Carlos López-Otín

发表

Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.

C. López-Otín, M. Balbín, J. Tolivia, 1994, The Journal of biological chemistry.

Pepsinogen C is a new prognostic marker in primary breast cancer.

C. López-Otín, F. Vizoso, L. M. Sánchez, 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.

C. López-Otín, J. Freije, P. Crespo, 1999, Genomics.

Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor.

C. López-Otín, M. Takigawa, M. Balbín, 1998, The American journal of pathology.

Cathepsin D in breast secretions from women with breast cancer.

A. Ferrando, C. López-Otín, Á. Ruibal, 1993, British Journal of Cancer.

The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21

C. López-Otín, A. Gutiérrez-Fernández, R. Gomis, 2014, Oncogene.

Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis.

C. López-Otín, M. Ståhle-Bäckdahl, B. Sandstedt, 1997, Laboratory investigation; a journal of technical methods and pathology.

Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family.

A. Ferrando, C. López-Otín, J. Freije, 1994, Cancer research.

Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor.

I. Olafsson, C. López-Otín, J. Freije, 1991, The Journal of biological chemistry.

Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis

C. López-Otín, A. Bohm, A. Agarwal, 2014, Oncogene.

Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3.

C. López-Otín, M. d’Ortho, R. Hembry, 1998, The Biochemical journal.

High levels of expression of collagenase-3 (MMP-13) in pathological conditions associated with a foreign-body reaction.

S. Santavirta, C. López-Otín, Y. Konttinen, 1998, The Journal of bone and joint surgery. British volume.

Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.

B. Nielsen, C. López-Otín, L. Lund, 2001, Cancer research.

Microcephalia with mandibular and dental dysplasia in adult Zmpste24‐deficient mice

J. Freije, A. Germanà, F. Carlos, 2008, Journal of anatomy.

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome

E. Giné, A. López-Guillermo, E. Campo, 2013, Leukemia.

Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases

C. López-Otín, J. Ghiso, E. Levy, 1989, The Journal of experimental medicine.

Rye inhibitors of animal alpha-amylases show different specificities, aggregative properties and IgE-binding capacities than their homologues from wheat and barley.

C. López-Otín, G. García-Casado, G. Salcedo, 1994, European journal of biochemistry.

Activation of progelatinase B (proMMP-9) by active collagenase-3 (MMP-13).

C. López-Otín, B. Smith, G. Murphy, 1997, European journal of biochemistry.

A protein related to brain microtubule-associated protein MAP1B is a component of the mammalian centrosome.

C. López-Otín, B. Buendia, J. Ávila, 1994, Journal of cell science.

Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease.

C. López-Otín, J. Freije, M. Balbín, 1990, The Biochemical journal.

Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions.

C. López-Otín, M. Seiki, M. Ståhle-Bäckdahl, 1997, Cancer research.