Meiyu Geng

发表

Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities

Jian Ding, M. Geng, Yin-chun Ji, 2016, Oncotarget.

Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against glioblastoma

Lin-jiang Tong, Hua Xie, Yan-yan Shen, 2023, Acta pharmaceutica Sinica. B.

Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis.

Min Huang, Shuai Tang, T. Yuan, 2023, Pharmacological research.

Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder

Huafang Li, Zuoquan Xie, Jingjing Huang, 2024, Psychiatry Research.

Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors.

Dingding Gao, Shuai Tang, Xinglu Cao, 2024, Bioorganic chemistry.

Low‐Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells

Shuai Tang, Congying Pu, Jun Xu, 2024, Advanced science.

Structure-based drug discovery of novel fused-pyrazolone carboxamide derivatives as potent and selective AXL inhibitors

Yu Zhou, Chunpu Li, Yin-chun Ji, 2023, Acta pharmaceutica Sinica. B.

Design, synthesis, and evaluation of thiazolecarboxamide derivatives as stimulator of interferon gene inhibitors.

Zuoquan Xie, Hefeng Zhang, Meiyu Geng, 2024, Molecular diversity.

A novel STING agonist with systemic and durable anti‐tumour activity

Zuoquan Xie, Ao Zhang, Xiyuan Wang, 2023, Clinical and Translational Discovery.

Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation.

Jing Ai, Hefeng Zhang, Meiyu Geng, 2024, Journal of biomolecular structure & dynamics.

Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.

Zhuqing Zhang, M. Geng, B. Xiong, 2021, Journal of medicinal chemistry.

13,14-seco withaphysalins from Physalis minima and their inhibitory effects on NLRP3 inflammasome activation.

Sheng Yao, Chunping Tang, Yang Ye, 2024, Bioorganic chemistry.