E. van Obberghen

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Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity

T. Hansen, O. Pedersen, E. Van Obberghen, 1999, Diabetologia.

MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines*

N. Baroukh, M. Ravier, M. Loder, 2007, Journal of Biological Chemistry.

Potential Role of Protein Kinase B in Glucose Transporter 4 Translocation in Adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Endocrinology.

Wortmannin inhibits the action of insulin but not that of okadaic acid in skeletal muscle: comparison with fat cells.

E. Van Obberghen, Y. Le Marchand-Brustel, M. Cormont, 1995, Endocrinology.

Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Endocrinology.

Differential Role of Insulin Receptor Substrate (IRS)-1 and IRS-2 in L6 Skeletal Muscle Cells Expressing the Arg1152 → Gln Insulin Receptor*

E. Van Obberghen, G. Condorelli, F. Oriente, 1999, The Journal of Biological Chemistry.

cAMP stimulates protein kinase B in a Wortmannin‐insensitive manner

E. Van Obberghen, B. Hemmings, N. Filippa, 1997, FEBS letters.

Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes*

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1996, The Journal of Biological Chemistry.

The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro.

E. Van Obberghen, R. Ballotti, A. Kowalski-Chauvel, 1993, The Journal of biological chemistry.

Insulin and okadaic acid induce Rab4 redistribution in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The Journal of biological chemistry.

SOCS-3 Is an Insulin-induced Negative Regulator of Insulin Signaling*

E. Van Obberghen, B. Emanuelli, D. Hilton, 2000, The Journal of Biological Chemistry.

Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase

E. Van Obberghen, B. Hemmings, N. Filippa, 1999, Molecular and Cellular Biology.

Involvement of protein kinase B and mitogen‐activated protein kinases in experimental normothermic liver ischaemia–reperfusion injury

E. Van Obberghen, J. Gugenheim, R. Cursio, 2006, The British journal of surgery.

Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinase.

E. Van Obberghen, E. Chambaz, S. Rocchi, 2000, The Biochemical journal.

5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

E. Van Obberghen, D. Baetz, L. Counillon, 2008, Endocrinology.

Malnutrition is an independent factor associated with nosocomial infections.

E. Van Obberghen, X. Pivot, S. Schneider, 2004, The British journal of nutrition.

Inhibition of insulin receptor binding by dimethyl sulfoxide.

E. Van Obberghen, J. Roth, P. De Meyts, 1979, Biochimica et biophysica acta.

Glucose, Other Secretagogues, and Nerve Growth Factor Stimulate Mitogen-activated Protein Kinase in the Insulin-secreting β-Cell Line, INS-1 (*)

E. Van Obberghen, M. Prentki, C. Wollheim, 1995, The Journal of Biological Chemistry.

Potential role of Rab4 in the regulation of subcellular localization of Glut4 in adipocytes

E. Van Obberghen, Y. Le Marchand-Brustel, Y. Marchand-Brustel, 1996, Molecular and cellular biology.

Parallel changes in Glut 4 and Rab4 movements in two insulin‐resistant states

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1994, FEBS letters.

Matrix Metalloproteinases Are Differentially Expressed in Adipose Tissue during Obesity and Modulate Adipocyte Differentiation*

E. Van Obberghen, B. Mari, S. Tartare-Deckert, 2003, The Journal of Biological Chemistry.

Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from gold thioglucose obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, N. Gautier, 1995, The American journal of physiology.

Glucocorticoid-induced insulin resistance in vitro: evidence for both receptor and postreceptor defects.

C. Kahn, E. Van Obberghen, C. Grunfeld, 1981, Endocrinology.

The carboxyl-terminal domain of the insulin receptor: its potential role in growth-promoting effects.

E. Van Obberghen, V. Baron, P. Kaliman, 1991, Biochemistry.

Molecular mechanisms of insulin receptor substrate protein‐mediated modulation of insulin signalling

E. Van Obberghen, L. Pirola, A. M. Johnston, 2003, FEBS letters.

Effect of Phosphoinositide-Dependent Kinase 1 on Protein Kinase B Translocation and Its Subsequent Activation

E. Van Obberghen, B. Hemmings, N. Filippa, 2000, Molecular and Cellular Biology.

Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1996, European journal of biochemistry.

Phosphorylation of Insulin Receptor Substrate-1 on Multiple Serine Residues, 612, 632, 662, and 731, Modulates Insulin Action (*)

E. Van Obberghen, Isabelle Mothe, E. van Obberghen, 1996, The Journal of Biological Chemistry.

Antibodies to phosphotyrosine injected in Xenopus laevis oocytes modulate maturation induced by insulin/IGF-I.

E. Van Obberghen, P. Hainaut, R. Ballotti, 1991, Experimental cell research.

Insulin-like effects of vanadate on glucose uptake and on maturation in Xenopus laevis oocytes.

E. Van Obberghen, P. Hainaut, S. Giorgetti, 1991, Cell regulation.

Effect of a thermogenic agent, BRL 26830A, on insulin receptors in obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1988, The American journal of physiology.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

E. Van Obberghen, M. Sajan, R. Farese, 2010, American journal of physiology. Endocrinology and metabolism.

Insulin Induces Suppressor of Cytokine Signaling-3 Tyrosine Phosphorylation through Janus-activated Kinase*

E. Van Obberghen, B. Emanuelli, D. Hilton, 2001, The Journal of Biological Chemistry.

Fast urinary screening of oligosaccharidoses by MALDI-TOF/TOF mass spectrometry

E. Van Obberghen, C. Caruba, M. Piraud, 2014, Orphanet Journal of Rare Diseases.

miR-139 impacts FoxO1 action by decreasing FoxO1 protein in mouse hepatocytes.

E. Van Obberghen, P. Lebrun, N. Gautier, 2009, Biochemical and biophysical research communications.

Function of microRNA‐375 and microRNA‐124a in pancreas and brain

N. Baroukh, E. Van Obberghen, E. van Obberghen, 2009, The FEBS journal.

miR-375 Targets 3′-Phosphoinositide–Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic β-Cells

N. Baroukh, E. Van Obberghen, D. Pipeleers, 2008, Diabetes.

Assessment of Folate Status: Measurement of Homocysteine versus Vitamin B12 and Folate

E. Van Obberghen, M. Candito, B. Houcher, 2004 .

Argonaute-2 is associated to brown adipose tissue activation.

E. Van Obberghen, N. Gautier, O. Dumortier, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway*

G. Semenza, E. Van Obberghen, C. Treins, 2002, The Journal of Biological Chemistry.

Regulation of Vascular Endothelial Growth Factor Expression by Advanced Glycation End Products*

E. Van Obberghen, C. Treins, J. Murdaca, 2001, The Journal of Biological Chemistry.

Insulin and Insulin-like Growth Factor-I Induce Vascular Endothelial Growth Factor mRNA Expression via Different Signaling Pathways*

E. Van Obberghen, N. Filippa, C. Miele, 2000, The Journal of Biological Chemistry.

Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion.

E. Van Obberghen, J. Gugenheim, R. Cursio, 2006, Transplantation proceedings.

Shaping and preserving β‐cell identity with microRNAs

E. Van Obberghen, O. Dumortier, G. Fabris, 2016, Diabetes, obesity & metabolism.

Maternal Protein Restriction Leads to Pancreatic Failure in Offspring: Role of Misexpressed MicroRNA-375

E. Van Obberghen, N. Gautier, S. Patouraux, 2014, Diabetes.

MicroRNAs and metabolism crosstalk in energy homeostasis.

E. Van Obberghen, O. Dumortier, C. Hinault, 2013, Cell metabolism.

Methylglyoxal Impairs the Insulin Signaling Pathways Independently of the Formation of Intracellular Reactive Oxygen Species

E. Van Obberghen, Audrey Riboulet-Chavey, J. Murdaca, 2006, Diabetes.

Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice

E. Van Obberghen, J. Lawrence, N. Gautier, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Signalling through the insulin receptor and the insulin-like growth factor-I receptor.

E. Van Obberghen, E. van Obberghen, 1994, Diabetologia.

Modulation of glucose metabolism by the renin-angiotensin-aldosterone system.

E. Van Obberghen, V. Esnault, G. Favre, 2015, American journal of physiology. Endocrinology and metabolism.

The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells.

E. Van Obberghen, B. Emanuelli, C. Filloux, 2004, Diabetes.

SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice*

E. Van Obberghen, B. Emanuelli, D. Hilton, 2001, The Journal of Biological Chemistry.

Differential effects of okadaic acid on insulin-stimulated glucose and amino acid uptake and phosphatidylinositol 3-kinase activity.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The Journal of biological chemistry.

IRS‐1 and IRS‐2 are recruited by TrkA receptor and oncogenic TRK‐T1

E. Van Obberghen, M. Pierotti, C. Miele, 2001, Journal of cellular physiology.

Insulin Receptor Substrate-2 Binds to the Insulin Receptor through Its Phosphotyrosine-binding Domain and through a Newly Identified Domain Comprising Amino Acids 591786 (*)

E. Van Obberghen, M. White, S. Tartare-Deckert, 1996, The Journal of Biological Chemistry.

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786.

E. Van Obberghen, M. White, S. Tartare-Deckert, 1996, The Journal of biological chemistry.

Stat 5B, Activated by Insulin in a Jak-Independent Fashion, Plays a Role in Glucokinase Gene Transcription.

E. Van Obberghen, J. Girard, S. Tartare-Deckert, 2000, Endocrinology.

Stat 5B, activated by insulin in a Jak-independent fashion, plays a role in glucokinase gene transcription.

E. Van Obberghen, J. Girard, S. Tartare-Deckert, 2000, Endocrinology.

Fas ligand expression following normothermic liver ischemia-reperfusion.

E. Van Obberghen, P. Auberger, J. Gugenheim, 2005, The Journal of surgical research.

p125Fak Focal Adhesion Kinase Is a Substrate for the Insulin and Insulin-like Growth Factor-I Tyrosine Kinase Receptors*

E. Van Obberghen, V. Calléja, V. Baron, 1998, The Journal of Biological Chemistry.

Biological activities of EGF‐receptor mutants with individually altered autophosphorylation sites.

A. Ullrich, E. Van Obberghen, J. Schlessinger, 1988, The EMBO journal.

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

N. Ayache, M. Barlaud, E. Gilson, 2019, Cancers.

Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes

E. Van Obberghen, P. Nuutila, J. Chambard, 2016, Adipocyte.

Interaction of SH2-containing protein tyrosine phosphatase 2 with the insulin receptor and the insulin-like growth factor-I receptor: studies of the domains involved using the yeast two-hybrid system.

E. Van Obberghen, S. Rocchi, S. Tartare-Deckert, 1996, Endocrinology.

Characterization of 6-deoxy-6-iodo-D-glucose: a potential new tool to assess glucose transport.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Nuclear medicine and biology.

Interaction of Janus Kinases JAK-1 and JAK-2 with the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor.

V. Baron, P. Gual, E. van Obberghen, 1998, Endocrinology.

IRS-4 mediated mitogenic signalling by insulin and growth hormone in LB cells, a murine T-cell lymphoma devoid of IGF-I receptors.

B. Ursø, E. Van Obberghen, C. Christoffersen, 2003, Cellular signalling.

Insulin Receptor Substrate-1 as a Signaling Molecule for Focal Adhesion Kinase pp125FAK and pp60 src *

E. Van Obberghen, I. Mothe-Satney, P. Lebrun, 1998, The Journal of Biological Chemistry.

Okadaic acid stimulates IGF-II receptor translocation and inhibits insulin action in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The American journal of physiology.

Polymyxin B inhibits insulin-induced glucose transporter and IGF II receptor translocation in isolated adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1992, European journal of biochemistry.

Identification of the Rat Adapter Grb14 as an Inhibitor of Insulin Actions*

E. Van Obberghen, J. Girard, A. Burnol, 1998, The Journal of Biological Chemistry.

The interaction of 125I-insulin with cultured 3T3-L1 adipocytes: quantitative analysis by the hypothetical grain method.

L. Orci, E. Van Obberghen, C. Grunfeld, 1983, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Binding, internalization, and lysosomal association of 125I-human growth hormone in cultured human lymphocytes: a quantitative morphological and biochemical study

L. Orci, E. Van Obberghen, J. Carpentier, 1980, The Journal of cell biology.

Insulin receptors, receptor antibodies, and the mechanism of insulin action.

C. Kahn, E. Van Obberghen, M. Kasuga, 1981, Recent progress in hormone research.

SOCS proteins causing trouble in insulin action

P. Lebrun, E. van Obberghen, 2007, Acta physiologica.

Insulin Receptor Substrate-2 Phosphorylation Is Necessary for Protein Kinase Cζ Activation by Insulin in L6hIR Cells*

E. Van Obberghen, F. Oriente, P. Formisano, 2001, The Journal of Biological Chemistry.

FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes

E. Van Obberghen, S. Rocchi, J. Mas, 2008, Diabetes.

Evidence for a Differential Interaction of SHC and the Insulin Receptor Substrate-1 (IRS-1) with the Insulin-like Growth Factor-I (IGF-I) Receptor in the Yeast Two-hybrid System (*)

E. Van Obberghen, J. Murdaca, S. Tartare-Deckert, 1995, The Journal of Biological Chemistry.

Oligomeric states of the insulin receptor: binding and autophosphorylation properties.

E. Van Obberghen, J. Kubar, E. van Obberghen, 1989, Biochemistry.

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance

L. Groop, F. Schick, T. Tuomi, 2016, Diabetes.

Adipocytes Secrete Leukotrienes

E. Van Obberghen, C. Filloux, P. Grimaldi, 2012, Diabetes.

Insulin receptors in the mammalian central nervous system: binding characteristics and subunit structure.

S. Gammeltoft, E. Van Obberghen, M. Fehlmann, 1985, Biochimie.

Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.

E. Van Obberghen, D. Accili, Á. Valverde, 2007, Endocrinology.

Effects of age, malnutrition and refeeding on the expression and secretion of ghrelin.

E. Van Obberghen, R. Al-Jaouni, S. Schneider, 2008, Clinical nutrition.

Fatty Aldehyde Dehydrogenase

E. Van Obberghen, L. Pirola, S. Rocchi, 2004, Journal of Biological Chemistry.

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85α

T. Hansen, O. Pedersen, C. Kahn, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of wild type and dominant-negative p55PIK regulatory subunit of phosphatidylinositol 3-kinase with insulin-like growth factor-1 signaling proteins.

E. Van Obberghen, M. White, C. Filloux, 1997, Molecular endocrinology.

Tyr624 and Tyr628 in Insulin Receptor Substrate-2 Mediate Its Association with the Insulin Receptor*

E. Van Obberghen, M. White, C. Filloux, 1997, The Journal of Biological Chemistry.

Contribution of the Long Noncoding RNA H19 to β-Cell Mass Expansion in Neonatal and Adult Rodents

M. Prentki, D. R. Laybutt, R. Regazzi, 2018, Diabetes.

Insulin stimulates phosphatidylinositol-3-kinase activity in rat adipocytes.

E. Van Obberghen, R. Ballotti, A. Kowalski-Chauvel, 1992, European journal of biochemistry.

Insulin binding to its receptor induces a conformational change in the receptor C-terminus.

E. Van Obberghen, P. Hainaut, S. Lavielle, 1990, Biochemistry.

Phosphorylation of the hepatic insulin receptor

E. Van Obberghen, A. Kowalski, E. van Obberghen, 1982, FEBS letters.

Activation Loop Sequences Confer Substrate Specificity to Phosphoinositide 3-Kinase α (PI3Kα)

M. Zvelebil, E. Van Obberghen, L. Pirola, 2001, The Journal of Biological Chemistry.

Insulin and tumor-promoting agent regulate an inhibitor of the 44-kDa mitogen-activated protein kinase/extracellular signal-regulated protein kinase 1 in fibroblasts.

E. Van Obberghen, P. Peraldi, E. van Obberghen, 1993, European journal of biochemistry.

The Matricellular Protein SPARC/Osteonectin as a Newly Identified Factor Up-regulated in Obesity*

E. Van Obberghen, S. Tartare-Deckert, N. Gautier, 2001, The Journal of Biological Chemistry.

Cross-talk between the Platelet-derived Growth Factor and the Insulin Signaling Pathways in 3T3-L1 Adipocytes*

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, The Journal of Biological Chemistry.

Fasting, postprandial, and post-methionine-load homocysteinaemia and methylenetetrahydrofolate reductase polymorphism in vascular disease

M. Candito, P. Gibelin, R. de Franchis, 1999, Journal of Inherited Metabolic Disease.

Nutritional and genetic determinants of vitamin B and homocysteine metabolisms in neural tube defects: A multicenter case–control study

E. Van Obberghen, D. Luton, J. Oury, 2008, American journal of medical genetics. Part A.

Involvement of the Pleckstrin Homology Domain in the Insulin-stimulated Activation of Protein Kinase B*

E. Van Obberghen, B. Hemmings, N. Filippa, 1998, The Journal of Biological Chemistry.

RNA Activation of the Vascular Endothelial Growth Factor Gene (VEGF) Promoter by Double-Stranded RNA and Hypoxia: Role of Noncoding VEGF Promoter Transcripts

E. Van Obberghen, K. Wagner, Pascal Lopez, 2016, Molecular and Cellular Biology.

How Does Our Knowledge on the Na+/H+ Exchanger NHE1 Obtained by Biochemical and Molecular Analyses Keep up With Its Recent Structure Determination?

E. Van Obberghen, Y. Bouret, L. Counillon, 2022, Frontiers in Physiology.

Evidence for a Direct Interaction between Insulin Receptor Substrate-1 and Shc*

E. Van Obberghen, J. Girard, S. Tartare-Deckert, 1997, The Journal of Biological Chemistry.

Dynamin Associates with Src-Homology Collagen (SHC) and Becomes Tyrosine Phosphorylated in Response to Insulin.

E. Van Obberghen, V. Baron, F. Alengrin, 1998, Endocrinology.

Grb10 Prevents Nedd4-mediated Vascular Endothelial Growth Factor Receptor-2 Degradation*

E. Van Obberghen, Sharad Kumar, C. Treins, 2004, Journal of Biological Chemistry.

The subunit structure of the insulin receptor and molecular interactions with major histocompatibility complex antigens.

E. Van Obberghen, Y. Chvatchko, N. Brossette, 1985, Biochimie.

Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport.

E. Van Obberghen, L. Pirola, S. Rusconi, 2003, Molecular endocrinology.

Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I.

E. Van Obberghen, C. Treins, J. Murdaca, 2005, Molecular endocrinology.

Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice

E. Van Obberghen, P. Lebrun, V. Esnault, 2014, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Incidence and Characteristics of Acute Kidney Injury in Severe Diabetic Ketoacidosis

E. Van Obberghen, C. Ichai, J. Orban, 2014, PloS one.

The Insulin Receptor and Insulin of the Atlantic Hagfish: Extraordinary Conservation of Binding Specificity and Negative Cooperativity in the Most Primitive Vertebrate

C. Kahn, E. Van Obberghen, S. Emdin, 1979, Diabetes.

Galanin can inhibit insulin release by a mechanism other than membrane hyperpolarization or inhibition of adenylate cyclase.

E. Van Obberghen, Y. Le Marchand-Brustel, M. Cormont, 1989, The Journal of biological chemistry.

Amino acid-induced regulation of hepatocyte growth: possible role of Drosha

E. Van Obberghen, N. Gautier, O. Dumortier, 2019, Cell Death & Disease.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

M. Sajan, R. Farese, F. Foufelle, 2010, American journal of physiology. Endocrinology and metabolism.

Insulin receptors: structure and function.

S. Gammeltoft, E. Van Obberghen, E. van Obberghen, 1986, Experientia.

The insulin receptor kinase.

S. Gammeltoft, E. Van Obberghen, R. Ballotti, 1985, Biochimie.

Interaction of the C-terminal acidic domain of the insulin receptor with histone modulates the receptor kinase activity.

E. Van Obberghen, V. Baron, F. Alengrin, 1995, European journal of biochemistry.

The insulin receptor C-terminus is involved in regulation of the receptor kinase activity.

E. Van Obberghen, J. Olefsky, N. Webster, 1993, Biochemistry.

Insulin receptors in rat brain: insulin stimulates phosphorylation of its receptor β‐subunit

S. Gammeltoft, E. Van Obberghen, M. Fehlmann, 1984, FEBS letters.

Dephosphorylation of the hepatic insulin receptor: absence of intrinsic phosphatase activity in purified receptors.

E. Van Obberghen, M. Fehlmann, H. Gazzano, 1983, Biochemical and biophysical research communications.

Insulin receptor: tyrosine kinase activity and insulin action.

S. Gammeltoft, E. Van Obberghen, R. Ballotti, 1989, Reproduction, nutrition, development.

Direct demonstration of glycosylation of insulin receptor subunits by biosynthetic and external labeling: evidence for heterogeneity.

C. Kahn, E. Van Obberghen, M. Kasuga, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes.

E. Van Obberghen, L. Harrison, A. Itin, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Insulin receptor internalization and recycling: mechanism and significance.

L. Orci, E. Van Obberghen, J. Carpentier, 1985, Biochimie.

Dynamics of Insulin Release and Microtubular-microfilamentous System: VII. Do Microfilaments Provide the Motive Force for the Translocation and Extrusion of Beta Granules?

L. Orci, E. Van Obberghen, W. Malaisse, 1974, Diabetes.

Calcium Antagonists and Islet Function: I. Inhibition of Insulin Release by Verapamil

E. Van Obberghen, W. Malaisse, G. Somers, 1975, Diabetes.

Effected of insulin and insulin-like growth factor-I on glucose transport and its transporters in soleus muscle of lean and obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, N. Gautier, 1995, Metabolism: clinical and experimental.

Subcellular distribution of low molecular weight guanosine triphosphate-binding proteins in adipocytes: colocalization with the glucose transporter Glut 4.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1991, Endocrinology.

Cell surface receptors for insulin and human growth hormone. Effect of microtubule and microfilament modifiers.

E. Van Obberghen, J. Roth, P. De Meyts, 1976, The Journal of biological chemistry.

Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.

E. Van Obberghen, D. Luton, M. Candito, 2007, Birth defects research. Part A, Clinical and molecular teratology.

Focal Adhesion Kinase pp125FAK Interacts With the Large Conductance Calcium‐Activated hSlo Potassium Channel in Human Osteoblasts: Potential Role in Mechanotransduction

J. Girault, E. Van Obberghen, S. Rocchi, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Hrs is a positive regulator of VEGF and insulin signaling.

E. Van Obberghen, J. Murdaca, S. Giorgetti-Peraldi, 2007, Experimental cell research.

In Skeletal Muscle Advanced Glycation End Products (AGEs) Inhibit Insulin Action and Induce the Formation of Multimolecular Complexes Including the Receptor for AGEs*

E. Van Obberghen, A. Lombardi, F. Oriente, 2008, Journal of Biological Chemistry.

Human Glycated Albumin Affects Glucose Metabolism in L6 Skeletal Muscle Cells by Impairing Insulin-induced Insulin Receptor Substrate (IRS) Signaling through a Protein Kinase Cα-mediated Mechanism*

E. Van Obberghen, F. Oriente, P. Formisano, 2003, Journal of Biological Chemistry.

Insulin and insulin-like-growth-factor-I (IGF-I) receptors in Xenopus laevis oocytes. Comparison with insulin receptors from liver and muscle.

E. Van Obberghen, P. Hainaut, V. Baron, 1991, The Biochemical journal.

Identification of Stat 5B as a substrate of the insulin receptor.

E. Van Obberghen, C. Filloux, S. Tartare-Deckert, 1997, European journal of biochemistry.

Insulin-stimulated glucose transport in muscle. Evidence for a protein-kinase-C-dependent component which is unaltered in insulin-resistant mice.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1989, The Biochemical journal.

Spontaneous hypoglycaemia in the presence of both anti-insulin antibody and anti-insulin receptor antibody.

E. Van Obberghen, N. Gautier, A. Fredenrich, 2006, Diabetes & metabolism.

Transphosphorylation as a possible mechanism for insulin and epidermal growth factor receptor activation.

A. Ullrich, E. Van Obberghen, J. Schlessinger, 1990, The Journal of biological chemistry.

Intermolecular transphosphorylation between insulin receptors and EGF‐insulin receptor chimerae.

A. Ullrich, E. Van Obberghen, J. Schlessinger, 1989, The EMBO journal.

Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.

M. Zvelebil, E. Van Obberghen, L. Pirola, 2001, The Journal of biological chemistry.