Alessandro Sette

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Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Theodore G. Drivas, Justine C. Williams, J. Weaver, 2023, Nature Immunology.

SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-19

A. Grifoni, Alessandro Sette, Alessandra Franco, 2023, Autoimmunity.

concept of altered T cell functions in patients with severe disease. Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection

C. Riou, R. Goliath, K. Wilkinson, 2022 .

Early antiviral CD4 and CD8 T cell responses are associated with upper respiratory tract clearance of SARS-CoV-2

S. Crotty, C. Moser, D. Weiskopf, 2023, bioRxiv.

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

V. Nizet, A. Sette, S. Crotty, 2019, Science Translational Medicine.

Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth

B. Pulendran, J. Wrammert, H. Maecker, 2023, Cell.

Peptide vaccines against hepatitis B virus: from animal model to human studies.

A. Sette, W. Pichler, I. P. Hunziker, 2001, Molecular immunology.

T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and Numerous SARS-CoV-2-Specific CD4- CD8- Double Negative T Cells and Regulatory T Cells

Alessandro Sette, Alessandra Franco, Jaeyoon Song, 2024, International journal of molecular sciences.

Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA.2.86 variant.

H. Ljunggren, A. Grifoni, M. Buggert, 2024, Cell host & microbe.

Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4+ T cells

A. Sette, F. Ay, D. Weiskopf, 2020, bioRxiv.

Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

A. Greenplate, S. Hensley, D. Weiskopf, 2021, Nature Medicine.

PINK1 is a target of T cell responses in Parkinson’s disease

J. Sidney, C. L. Lindestam Arlehamn, A. Frazier, 2024, bioRxiv.

Pre-existing SARS-2-specific T cells are predicted to cross-recognize BA.2.86.

J. Sidney, A. Grifoni, Alessandro Sette, 2023, Cell host & microbe.

T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer’s disease

Alessandro Sette, Samuel N Lockhart, Suzanne Craft, 2023, Scientific reports.

High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response

S. Madhi, D. Gurdasani, T. Carstensen, 2024, Nature medicine.

Southeast Asia initiative to combat SARS-CoV-2 variants (SEACOVARIANTS) consortium

P. Cheah, A. Grifoni, R. Hamers, 2024, Wellcome open research.

Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions.

R. da Silva Antunes, Alessandro Sette, A-Reum Kim, 2024, Expert review of vaccines.

Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop

M. Kojima, R. da Silva Antunes, Pramod Shinde, 2024, bioRxiv.

Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations

T. Tan, Alessandro Sette, Ulrich Heininger, 2024, Human vaccines & immunotherapeutics.

Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans

L. Premkumar, D. Weiskopf, A. Grifoni, 2023, bioRxiv.

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

J. Brenchley, Xueqiao Liu, D. Weiskopf, 2024, PLoS pathogens.

Improved Selection of Peptide Sets With Optimal HLA and Pathogen Diversity Coverage

A. Grifoni, A. Tarke, Alessandro Sette, 2022 .

Targets of influenza Human T cell response are mostly conserved in H5N1

J. Sidney, F. Krammer, A. Grifoni, 2024, bioRxiv.

Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

R. Scheuermann, S. Mallal, A. Sette, 2023, bioRxiv.

Viral mutations, TCR antagonism and escape from the immune response.

A. Sette, F. Chisari, C. Ferrari, 1995, Current opinion in immunology.

Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants

A. Sigal, S. Richardson, J. Bhiman, 2024, PLOS global public health.