C. Downes

Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

C. Downes, G. Kular, J. Lucocq, 2002, The Biochemical journal.

MyosinV controls PTEN function and neuronal cell size

R. Hindges, B. Eickholt, C. Downes, 2009, Nature Cell Biology.

PTEN is destabilized by phosphorylation on Thr366.

Helene Maccario, Lindsay Davidson, C. Downes, 2007, The Biochemical journal.

PTEN function: how normal cells control it and tumour cells lose it.

C. Downes, N. Leslie, C. Downes, 2004, The Biochemical journal.

The lipid phosphatase activity of PTEN is critical for its tumor supressor function.

M. Wigler, M. Myers, N. Tonks, 1998, Proceedings of the National Academy of Sciences of the United States of America.

TPIP: a novel phosphoinositide 3-phosphatase.

C. Downes, N. Leslie, S. Walker, 2001, The Biochemical journal.

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

D. Alessi, C. Downes, L. Trinkle-Mulcahy, 2002 .

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

I. Batty, C. Downes, N. Leslie, 2004, The Biochemical journal.

PTEN M-CBR3, a Versatile and Selective Regulator of Inositol 1,3,4,5,6-Pentakisphosphate (Ins(1,3,4,5,6)P5)

C. Downes, N. Leslie, R. Clarke, 2004, Journal of Biological Chemistry.