Hong Wang

发表

Monocytes and Macrophages in Atherosclerosis

Xiaofeng Yang, Pu Fang, Hong Wang, 2015 .

HDL subclass proteomic analysis and functional implication of protein dynamic change during HDL maturation

A. Remaley, Xiaofeng Yang, J. Saredy, 2019, Redox biology.

Immune cell subset differentiation and tissue inflammation

Xiaofeng Yang, Jingfeng Wang, Xinyuan Li, 2018, Journal of Hematology & Oncology.

THE FORKHEAD TRANSCRIPTION FACTORS ARE IMPORTANT IN REGULATING VASCULAR PATHOLOGY , DIABETES AND REGULATORY T CELLS

Ying-Xuan Yin, Xiaofeng Yang, Pu Fang, 2010 .

Immune Responses to Stem Cells and Cancer Stem Cells

Xiaofeng Yang, Hong Wang, Hong Wang, 2009 .

Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity

Xiaofeng Yang, Hong Wang, C. Drummer, 2018, Front. Physiol..

A Novel Subset of CD95+ Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Xiaofeng Yang, Pu Fang, Yu Sun, 2021, Frontiers in Immunology.

Caspase-1 recognizes extended cleavage sites in its natural substrates.

Jerry Shen, Ying-Xuan Yin, Xiaofeng Yang, 2010, Atherosclerosis.

Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells.

Xiaoshu Cheng, Xiaofeng Yang, Jingfeng Wang, 2016, Circulation research.

Versatile cell ablation tools and their applications to study loss of cell functions

Hongzhen Hu, S. Ergün, B. Aktas, 2019, Cellular and Molecular Life Sciences.

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

David L. Williams, Xiaofeng Yang, N. Snyder, 2022, JCI insight.

Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers.

Xiaofeng Yang, Yu Sun, Yifan Lu, 2020, Pharmacology & therapeutics.

ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Xianwei Wang, Xiaofeng Yang, J. Saredy, 2020, Redox biology.

Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice

P. Blackshear, Xiaofeng Yang, S. Lessner, 2020, Redox biology.

Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells

Xiaofeng Yang, Xinyuan Li, Pu Fang, 2019, Redox biology.

Proton leak regulates mitochondrial reactive oxygen species generation in endothelial cell activation and inflammation - A novel concept.

Xiaofeng Yang, Hong Wang, Gayani K. Nanayakkara, 2019, Archives of biochemistry and biophysics.

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses—Inflammations and Cancers Can Have High Genomic Risks

Joon-Young Park, Xiaofeng Yang, Lijian Shao, 2018, Front. Physiol..

A Double-edged Sword: Uric Acid and Neurological Disorders

Xiaofeng Yang, Xinyuan Li, Pu Fang, 2013, Brain disorders & therapy.

Innate-adaptive immunity interplay and redox regulation in immune response

Xianwei Wang, Xiaofeng Yang, J. Saredy, 2020, Redox biology.

Hyperhomocystinemia Impairs Endothelial Function and eNOS Activity via PKC Activation

W. Durante, Xiaofeng Yang, R. Bryan, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Increasing Upstream Chromatin Long–Range Interactions May Favor Induction of Circular RNAs in LysoPC-Activated Human Aortic Endothelial Cells

Yan Zhou, Daohai Yu, Xiaofeng Yang, 2019, Front. Physiol..

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Xiaofeng Yang, Yu Sun, Yifan Lu, 2021, Redox biology.

Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation

Xin Wang, P. Moore, Ying Yu, 2016, Diabetes.

SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)–Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation

Hongshan Chen, Xin Wang, Chan Chen, 2020, Circulation.

Vascular Endothelial Cells and Innate Immunity.

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?

Jia-min Zhuo, D. Praticò, Hong Wang, 2011, Trends in pharmacological sciences.

Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia.

R. Banerjee, Hong Wang, You Zhou, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint.

Xiaofeng Yang, Hong Wang, T. Tang, 2020, Pharmacology & therapeutics.

Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene Induction, Immunosuppressor Cell Promotion, and Enhancement of Exosome Biogenesis and Docking

Xiaofeng Yang, William Y. Yang, Yu Sun, 2017, Front. Physiol..

Biochemical basis and metabolic interplay of redox regulation

Xianwei Wang, Xiaofeng Yang, Hong Wang, 2019, Redox biology.

Model of stimulation-responsive splicing and strategies in identification of immunogenic isoforms of tumor antigens and autoantigens.

Xiaofeng Yang, Hong Wang, Fan Yang, 2006, Clinical immunology.

Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes.

Leif E. Peterson, Xiaofeng Yang, Hong Wang, 2004, The Journal of allergy and clinical immunology.

STIMulating a new treatment for sepsis.

S. Houser, W. Koch, M. Madesh, 2013, Lab animal.

Uncoupling protein 2‐mediated metabolic adaptations define cardiac cell function in the heart during transition from young to old age

S. Houser, F. Recchia, S. Mohsin, 2020, Stem cells translational medicine.

Metabolic Reprogramming in Immune Response and Tissue Inflammation

Xiaofeng Yang, Zuyi Yuan, Hong Wang, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Hyperhomocysteinemia and Hyperglycemia Induce and Potentiate Endothelial Dysfunction via m-Calpain

M. Madesh, Xiaofeng Yang, S. Eguchi, 2014 .

The Microbial Metabolite Trimethylamine N-Oxide Links Vascular Dysfunctions and the Autoimmune Disease Rheumatoid Arthritis

Xiaofeng Yang, Yu Sun, Fatma Saaoud, 2019, Nutrients.

Severe Hyperhomocysteinemia Promotes Bone Marrow–Derived and Resident Inflammatory Monocyte Differentiation and Atherosclerosis in LDLr/CBS-Deficient Mice

S. Houser, Xiaofeng Yang, Jodene K Moore, 2012, Circulation research.

Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice

K. Lau, A. Di Carlo, N. Jhala, 2020, Pathogens.

Lymphocytes and Atherosclerosis

Xiaofeng Yang, Hong Wang, J. Mai, 2015 .

Expression of TCTP antisense in CD25(high) regulatory T cells aggravates cuff-injured vascular inflammation.

Ying-Xuan Yin, Xiaofeng Yang, Pu Fang, 2009, Atherosclerosis.

Regulatory T cells and Atherosclerosis.

Xiaofeng Yang, Hong Wang, Ramón Cueto, 2012, Journal of clinical & experimental cardiology.

Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

D. Praticò, Xiaofeng Yang, Jianxin Sun, 2021, Frontiers in Cardiovascular Medicine.

Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody

Hong Wang, Fan Yang, Xiao-mou Wei, 2015, Virology Journal.

Lysophospholipids and their G protein-coupled receptors in atherosclerosis.

Xiaofeng Yang, Xinyuan Li, Hong Wang, 2016, Frontiers in bioscience.

Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Daohai Yu, Xiaofeng Yang, J. Saredy, 2019, Front. Immunol..

A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis

Xiaofeng Yang, Lee F. Peng, Bin Gao, 2023, Theranostics.

Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells.

Xiaoshu Cheng, Xiaofeng Yang, Jingfeng Wang, 2016, Circulation research.

Hyperhomocysteinemia suppresses bone marrow CD34+/VEGF receptor 2+ cells and inhibits progenitor cell mobilization and homing to injured vasculature—a role of β1‐integrin in progenitor cell migration and adhesion

S. Houser, Xiaofeng Yang, Jingfeng Wang, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Methylation and Atherosclerosis

Xiaofeng Yang, Hong Wang, Shu Meng, 2015 .

Mechanisms in homocysteine-induced vascular disease

Hong Wang, Hongmei Tan, Fan Yang, 2005 .

Hyperhomocysteinemia and atherosclerosis.

Hong Wang, Fan Yang, Honglei Tan, 2005, Sheng li xue bao : [Acta physiologica Sinica].

Caspase-1 Plays a Critical Role in Accelerating Chronic Kidney Disease-Promoted Neointimal Hyperplasia in the Carotid Artery

Xiaofeng Yang, Xinyuan Li, Hong Wang, 2016, Journal of Cardiovascular Translational Research.

Hydrogen Sulfide Alleviates Liver Injury Through the S‐Sulfhydrated‐Kelch‐Like ECH‐Associated Protein 1/Nuclear Erythroid 2–Related Factor 2/Low‐Density Lipoprotein Receptor–Related Protein 1 Pathway

Hongshan Chen, Yuanqing Gao, Hong Wang, 2020, Hepatology.

LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury

W. Koch, S. Mohsin, Tao Wang, 2021, Redox biology.

Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

Xiaofeng Yang, J. Saredy, William Y. Yang, 2020, Frontiers in Immunology.

End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Daohai Yu, Yafeng Li, Rongshan Li, 2020, Redox biology.

Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions

Daohai Yu, Xiaofeng Yang, William Y. Yang, 2019, Front. Oncol..

Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Rongshan Li, Xiaofeng Yang, J. Saredy, 2021, Frontiers in Immunology.

Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD

N. Jhala, Xiaofeng Yang, Yu Sun, 2021, Journal of immunology research.

IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

E. Shevach, Xiaofeng Yang, William Y. Yang, 2021, JCI insight.

Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

Xiaofeng Yang, J. Saredy, Yu Sun, 2021, Frontiers in Immunology.

Immunological Feature and Transcriptional Signaling of Ly6C Monocyte Subsets From Transcriptome Analysis in Control and Hyperhomocysteinemic Mice

Pingping Yang, Xiaofeng Yang, J. Saredy, 2021, Frontiers in Immunology.

Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling

Xiaofeng Yang, Pu Fang, William Y. Yang, 2019, Redox biology.

Ly6C+ Inflammatory Monocyte Differentiation Partially Mediates Hyperhomocysteinemia-Induced Vascular Dysfunction in Type 2 Diabetic db/db Mice.

Xiaofeng Yang, J. Saredy, Xinyuan Li, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Caspase-1 mediates hyperlipidemia-weakened progenitor cell vessel repair.

S. Houser, M. Madesh, D. Tilley, 2016, Frontiers in bioscience.

Hyperhomocysteinemia Decreases Circulating High-Density Lipoprotein by Inhibiting Apolipoprotein A-I Protein Synthesis and Enhancing HDL Cholesterol Clearance

R. Hui, H. Pownall, W. Durante, 2006, Circulation research.

S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction.

Hongshan Chen, Hong Wang, Yong Ji, 2019, Arteriosclerosis, thrombosis, and vascular biology.

SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells.

P. Moore, M. Xian, Y. Shao, 2016, Antioxidants & redox signaling.

Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells – Novel qualification markers for chronic disease risk factors and conditional DAMPs

Daohai Yu, Xiaofeng Yang, Xinyuan Li, 2019, Redox biology.

Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis

Yan Zhou, Daohai Yu, K. Bayless, 2020, Frontiers in Immunology.

Complement Inhibition Targeted to Injury Specific Neoepitopes Attenuates Atherogenesis in Mice

Xiaofeng Yang, Hong Wang, S. Tomlinson, 2021, Frontiers in Cardiovascular Medicine.

Molecular processes mediating hyperhomocysteinemia-induced metabolic reprogramming, redox regulation and growth inhibition in endothelial cells

Xiaofeng Yang, Xiaohua Jiang, Hong Wang, 2021, Redox biology.

Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

P. Datta, Xiaofeng Yang, B. Aktas, 2020, Nature Communications.

Role of TRPC1 and NF-κB in mediating angiotensin II-induced Ca2+ entry and endothelial hyperpermeability

Hong Wang, R. Guo, Yan-kun Shi, 2009, Peptides.

Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy

Xin Wang, P. Moore, Ying Yu, 2016, Journal of the American Heart Association.

Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation

Xiaofeng Yang, Xinyuan Li, Pu Fang, 2018, The Journal of Biological Chemistry.

Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation

Xin Wang, P. Moore, Ying Yu, 2016, Diabetes.

An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity

Xiaofeng Yang, Hong Wang, Yu Yang, 2005, Oncogene.

Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors.

S. Zhang, Xiaofeng Yang, Hong Wang, 2005, The Biochemical journal.

S-nitrosylation-mediated coupling of G-protein alpha-2 with CXCR5 induces Hippo/YAP-dependent diabetes-accelerated atherosclerosis

Hongshan Chen, Shixiu Sun, Shanshan Luo, 2021, Nature Communications.

Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling

L. Watson, Liqing Zhang, Yonggang Zhang, 2018, BMC Medical Genomics.

Editorial: Insights in cardiovascular therapeutics 2022—cardiovascular innate immunity

Xiaofeng Yang, Hong Wang, Yifan Lu, 2023, Frontiers in Cardiovascular Medicine.

Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy.

W. Koch, Joon-Young Park, M. Madesh, 2019, Journal of molecular and cellular cardiology.

Lysophospholipids and their G protein-coupled receptors in atherosclerosis.

Xiaofeng Yang, Xinyuan Li, Hong Wang, 2016, Frontiers in bioscience.

Atherosclerosis: Risks, Mechanisms, and Therapies

D. Praticò, C. Patterson, N. Sibinga, 2015 .

An Unconventional Antigen Translated by a Novel Internal Ribosome Entry Site Elicits Antitumor Humoral Immune Reactions1

S. Verstovsek, R. Silver, J. Prchal, 2006, The Journal of Immunology.

Novel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia vera.

S. Verstovsek, R. Silver, J. Prchal, 2007, Clinical immunology.

Antitumor Humoral Immune Reactions Novel Internal Ribosome Entry Site Elicits An Unconventional Antigen Translated by a

S. Verstovsek, R. Silver, J. Prchal, 2006 .