Athanasios Mantalaris

发表

Dynamic model of MAb production and glycosylation for the purpose of product quality control

Cleo Kontoravdi, Steven P. Asprey, Stratos Pistikopoulos, 2005 .

A control strategy for periodic systems – application to the twin-column MCSGP

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2015 .

Global Sensitivity Analysis for a Model of B-Cell Chronic Lymphocytic Leukemia Disease Trajectories

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Ruth Misener, 2015 .

Energy-based culture medium design for biomanufacturing optimization: A case study in monoclonal antibody production by GS-NS0 cells.

Athanasios Mantalaris, Ana L Quiroga-Campano, Nicki Panoskaltsis, 2018, Metabolic engineering.

Optimisation under uncertainty for a bioreactor that produces red blood cells

Athanasios Mantalaris, Ruth Misener, Eirini Velliou, 2014 .

Application of global sensitivity analysis to biological models

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Maria Rodriguez-Fernandez, 2008 .

Advanced control strategies for a periodic, two-column chromatographic process

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Maria M. Papathanasiou, 2016, 2016 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR).

Intelligent, model-based control towards the intensification of downstream processes

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Massimo Morbidelli, 2017, Comput. Chem. Eng..

Cyclin and DNA Distributed Cell Cycle Model for GS-NS0 Cells

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2015, PLoS Comput. Biol..

Research review paper Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments

Emmanuel M. Drakakis, Athanasios Mantalaris, Hua Ye, 2007 .

Intelligent bioprocessing for haemotopoietic cell cultures using monitoring and design of experiments.

Athanasios Mantalaris, Hua Ye, Xicai Yue, 2007, Biotechnology advances.

Model Development and Analysis of Mammalian Cell Culture Systems

Efstratios N. Pistikopoulos, Efstratios N. Pistikopoulos, Athanasios Mantalaris, 2011 .

A Personalized Framework for Dynamic Modeling of Disease Trajectories in Chronic Lymphocytic Leukemia

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Ruth Misener, 2016, IEEE Transactions on Biomedical Engineering.

A comprehensive mathematical analysis of a novel multistage population balance model for cell proliferation

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2016, Comput. Chem. Eng..

Tissue engineering : a passing fad or a viable field for chemical engineers ?

Athanasios Mantalaris, 2001 .

A centralized/decentralized control approach for periodic systems with application to chromatographic separation processes

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2016 .

Stem cell bioprocessing: fundamentals and principles

Mayasari Lim, Athanasios Mantalaris, Yunyi Kang, 2009, Journal of The Royal Society Interface.

Green hierarchical composites: The bottom-up approach

Athanasios Mantalaris, Alexander Bismarck, Ky Lee, 2009 .

A framework for the design, modeling and optimization of biomedical systems

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Ruth Misener, 2014 .

Design of optimal patient-specific chemotherapy protocols for the treatment of acute myeloid leukemia (AML)

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2013, Comput. Chem. Eng..

In Silico Closed-Loop Control Validation Studies for Optimal Insulin Delivery in Type 1 Diabetes

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2015, IEEE Transactions on Biomedical Engineering.

Advanced Computational Tools To Enhance Continuous Monoclonal Antibody Production

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Maria M. Papathanasiou, 2015 .

Dynamic Optimization of the Production of Monoclonal Antibodies in Semi-batch Operation

Alexander Mitsos, Adel Mhamdi, Athanasios Mantalaris, 2017 .

A Real-Time Multi-Channel Monitoring System for Stem Cell Culture Process

Emmanuel M. Drakakis, Athanasios Mantalaris, Hua Ye, 2008, IEEE Transactions on Biomedical Circuits and Systems.

A Two-Phase Transport Model for the Human Bone Marrow

Athanasios Mantalaris, Robin Kumar, Frantisek Stepanek, 2004 .

Generation of spatio-temporal concentration profiles for cell culture systems: A case study in ammonia

Emmanuel M. Drakakis, Athanasios Mantalaris, Xicai Yue, 2010 .

Development of advanced computational tools for the intensification of monoclonal antibody production

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2016 .

Modeling and Analysis of Individualized Pharmacokinetics and Pharmacodynamics for Volatile Anesthesia

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2014, IEEE Transactions on Biomedical Engineering.

Chemotherapy Drug Scheduling for the Induction Treatment of Patients With Acute Myeloid Leukemia

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2014, IEEE Transactions on Biomedical Engineering.

Cell cycle modelling for off-line dynamic optimisation of mammalian cultures

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2008 .

A centralized/decentralized control approach for the Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) process

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Massimo Morbidelli, 2015 .

Product and Process Design: Toward Industrial TE Manufacturing

Liesbet Geris, Athanasios Mantalaris, Jean-Marie Aerts, 2014 .

Model-Based Dynamic Optimization of Monoclonal Antibodies Production in Semibatch Operation—Use of Reformulation Techniques

Alexander Mitsos, Adel Mhamdi, Athanasios Mantalaris, 2018 .

Development of a Design of Experiment Methodology: Applications to the Design and Analysis of Experiments

Athanasios Mantalaris, Mayasari Lim, 2008 .

Bioprocess systems engineering: transferring traditional process engineering principles to industrial biotechnology

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Alexandros Kiparissides, 2012, Computational and structural biotechnology journal.

A systematic framework for the design, simulation and optimization of personalized healthcare: Making and healing blood

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Ruth Misener, 2015, Comput. Chem. Eng..

Stem cell biomanufacturing under uncertainty: A case study in optimizing red blood cell production

Mark C Allenby, Athanasios Mantalaris, Ruth Misener, 2017, AIChE journal. American Institute of Chemical Engineers.

A Quantitative Three-Dimensional Image Analysis Tool for Maximal Acquisition of Spatial Heterogeneity Data.

Mark C Allenby, Athanasios Mantalaris, Ruth Misener, 2017, Tissue engineering. Part C, Methods.

Towards information-rich bioprocessing: Generation of spatio-temporal profiles through the use of design of experiments to determine optimal number and location of sensors—An example in thermal profiles

Emmanuel M. Drakakis, Athanasios Mantalaris, Xicai Yue, 2008 .

Free Energy Predictions of Ligand Binding to an α-Helix Using Steered Molecular Dynamics and Umbrella Sampling Simulations

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Yanyan Zhao, 2014, J. Chem. Inf. Model..

An On-line, Multi-Parametric, Multi-Channel Physicochemical Monitoring Platform for Stem Cell Culture Bioprocessing

Christofer Toumazou, Emmanuel M. Drakakis, Athanasios Mantalaris, 2007, 2007 IEEE International Symposium on Circuits and Systems.

Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2007, Comput. Chem. Eng..

A predictive mathematical model of cell cycle, metabolism and apoptosis of monoclonal antibody-producing GS-NS0 cells.

Athanasios Mantalaris, António L Grilo, A. Mantalaris, 2019, Biotechnology journal.

Sequential and Simultaneous Optimization Strategies for Increased Production of Monoclonal Antibodies

Alexander Mitsos, Adel Mhamdi, Athanasios Mantalaris, 2019, Computer Aided Chemical Engineering.

Systematic development of predictive mathematical models for animal cell cultures

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2010, Comput. Chem. Eng..

On the model based optimization of secreting mammalian cell cultures via minimal glucose provision

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Alexandros Kiparissides, 2011 .

Advanced control strategies for the multicolumn countercurrent solvent gradient purification process

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2016 .

A dual-parameter identification approach for data-based predictive modeling of hybrid gene regulatory network-growth kinetics in Pseudomonas putida mt-2

Julio R. Banga, Athanasios Mantalaris, Jake Alan Pitt, 2020, Bioprocess and Biosystems Engineering.

A CFD-based computer aided design of an automated large-scale cardiogenic 3D bioprocess of encapsulated embryionic stem cells

Alberto Redaelli, Athanasios Mantalaris, Diego Gallo, 2010 .

Optimization of CAR T-cell therapies supply chains

Athanasios Mantalaris, Michael C. Georgiadis, Nicki Panoskaltsis, 2020, Comput. Chem. Eng..

Development of advanced control strategies for periodic systems: An application to chromatographic separation processes

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2016, 2016 American Control Conference (ACC).

Computational tools for the advanced control of periodic processes - Application to a chromatographic separation

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Richard Oberdieck, 2016 .

'Closing the loop' in biological systems modeling - From the in silico to the in vitro

Efstratios N. Pistikopoulos, Cleo Kontoravdi, Athanasios Mantalaris, 2011, Autom..

Robust Superstructure Optimisation of a Bioreactor that Produces Red Blood Cells

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Jonathan Chin, 2014 .

Global superstructure optimisation of red blood cell production in a parallelised hollow fibre bioreactor

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Ruth Misener, 2014, Comput. Chem. Eng..

Patient‐Specific 3D Bioprinted Models of Developing Human Heart

Athanasios Mantalaris, Bowen Jing, John N Oshinski, 2020, Advanced healthcare materials.

Proliferation rates of HepG2 cells encapsulated in alginate are increased in a microgravity environment compared with static cultures.

Athanasios Mantalaris, Clare Selden, A. Mantalaris, 2005, Artificial organs.

Optimization of Insulin Dosing in Patients with Type 1 Diabetes Mellitus

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2014 .

An unstructured model of metabolic and temperature dependent cell cycle arrest in hybridoma batch and fed-batch cultures

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Massimo Morbidelli, 2015 .

A coupled single cell-population-balance model for mammalian cell cultures

Steven P. Asprey, Athanasios Mantalaris, S. P. Asprey, 2006 .

Coupled oxygen–carbon dioxide transport model for the human bone marrow

Athanasios Mantalaris, Nicki Panoskaltsis, Frantisek Stepanek, 2008 .

Application of Global Sensitivity Analysis to Determine Goals for Design of Experiments: An Example Study on Antibody‐Producing Cell Cultures

Cleo Kontoravdi, Athanasios Mantalaris, S. P. Asprey, 2008, Biotechnology progress.

Linking genes to microbial growth kinetics: an integrated biochemical systems engineering approach.

Athanasios Mantalaris, Victor de Lorenzo, Alexandros Kiparissides, 2011, Metabolic engineering.

Spatiotemporal Mapping of Erythroid, Stromal, and Osteogenic Niche Formation to Support Physiologic Red Cell Production in a Three-Dimensional Hollow Fibre Perfusion Bioreactor

Athanasios Mantalaris, Ruth Misener, Nicki Panoskaltsis, 2016 .

The impact of succinate trace on pWW0 and ortho-cleavage pathway transcription in Pseudomonas putida mt-2 during toluene biodegradation.

Athanasios Mantalaris, Michalis Koutinas, A. Tsipa, 2017, Bioresource technology.

More than meets the eye in bacterial cellulose: biosynthesis, bioprocessing, and applications in advanced fiber composites.

Athanasios Mantalaris, Alexander Bismarck, Koon-Yang Lee, 2014, Macromolecular bioscience.

POLYHYDROXYALKANOATES (PHAs) FOR TISSUE ENGINEERING APPLICATIONS: BIOTRANSFORMATION OF PALM OIL MILL EFFLUENT (POME) TO VALUE-ADDED POLYMERS

Athanasios Mantalaris, Alexander Bismarck, A. Mantalaris, 2015 .

Computational approach for understanding and improving GS-NS0 antibody production under hyperosmotic conditions.

Athanasios Mantalaris, Alexandros Kiparissides, Efstratios N Pistikopoulos, 2012, Journal of bioscience and bioengineering.

The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance.

Athanasios Mantalaris, Julia M Polak, J. Polak, 2008, Biomaterials.

Modelling of the Insulin Delivery System for patients with Type 1 Diabetes Mellitus

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2011 .

Ex vivo mimicry of normal and abnormal human hematopoiesis.

Athanasios Mantalaris, Maria Rende, Nicki Panoskaltsis, 2012, Journal of visualized experiments : JoVE.

Production of human osteoclasts in a three-dimensional bone marrow culture system

Athanasios Mantalaris, P. Bourne, A. Mantalaris, 2004 .

A combined fluid dynamics, mass transport and cell growth model for a three-dimensional perfused biorector for tissue engineering of haematopoietic cells

Athanasios Mantalaris, Xiao Yun Xu, A. Mantalaris, 2007 .

Advanced model‐based control strategies for the intensification of upstream and downstream processing in mAb production

Athanasios Mantalaris, Fabian Steinebach, Ana L Quiroga-Campano, 2017, Biotechnology progress.

A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2015, Journal of The Royal Society Interface.

Global Sensitivity Analysis Challenges in Biological Systems Modeling

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Alexandros Kiparissides, 2009 .

Optimal bioprocess design through a gene regulatory network - Growth kinetic hybrid model: Towards replacing Monod kinetics.

Athanasios Mantalaris, Michalis Koutinas, A. Tsipa, 2018, Metabolic engineering.

The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia.

Athanasios Mantalaris, Nicki Panoskaltsis, Alexander Bismarck, 2010, Biomaterials.

Improving Embryonic Stem Cell Expansion through the Combination of Perfusion and Bioprocess Model Design

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Alexandros Kiparissides, 2013, PloS one.

Selecting a Differential Equation Cell Cycle Model for Simulating Leukemia Treatment

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2015 .

Global Parametric Identifiability of a Dynamic Unstructured Model of Hybridoma Cell Culture

Steven P. Asprey, Athanasios Mantalaris, 2001 .

Nondestructive technique for the characterization of the pore size distribution of soft porous constructs for tissue engineering.

Athanasios Mantalaris, Laleh Safinia, Alexander Bismarck, 2006, Langmuir : the ACS journal of surfaces and colloids.

Influence of culture pH on proliferation and cardiac differentiation of murine embryonic stem cells

Mayasari Lim, Athanasios Mantalaris, Ailing Teo, 2014 .

Transcriptional kinetics of the cross-talk between the ortho-cleavage and TOL pathways of toluene biodegradation in Pseudomonas putida mt-2.

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Michalis Koutinas, 2016, Journal of biotechnology.

A Coupled Single Cell-Population Balance Model for Mammalian Cell Cultures

Steven P. Asprey, Athanasios Mantalaris, Fabio R. Sidoli, 2004 .

A Novel Physiologically Based Compartmental Model for Volatile Anaesthesia

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2011 .

Metabolomics Analysis of the Osteogenic Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells Reveals Differential Sensitivity to Osteogenic Agents

Athanasios Mantalaris, Spyros I. Vernardis, Eleftherios Tsiridis, 2017, Stem cells and development.

A study on Fe(2+) - α-helical-rich keratin complex formation using isothermal titration calorimetry and molecular dynamics simulation.

Athanasios Mantalaris, Lujia Han, Jan K Marzinek, 2014, Journal of pharmaceutical sciences.

Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds.

Athanasios Mantalaris, Nicki Panoskaltsis, Alexander Bismarck, 2011, Biomaterials.

An Oxygen Transport Model for Human Bone Marrow Microcirculation

Athanasios Mantalaris, Frantisek Stepanek, F. Štěpánek, 2004 .

Towards a high-fidelity model for model based optimisation of drug delivery systems in acute myeloid leukemia

Michael C. Georgiadis, Athanasios Mantalaris, Nicki Panoskaltsis, 2011 .

Improving the prediction of Pseudomonas putida mt-2 growth kinetics with the use of a gene expression regulation model of the TOL plasmid

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Víctor de Lorenzo, 2011 .

Biological therapy of bone defects: the immunology of bone allo-transplantation

Athanasios Mantalaris, Pavlos Panteliadis, Eleftherios Tsiridis, 2010, Expert opinion on biological therapy.

Toward Global Parametric Estimability of a Large-Scale Kinetic Single-Cell Model for Mammalian Cell Cultures

Steven P. Asprey, Athanasios Mantalaris, S. P. Asprey, 2005 .

Nanosensors for regenerative medicine.

Athanasios Mantalaris, Chenjie Xu, Christian Wiraja, 2014, Journal of biomedical nanotechnology.

Simulation of ex vivo bone marrow culture: Application to chronic myeloid leukaemia growth model

Athanasios Mantalaris, Nicki Panoskaltsis, Xiao Yun Xu, 2012 .

Nanocellulose enhanced interfaces in truly green unidirectional fibre reinforced composites

Athanasios Mantalaris, Alexander Bismarck, Julasak Juntaro, 2007 .

A Cyclin Distributed Cell Cycle Model in GS-NS0

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2014 .

Modelling the Delta1/Notch1 Pathway: In Search of the Mediator(s) of Neural Stem Cell Differentiation

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Alexandros Kiparissides, 2011, PloS one.

Biocompatible ion selective electrode for monitoring metabolic activity during the growth and cultivation of human cells.

Christofer Toumazou, Mayasari Lim, Athanasios Mantalaris, 2008, Biosensors & bioelectronics.

The regulatory logic of m-xylene biodegradation by Pseudomonas putida mt-2 exposed by dynamic modelling of the principal node Ps/Pr of the TOL plasmid.

Athanasios Mantalaris, Victor de Lorenzo, Alexandros Kiparissides, 2009, Environmental microbiology.

Development and Analysis of a Mathematical Model for Antibody‐Producing GS‐NS0 Cells Under Normal and Hyperosmotic Culture Conditions

Athanasios Mantalaris, Julie Varley, A. Mantalaris, 2006, Biotechnology progress.

Developing a cyclin blueprint as a tool for mapping the cell cycle in GS-NS0

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2013 .

Molecular and thermodynamic basis for EGCG‐Keratin interaction‐part I: Molecular dynamics simulations

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Lujia Han, 2013 .

Parametric identifiability of a structured kinetic model for mammalian cell cultures

Steven P. Asprey, Athanasios Mantalaris, Fabio R. Sidoli, 2003 .

Molecular and thermodynamic basis for EGCG‐Keratin interaction‐part II: Experimental investigation

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Lujia Han, 2013 .

Development of an ex vivo bone marrow mimicry microenvironment in a novel 3D hollow fibre bioreactor

Athanasios Mantalaris, Ruth Misener, Nicki Panoskaltsis, 2015 .

Analysis of an Individualized Physiologically Based Model for Anesthesia Control

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2012 .

Biology Of Mixed Phenotype Acute Leukemia In Successful Long-Term Cytokine-Free Three-Dimensional (3D) Static and Perfused 3D Hollow-Fibre Bioreactor Culture

Athanasios Mantalaris, Maria Rende, Nicki Panoskaltsis, 2013 .

Stem Cells as Building Blocks

Athanasios Mantalaris, Peter I. Lelkes, Julia M. Polak, 2014 .

A Predictive Model for Energy Metabolism and ATP Balance in Mammalian Cells: Towards the Energy-Based Optimization of mAb Production

Efstratios N. Pistikopoulos, Athanasios Mantalaris, Maria M. Papathanasiou, 2016 .

Enhanced derivation of osteogenic cells from murine embryonic stem cells after treatment with HepG2-conditioned medium and modulation of the embryoid body formation period: application to skeletal tissue engineering.

Athanasios Mantalaris, Yu-Shik Hwang, Julia M. Polak, 2006, Tissue engineering.

An automated system for the design of optimal personalized chemotherapy protocols for the treatment of Leukemia

Efstratios N. Pistikopoulos, Michael C. Georgiadis, Athanasios Mantalaris, 2013 .

The use of murine embryonic stem cells, alginate encapsulation, and rotary microgravity bioreactor in bone tissue engineering.

Athanasios Mantalaris, Sergei G. Kazarian, Aldo R. Boccaccini, 2009, Biomaterials.

Integrated 3-dimensional expansion and osteogenic differentiation of murine embryonic stem cells.

Athanasios Mantalaris, Sergei G. Kazarian, Yu-Shik Hwang, 2007, Tissue engineering.

Engineering a mimicry of bone marrow tissue ex vivo.

Athanasios Mantalaris, Nicki Panoskaltsis, A. Mantalaris, 2005, Journal of bioscience and bioengineering.

Development of a Hematopoietic Microenvironment for the Production of Red Blood Cells (RBCs) in a Novel 3D Hollow Fibre Bioreactor

Athanasios Mantalaris, Ruth Misener, Nicki Panoskaltsis, 2015 .