Tim Bergbrede

Small-molecule inhibitors of human mitochondrial DNA transcription

P. Cramer, J. Boros, C. Gustafsson, 2020, Nature.

An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms

Frank Fischer, Johannes Zerweck, Mike Schutkowski, 2013, Nature Communications.

An Adaptable High-Throughput Technology Enabling the Identification of Specific Transcription Modulators

C. Gustafsson, M. Falkenberg, T. Bergbrede, 2017, SLAS discovery : advancing life sciences R & D.

Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity

J. Zierath, A. Krook, R. Wibom, 2024, Nature metabolism.

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain

H. Sticht, T. Bergbrede, M. Marschall, 2015, Viruses.

Isotopic labeling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.

T. Bergbrede, K. Alexandrov, P. Bayer, 2006, Protein expression and purification.

Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

E. Larsson, C. Gustafsson, P. Nussbaumer, 2024, bioRxiv.

Inhibition of mammalian mtDNA transcription paradoxically activates liver fatty acid oxidation to reverse diet-induced hepatosteatosis and obesity

J. Zierath, A. Krook, Shan Jiang, 2023, bioRxiv.

OCT4 interprets and enhances nucleosome flexibility

H. Schöler, T. Bergbrede, Vlad Cojocaru, 2022, bioRxiv.