Chie Unemura

发表

New Highly Selective BACE1 Inhibitors and Their Effects on Dendritic Spine Density In Vivo

J. Herms, S. Lichtenthaler, Naotaka Horiguchi, 2023, International journal of molecular sciences.

Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine β-Secretase (BACE1) Inhibitors via Active Conformation Stabilization.

Kenji Nakahara, Takahiko Yamamoto, K. Kusakabe, 2018, Journal of medicinal chemistry.

Rational Design of Novel 1,3-Oxazine Based β-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust Aβ Reduction in the Brain.

K. Kusakabe, Y. Kido, T. Fukushima, 2018, Journal of medicinal chemistry.

PRECLINICAL MULTI-SPECIES PHARMACOKINETIC/PHARMACODYNAMIC ANALYSIS OF THE ORAL BACE INHIBITOR JNJ-54861911

Y. Nakajima, G. Sakaguchi, H. Borghys, 2017, Alzheimer's & Dementia.