Dezerae Cox

发表

Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers

C. Dobson, D. Klenerman, M. Horrocks, 2018, Cell reports.

A biosensor-based framework to measure latent proteostasis capacity

M. Oliveberg, A. Dickson, S. Ebbinghaus, 2018, Nature Communications.

Characterization and super-resolution imaging of small tau aggregates in human samples

D. Klenerman, W. McEwan, J. S. Danial, 2023, bioRxiv.

Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer’s clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1

D. Cox, Boyin Liu, Matthew W. A. Dixon, 2022, PLoS pathogens.

Virulence determinant, PTP7, controls vesicle budding from the Maurer’s clefts, adhesin protein trafficking and host cell remodeling in Plasmodium falciparum

D. Cox, Boyin Liu, Matthew W. A. Dixon, 2021, bioRxiv.

The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity

Antoine M. van Oijen, C. Dobson, D. Klenerman, 2018, The Journal of Biological Chemistry.

Explorer Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic -Synuclein Oligomers

D. Klenerman, M. Horrocks, H. Ecroyd, 2018 .

Explorer Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic -Synuclein Oligomers

D. Klenerman, M. Horrocks, H. Ecroyd, 2018 .

The interaction of small heat shock molecular chaperone proteins with a-synuclein

D. Cox, Dezerae Cox, 2016 .

Protein aggregation in cell biology: An aggregomics perspective of health and disease.

D. Cox, D. Hatters, Xiaojing Sui, 2020, Seminars in cell & developmental biology.

The small heat shock proteins αB-crystallin (HSPB5) and Hsp27 (HSPB1) inhibit the intracellular aggregation of α-synuclein

D. Cox, H. Ecroyd, Dezerae Cox, 2017, Cell Stress and Chaperones.

Cellular aging impedes stress-activation of a crucial JDP-Hsp70 protein disaggregase

H. Kampinga, S. Arumugam, D. Cox, 2022 .

N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation

P. Gooley, D. Cox, H. Ecroyd, 2020, The Journal of Biological Chemistry.

A biosensor of protein foldedness identifies increased “holdase” activity of chaperones in the nucleus following increased cytosolic protein aggregation

A. Dickson, S. Ebbinghaus, Christian Makhoul, 2022, The Journal of biological chemistry.

A biosensor to gauge protein homeostasis resilience differences in the nucleus compared to cytosol of mammalian cells

A. Dickson, S. Ebbinghaus, G. McColl, 2021, bioRxiv.

PINK1 signalling in neurodegenerative disease

C. Sue, D. Cox, D. Whiten, 2021, Essays in biochemistry.

Sequence grammar underlying the unfolding and phase separation of globular proteins.

R. Pappu, S. Radford, D. Ascher, 2022, Molecular cell.

Widespread remodeling of proteome solubility in response to different protein homeostasis stresses

Douglas E. V. Pires, M. Vendruscolo, G. Reid, 2020, Proceedings of the National Academy of Sciences.

The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

Georg K. A. Hochberg, D. Eisenberg, J. Stroud, 2014, Proceedings of the National Academy of Sciences.

Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells

D. Cox, A. Walker, H. Ecroyd, 2020, Journal of Cell Science.

Preventing α-synuclein aggregation: the role of the small heat-shock molecular chaperone proteins.

J. Carver, D. Cox, H. Ecroyd, 2014, Biochimica et biophysica acta.

Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation*

H. Ecroyd, Emily E. Selig, Dezerae Cox, 2016, The Journal of Biological Chemistry.

Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli

D. Cox, D. Hatters, Angelique R. Ormsby, 2022, bioRxiv.

Hidden information on protein function in censuses of proteome foldedness

Nadinath B. Nillegoda, C. Ang, D. Cox, 2021, Nature Communications.