Ronald N. Germain

发表

Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells.

J. Yewdell, J. Bennink, R. Germain, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments.

R. Germain, F. Castellino, Ronald N. Germain, 1995, Immunity.

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody.

J. Yewdell, J. Bennink, R. Germain, 1997, Immunity.

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein

S. Putney, Ronald N. Germain, J. A. Berzofsky, 1989, The Journal of experimental medicine.

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments

J. Yewdell, R. Germain, O. Bakke, 1993, The Journal of experimental medicine.

Production, specificity, and functionality of monoclonal antibodies to specific peptide-major histocompatibility complex class II complexes formed by processing of exogenous protein.

R. Germain, C. Reis e Sousa, G. Zhong, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP)

F. Castellino, Guangming Zhong, Ronald N. Germain, 1996, The Journal of experimental medicine.

Peptides corresponding to CD4-interacting regions of murine MHC class II molecules modulate immune responses of CD4+ T lymphocytes in vitro and in vivo.

R. Germain, X. Shen, P. McPhie, 1996, Journal of immunology.

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

R. Germain, X. Shen, R. König, 1995, The Journal of experimental medicine.

Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment.

R. Germain, C. Layet, Ronald N. Germain, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexes

R. Germain, P Romagnoli, P. Romagnoli, 1995, The Journal of experimental medicine.

Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules.

J. Coligan, R. Germain, F. Zappacosta, 1998, Journal of immunology.