Cleo Kontoravdi

发表

Dynamic model of MAb production and glycosylation for the purpose of product quality control

Cleo Kontoravdi, Steven P. Asprey, Stratos Pistikopoulos, 2005 .

Applying quality by design to glycoprotein therapeutics: experimental and computational efforts of process control

Cleo Kontoravdi, Karen M. Polizzi, Philip M. Jedrzejewski, 2013 .

Systematic methodology for the development of mathematical models for biological processes.

Cleo Kontoravdi, C. Kontoravdi, 2013, Methods in molecular biology.

Development and design of bio-pharmaceutical processes

Nilay Shah, Cleo Kontoravdi, Nouri J. Samsatli, 2013 .

Constrained global sensitivity analysis for bioprocess design space identification

Nilay Shah, Cleo Kontoravdi, Oleksiy V. Klymenko, 2019, Comput. Chem. Eng..

The era of big data: Genome-scale modelling meets machine learning

Cleo Kontoravdi, Pavlos Kotidis, Athanasios Antonakoudis, 2020, Computational and structural biotechnology journal.

Low-cost and user-friendly biosensor to test the integrity of mRNA molecules suitable for field applications.

Cleo Kontoravdi, Karen M Polizzi, Ignacio Moya Ramírez, 2019, Biosensors & bioelectronics.

Computational tools for predicting and controlling the glycosylation of biopharmaceuticals

Cleo Kontoravdi, Ioscani Jimenez del Val, C. Kontoravdi, 2018, Current Opinion in Chemical Engineering.

Cell cycle modelling for off-line dynamic optimisation of mammalian cultures

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2008 .

An integrated modelling/experimental framework for protein-producing cell cultures

Cleo Kontoravdi, C. Kontoravdi, 2007 .

Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2007, Comput. Chem. Eng..

Systematic development of predictive mathematical models for animal cell cultures

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2010, Comput. Chem. Eng..

'Closing the loop' in biological systems modeling - From the in silico to the in vitro

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2011, Autom..

DigiGlyc: A hybrid tool for reactive scheduling in cell culture systems

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Maria M. Papathanasiou, 2021, Comput. Chem. Eng..

Synergising stoichiometric modelling with artificial neural networks to predict antibody glycosylation patterns in Chinese hamster ovary cells

Cleo Kontoravdi, Ioscani Jimenez del Val, Athanasios Antonakoudis, 2021, Comput. Chem. Eng..

Application of Global Sensitivity Analysis to Determine Goals for Design of Experiments: An Example Study on Antibody‐Producing Cell Cultures

Cleo Kontoravdi, Athanasios Mantalaris, S. P. Asprey, 2008, Biotechnology progress.

Whole‐cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production

Cleo Kontoravdi, Paul S. Freemont, Karen M. Polizzi, 2017, Biotechnology and bioengineering.

A multi‐pronged investigation into the effect of glucose starvation and culture duration on fed‐batch CHO cell culture

Cleo Kontoravdi, Christian Müller, M. Andersen, 2015, Biotechnology and bioengineering.

How does mild hypothermia affect monoclonal antibody glycosylation?

Cleo Kontoravdi, Sarantos Kyriakopoulos, Karen M. Polizzi, 2015, Biotechnology and bioengineering.

A framework for the systematic design of fed‐batch strategies in mammalian cell culture

Cleo Kontoravdi, Sarantos Kyriakopoulos, C. Kontoravdi, 2014, Biotechnology and bioengineering.

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation

Cleo Kontoravdi, Karen M. Polizzi, Ioscani Jimenez del Val, 2016, Scientific Reports.

Genome-based kinetic modeling of cytosolic glucose metabolism in industrially relevant cell lines: Saccharomyces cerevisiae and Chinese hamster ovary cells

Ning Chen, Cleo Kontoravdi, Karen M. Polizzi, 2012, Bioprocess and Biosystems Engineering.

Dynamic Optimization of Bioprocesses

Cleo Kontoravdi, George Koumpouras, 2012 .

An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells.

Cleo Kontoravdi, Sarantos Kyriakopoulos, Karen M Polizzi, 2013, Analytical biochemistry.

A model‐based quantification of the impact of new manufacturing technologies on developing country vaccine supply chain performance: A Kenyan case study

Nilay Shah, Cleo Kontoravdi, Maria Papathanasiou, 2019, Journal of Advanced Manufacturing and Processing.

Metabolic network reconstruction: advances in in silico interpretation of analytical information.

Ning Chen, Cleo Kontoravdi, Sarantos Kyriakopoulos, 2012, Current opinion in biotechnology.

Global sensitivity analysis and meta-modeling of an ethanol production process

Nilay Shah, Cleo Kontoravdi, David J. Leak, 2014 .

Model‐based investigation of intracellular processes determining antibody Fc‐glycosylation under mild hypothermia

Cleo Kontoravdi, Karen M Polizzi, Si Nga Sou, 2017, Biotechnology and bioengineering.