf, B. Niego, D. Draxler, 2019, Front. Immunol..

A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury.

R. Medcalf, P. Crack, A. Samson, 2009, Blood.

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Hugo J Albers, C. Hagemeyer, A. D. van der Meer, 2020, Haematologica.

LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH

C. Sobey, R. Medcalf, B. Broughton, 2017, Fluids and Barriers of the CNS.

Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa

K. Peter, R. Medcalf, C. Hagemeyer, 2017, Journal of the American Heart Association.

Collagen‐Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis

C. Hagemeyer, B. Niego, P. Donnelly, 2021, Journal of the American Heart Association.

Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo

R. Medcalf, P. Daniel, A. Samson, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Shear-Dependent Platelet Aggregation: Mechanisms and Therapeutic Opportunities

C. Hagemeyer, B. Niego, E. Westein, 2019, Front. Cardiovasc. Med..

Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin

R. Medcalf, A. Samson, B. Niego, 2011, Brain Research.

Tissue-Type Plasminogen Activator and Tenecteplase-Mediated Increase in Blood Brain Barrier Permeability Involves Cell Intrinsic Complement

T. Woodruff, R. Medcalf, Z. McQuilten, 2020, Frontiers in Neurology.

Two conserved regions within the tissue‐type plasminogen activator gene promoter mediate regulation by brain‐derived neurotrophic factor

A. Tjärnlund-Wolf, R. Medcalf, P. Daniel, 2007, The FEBS journal.

Platelet-targeted thrombolysis for treatment of acute ischemic stroke

David K. Wright, R. Medcalf, C. Hagemeyer, 2022, Blood advances.

Assessment of the epi-pericardial fibrotic substrate by collagen-targeted probes

C. Hagemeyer, B. Niego, P. Donnelly, 2022, Scientific Reports.

Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers.

F. Caruso, Shuaijun Pan, Yi Ju, 2022, ACS applied materials & interfaces.

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions

David R. Croucher, L. Pedersen, R. Medcalf, 2014, Brain Research.

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.

R. Medcalf, A. Turnley, B. Niego, 2012, Blood.

Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo

R. Medcalf, P. Daniel, A. Samson, 2006, The FASEB Journal.

Molecular Imaging of Diffuse Cardiac Fibrosis with a Radiotracer That Targets Proteolyzed Collagen IV.

Asif Noor, Martin Ezeani, K. Alt, 2024, Radiology. Cardiothoracic imaging.

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid.

R. Medcalf, B. Niego, P. Coughlin, 2008, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

R. Medcalf, S. Petratos, F. Alderuccio, 2016, PloS one.

Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination

A. Harvey, S. Strittmatter, Y. Sekine, 2019, The Journal of Neuroscience.